Search Results - "Gómez‐Martín, Diana"

Metabolomics analysis reveals a modified amino acid metabolism that correlates with altered oxygen homeostasis in COVID-19 patients by Páez-Franco, José C., Torres-Ruiz, Jiram, Sosa-Hernández, Víctor A., Cervantes-Díaz, Rodrigo, Romero-Ramírez, Sandra, Pérez-Fragoso, Alfredo, Meza-Sánchez, David E., Germán-Acacio, Juan Manuel, Maravillas-Montero, José L., Mejía-Domínguez, Nancy R., Ponce-de-León, Alfredo, Ulloa-Aguirre, Alfredo, Gómez-Martín, Diana, Llorente, Luis

“…We identified the main changes in serum metabolites associated with severe (n = 46) and mild (n = 19) COVID-19 patients by gas chromatography coupled to mass…”
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B Cell Subsets as Severity-Associated Signatures in COVID-19 Patients by Sosa-Hernández, Víctor A, Torres-Ruíz, Jiram, Cervantes-Díaz, Rodrigo, Romero-Ramírez, Sandra, Páez-Franco, José C, Meza-Sánchez, David E, Juárez-Vega, Guillermo, Pérez-Fragoso, Alfredo, Ortiz-Navarrete, Vianney, Ponce-de-León, Alfredo, Llorente, Luis, Berrón-Ruiz, Laura, Mejía-Domínguez, Nancy R, Gómez-Martín, Diana, Maravillas-Montero, José L

“…SARS-CoV-2 infection represents a global health problem that has affected millions of people. The fine host immune response and its association with the…”
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Galectin-3 as a potential prognostic biomarker of severe COVID-19 in SARS-CoV-2 infected patients by Cervantes-Alvarez, Eduardo, la Rosa, Nathaly Limon-de, la Mora, Moises Salgado-de, Valdez-Sandoval, Paola, Palacios-Jimenez, Mildred, Rodriguez-Alvarez, Fatima, Vera-Maldonado, Brenda I., Aguirre-Aguilar, Eduardo, Escobar-Valderrama, Juan Manuel, Alanis-Mendizabal, Jorge, Méndez-Guerrero, Osvely, Tejeda-Dominguez, Farid, Torres-Ruíz, Jiram, Gómez-Martín, Diana, Colborn, Kathryn L., Kershenobich, David, Huang, Christene A., Navarro-Alvarez, Nalu

“…Severe COVID-19 is associated with a systemic hyperinflammatory response leading to acute respiratory distress syndrome (ARDS), multi-organ failure, and death…”
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Inflammatory myopathies and beyond: The dual role of neutrophils in muscle damage and regeneration by Torres-Ruiz, Jiram, Alcalá-Carmona, Beatriz, Alejandre-Aguilar, Ricardo, Gómez-Martín, Diana

“…Skeletal muscle is one of the most abundant tissues of the human body and is responsible for the generation of movement. Muscle injuries can lead to severe…”
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Severe COVID‐19 is marked by dysregulated serum levels of carboxypeptidase A3 and serotonin by Soria‐Castro, Rodolfo, Meneses‐Preza, Yatsiri G., Rodríguez‐López, Gloria M., Romero‐Ramírez, Sandra, Sosa‐Hernández, Víctor A., Cervantes‐Díaz, Rodrigo, Pérez‐Fragoso, Alfredo, Torres‐Ruíz, José J., Gómez‐Martín, Diana, Campillo‐Navarro, Marcia, Álvarez‐Jiménez, Violeta D., Pérez‐Tapia, Sonia M., Chávez‐Blanco, Alma D., Estrada‐Parra, Sergio, Maravillas‐Montero, José L., Chacón‐Salinas, Rommel

“…The immune response plays a critical role in the pathophysiology of SARS‐CoV‐2 infection ranging from protection to tissue damage and all occur in the…”
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Metabolomics analysis identifies glutamic acid and cystine imbalances in COVID-19 patients without comorbid conditions. Implications on redox homeostasis and COVID-19 pathophysiology by Páez-Franco, José C, Maravillas-Montero, José L, Mejía-Domínguez, Nancy R, Torres-Ruiz, Jiram, Tamez-Torres, Karla M, Pérez-Fragoso, Alfredo, Germán-Acacio, Juan Manuel, Ponce-de-León, Alfredo, Gómez-Martín, Diana, Ulloa-Aguirre, Alfredo

