Search Results - "Gómez, R Ariel"

Renin Cells, the Kidney, and Hypertension by Sequeira-Lopez, Maria Luisa S., Gomez, R. Ariel

“…Renin cells are essential for survival perfected throughout evolution to ensure normal development and defend the organism against a variety of homeostatic…”
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Renin cells in homeostasis, regeneration and immune defence mechanisms by Gomez, R. Ariel, Sequeira-Lopez, Maria Luisa S.

“…Key Points Renin-expressing cells are evolutionarily conserved and have retained features to contribute to the defence against threats to survival such as…”
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Elusive and Heterogenous Nature of Renin Cells by Almeida, Lucas F, Ariel Gomez, R, Sequeira-Lopez, Maria Luisa S

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Ctcf is required for renin expression and maintenance of the structural integrity of the kidney by Martinez, Maria Florencia, Martini, Alexandre G, Sequeira-Lopez, Maria Luisa S, Gomez, R Ariel

“…Renin cells are crucial for the regulation of blood pressure and fluid electrolyte homeostasis. We have recently shown that renin cells possess unique…”
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Local Renal Circadian Clocks Control Fluid-Electrolyte Homeostasis and BP by TOKONAMI, Natsuko, MORDASINI, David, FIRSOV, Dmitri, PRADERVAND, Sylvain, CENTENO, Gabriel, JOUFFE, Céline, MAILLARD, Marc, BONNY, Olivier, GACHON, Frédéric, ARIEL GOMEZ, R, SEQUEIRA-LOPEZ, Maria Luisa S

“…The circadian timing system is critically involved in the maintenance of fluid and electrolyte balance and BP control. However, the role of peripheral…”
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Development of the Renal Arterioles by SEQUEIRA LOPEZ, Maria Luisa S, ARIEL GOMEZ, R

“…The kidney is a highly vascularized organ that normally receives a fifth of the cardiac output. The unique spatial arrangement of the kidney vasculature with…”
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Chronic Stimulation of Renin Cells Leads to Vascular Pathology by Oka, Masafumi, Medrano, Silvia, Sequeira-Lόpez, Maria Luisa S, Gómez, R Ariel

“…Experimental or spontaneous genomic mutations of the renin–angiotensin system or its pharmacological inhibition in early life leads to renal abnormalities,…”
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Renin Cell Development: Insights From Chromatin Accessibility and Single-Cell Transcriptomics by Martini, Alexandre G., Smith, Jason P., Medrano, Silvia, Finer, Gal, Sheffield, Nathan C., Sequeira-Lopez, Maria Luisa S., Gomez, R. Ariel

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Deciphering the Identity of Renin Cells in Health and Disease by Guessoum, Omar, de Goes Martini, Alexandre, Sequeira-Lopez, Maria Luisa S., Gomez, R. Ariel

“…Hypotension and changes in fluid–electrolyte balance pose immediate threats to survival. Juxtaglomerular cells respond to such threats by increasing the…”
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Opportunities and challenges in sharing and reusing genomic interval data by Xue, Bingjie, Khoroshevskyi, Oleksandr, Gomez, R Ariel, Sheffield, Nathan C

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Renin Cell Baroreceptor, a Nuclear Mechanotransducer Central for Homeostasis by Watanabe, Hirofumi, Belyea, Brian C., Paxton, Robert L., Li, Minghong, Dzamba, Bette J., DeSimone, Douglas W., Gomez, R. Ariel, Sequeira-Lopez, Maria Luisa S.