“…It is well known that the presence of comorbidities and age-related health issues may hide biochemical and metabolic features triggered by SARS-CoV-2 infection…”
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Clinical outcomes and risk factors for posterior reversible encephalopathy syndrome in systemic lupus erythematosus: a multicentric case–control study by Merayo-Chalico, Javier, Apodaca, Elia, Barrera-Vargas, Ana, Alcocer-Varela, Jorge, Colunga-Pedraza, Iris, González-Patiño, Alejandra, Arauz, Antonio, Abud-Mendoza, Carlos, Martínez-Martínez, Marco, Gómez-Martín, Diana

“…BackgroundPosterior reversible encephalopathy syndrome (PRES) is a well-known but rare complication in patients (<1%) with systemic lupus erythematosus (SLE)…”
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Circulating B10 regulatory cells are decreased in severe and critical COVID‐19 by Cervantes‐Díaz, Rodrigo, Sosa‐Hernández, Víctor A., Romero‐Ramírez, Sandra, Torres‐Ruiz, Jiram, Pérez‐Fragoso, Alfredo, Meza‐Sánchez, David E., Gómez‐Martín, Diana, Maravillas‐Montero, José L.

“…The contribution of B cells in COVID‐19 pathogenesis, beyond the production of specific antibodies against SARS‐CoV‐2, is still not well understood. Since one…”
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Novel Clinical, Immunological, and Metabolic Features Associated with Persistent Post-Acute COVID-19 Syndrome by Santana-de Anda, Karina, Torres-Ruiz, Jiram, Mejía-Domínguez, Nancy R, Alcalá-Carmona, Beatriz, Maravillas-Montero, José L, Páez-Franco, José Carlos, Vargas-Castro, Ana Sofía, Lira-Luna, Jaquelin, Camacho-Morán, Emmanuel A, Juarez-Vega, Guillermo, Meza-Sánchez, David, Núñez-Álvarez, Carlos, Rull-Gabayet, Marina, Gómez-Martín, Diana

“…The coronavirus disease 2019 (COVID-19) survivors are frequently observed to present persistent symptoms constituting what has been called "post-acute COVID-19…”
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Redefining COVID-19 Severity and Prognosis: The Role of Clinical and Immunobiotypes by Torres-Ruiz, Jiram, Pérez-Fragoso, Alfredo, Maravillas-Montero, José Luis, Llorente, Luis, Mejía-Domínguez, Nancy R, Páez-Franco, José Carlos, Romero-Ramírez, Sandra, Sosa-Hernández, Victor Andrés, Cervantes-Díaz, Rodrigo, Absalón-Aguilar, Abdiel, Nuñez-Aguirre, Miroslava, Juárez-Vega, Guillermo, Meza-Sánchez, David, Kleinberg-Bid, Ari, Hernández-Gilsoul, Thierry, Ponce-de-León, Alfredo, Gómez-Martín, Diana

“…Most of the explanatory and prognostic models of COVID-19 lack of a comprehensive assessment of the wide COVID-19 spectrum of abnormalities. The aim of this…”
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How GRAIL controls Treg function to maintain self-tolerance by Fathman, C Garrison, Yip, Linda, Gómez-Martín, Diana, Yu, Mang, Seroogy, Christine M, Hurt, Clarence R, Lin, Jack T, Jenks, Jennifer A, Nadeau, Kari C, Soares, Luis

“…Regulatory T cells (T ) normally maintain self-tolerance. T recognize "self" such that when they are not working properly, such as in autoimmunity, the immune…”
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Lymphopenia and autoimmunity: A double-edged sword by Merayo-Chalico, Javier, Rajme-López, Sandra, Barrera-Vargas, Ana, Alcocer-Varela, Jorge, Díaz-Zamudio, Mariana, Gómez-Martín, Diana

“…Abstract Lymphopenia is strongly associated with autoimmune diseases. The molecular mechanisms that link both phenomena are still unclear, but certain key…”
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Salivary IgA subtypes as novel disease biomarkers in systemic lupus erythematosus by Romero-Ramírez, Sandra, Sosa-Hernández, Víctor A, Cervantes-Díaz, Rodrigo, Carrillo-Vázquez, Daniel A, Meza-Sánchez, David E, Núñez-Álvarez, Carlos, Torres-Ruiz, Jiram, Gómez-Martín, Diana, Maravillas-Montero, José L