“…[Figure: see text]…”
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Tracking the stochastic fate of cells of the renin lineage after podocyte depletion using multicolor reporters and intravital imaging by Kaverina, Natalya V, Kadoya, Hiroyuki, Eng, Diana G, Rusiniak, Michael E, Sequeira-Lopez, Maria Luisa S, Gomez, R Ariel, Pippin, Jeffrey W, Gross, Kenneth W, Peti-Peterdi, Janos, Shankland, Stuart J

“…Podocyte depletion plays a major role in focal segmental glomerular sclerosis (FSGS). Because cells of the renin lineage (CoRL) serve as adult podocyte and…”
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Renin-Expressing Cells Require β1-Integrin for Survival and for Development and Maintenance of the Renal Vasculature by Mohamed, Tahagod H., Watanabe, Hirofumi, Kaur, Rajwinderjit, Belyea, Brian C., Walker, Patrick D., Gomez, R. Ariel, Sequeira-Lopez, Maria Luisa S.

“…Juxtaglomerular cells are crucial for blood pressure and fluid-electrolyte homeostasis. The factors that maintain the life of renin cells are unknown. In vivo,…”
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A primitive type of renin-expressing lymphocyte protects the organism against infections by Belyea, Brian C., Santiago, Araceli E., Vasconez, Wilson A., Nagalakshmi, Vidya K., Xu, Fang, Mehalic, Theodore C., Sequeira-Lopez, Maria Luisa S., Gomez, R. Ariel

“…The hormone renin plays a crucial role in the regulation of blood pressure and fluid-electrolyte homeostasis. Normally, renin is synthesized by juxtaglomerular…”
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The MicroRNA-Processing Enzyme Dicer Maintains Juxtaglomerular Cells by SEQUEIRA-LOPEZ, Maria Luisa S, WEATHERFORD, Eric T, BORGES, Giulianna R, MONTEAGUDO, Maria C, PENTZ, Ellen S, HARFE, Brian D, CARRETERO, Oscar, SIGMUND, Curt D, ARIEL GOMEZ, R

“…Juxtaglomerular cells are highly specialized myoepithelioid granulated cells located in the glomerular afferent arterioles. These cells synthesize and release…”
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Genes that Confer the Identity of the Renin Cell by BRUNSKIIL, Eric W, SEQUEIRA-LOPEZ, Maria Luisa S, PENTZ, Ellen S, LIN, Eugene, JING YU, ARONOW, Bruce J, POTTER, S. Steven, ARIEL GOMEZ, R

“…Renin-expressing cells modulate BP, fluid-electrolyte homeostasis, and kidney development, but remarkably little is known regarding the genetic regulatory…”
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Patterns of differentiation of renin lineage cells during nephrogenesis by Kessel, Friederike, Steglich, Anne, Hickmann, Linda, Lira Martinez, Ricardo, Gerlach, Michael, Sequeira-Lopez, Maria Luisa S, Gomez, R Ariel, Hugo, Christian P M, Todorov, Vladimir T

“…Developmentally heterogeneous renin-expressing cells serve as progenitors for mural, glomerular, and tubular cells during nephrogenesis and are collectively…”
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Novel Functions of Renin Precursors in Homeostasis and Disease by Gomez, R Ariel, Sequeira-Lopez, Maria Luisa S

“…Renin progenitors appear early and are found in multiple tissues throughout the embryo. Besides their well known role in blood pressure and fluid homeostasis,…”
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Expression of Acsm2 , a kidney-specific gene, parallels the function and maturation of proximal tubular cells by Watanabe, Hirofumi, Paxton, Robert L, Tolerico, Matthew R, Nagalakshmi, Vidya K, Tanaka, Shinji, Okusa, Mark D, Goto, Shin, Narita, Ichiei, Watanabe, Seiji, Sequeira-Lοpez, Maria Luisa S, Gomez, R Ariel

“…The acyl-CoA synthetase medium-chain family member 2 ( ) gene was first identified and cloned by our group as a kidney-specific " " gene. However, its…”
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Vascular versus tubular renin: role in kidney development by Sequeira-Lopez, Maria Luisa S, Nagalakshmi, Vidya K, Li, Minghong, Sigmund, Curt D, Gomez, R Ariel

“…Renin, the key regulated enzyme of the renin-angiotensin system regulates blood pressure, fluid-electrolyte homeostasis, and renal morphogenesis. Whole body…”
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