“…Immunoglobulin A (IgA) is the main antibody isotype in body fluids such as tears, intestinal mucous, colostrum, and saliva. There are two subtypes of IgA in…”
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Neutrophil Extracellular Traps Contribute to COVID-19 Hyperinflammation and Humoral Autoimmunity by Torres-Ruiz, Jiram, Absalón-Aguilar, Abdiel, Nuñez-Aguirre, Miroslava, Pérez-Fragoso, Alfredo, Carrillo-Vázquez, Daniel Alberto, Maravillas-Montero, José Luis, Mejía-Domínguez, Nancy R., Llorente, Luis, Alcalá-Carmona, Beatriz, Lira-Luna, Jaquelin, Núñez-Álvarez, Carlos, Juárez-Vega, Guillermo, Meza-Sánchez, David, Hernández-Gilsoul, Thierry, Tapia-Rodríguez, Miguel, Gómez-Martín, Diana

“…The coronavirus disease 2019 (COVID-19) is related to enhanced production of NETs, and autoimmune/autoinflammatory phenomena. We evaluated the proportion of…”
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Conformational changes in myeloperoxidase induced by ubiquitin and NETs containing free ISG15 from systemic lupus erythematosus patients promote a pro-inflammatory cytokine response in CD4 + T cells by Carrillo-Vázquez, Daniel Alberto, Jardón-Valadez, Eduardo, Torres-Ruiz, Jiram, Juárez-Vega, Guillermo, Maravillas-Montero, José Luis, Meza-Sánchez, David Eduardo, Domínguez-López, María Lilia, Varela, Jorge Carlos Alcocer, Gómez-Martín, Diana

“…Neutrophil extracellular traps (NETs) from patients with systemic lupus erythematosus (SLE) are characterized by lower ubiquitylation and myeloperoxidase (MPO)…”
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Casitas B Lineage Lymphoma b Is a Key Regulator of Peripheral Tolerance in Systemic Lupus Erythematosus by Gómez‐Martín, Diana, Ibarra‐Sánchez, María, Romo‐Tena, Jorge, Cruz‐Ruíz, José, Esparza‐López, José, Galindo‐Campos, Miguel, Díaz‐Zamudio, Mariana, Alcocer‐Varela, Jorge

“…Objective To analyze whether the expression and modulation of T cell receptor (TCR) signaling is dependent on Casitas B lineage lymphoma b (Cbl‐b) in T cells…”
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Recombinant Protein Expression and Purification of N, S1, and RBD of SARS-CoV-2 from Mammalian Cells and Their Potential Applications by García-Cordero, Julio, Mendoza-Ramírez, Juvenal, Fernández-Benavides, David, Roa-Velazquez, Daniela, Filisola-Villaseñor, Jessica, Martínez-Frías, Sandra Paola, Sanchez-Salguero, Erik Saul, Miguel-Rodríguez, Carlos E., Maravillas Montero, Jose L., Torres-Ruiz, Jose J., Gómez-Martín, Diana, Argumedo, Leopoldo Santos, Morales-Ríos, Edgar, Alvarado-Orozco, Juan M., Cedillo-Barrón, Leticia

“…The coronavirus disease 2019 (COVID-19) pandemic has reached an unprecedented level. There is a strong demand for diagnostic and serological supplies…”
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Plasmacytoid dendritic cells: Key players in viral infections and autoimmune diseases by Santana-de Anda, Karina, MD, Gómez-Martín, Diana, MD, PhD, Soto-Solís, Rodrigo, MD, Alcocer-Varela, Jorge, MD, PhD

“…Abstract Objective Describe the main activation and inhibitory pathways and receptors by which pDC regulate type I interferon secretion, as well as its…”
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CTLA-4 and autoimmunity: New insights into the dual regulator of tolerance by Romo-Tena, Jorge, Gómez-Martín, Diana, Alcocer-Varela, Jorge

“…Abstract Cytotoxic T-Lymphocye Antigen 4 (CTLA-4) or CD152 is an inhibitory molecule that plays a critical role in maintenance of tolerance to self-antigens…”
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Differential ubiquitination in NETs regulates macrophage responses in systemic lupus erythematosus by Barrera-Vargas, Ana, Gómez-Martín, Diana, Carmona-Rivera, Carmelo, Merayo-Chalico, Javier, Torres-Ruiz, Jiram, Manna, Zerai, Hasni, Sarfaraz, Alcocer-Varela, Jorge, Kaplan, Mariana J

“…To assess if ubiquitinated proteins potentially present in neutrophil extracellular traps (NETs) can modify cellular responses and induce inflammatory…”
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