Search Results - "Géminard, Charles"
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Remote Control of Insulin Secretion by Fat Cells in Drosophila
Published in Cell metabolism (01-09-2009)“…Insulin-like peptides (ILPs) couple growth, metabolism, longevity, and fertility with changes in nutritional availability. In Drosophila, several ILPs called…”
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2
Fat body glycolysis defects inhibit mTOR and promote distant muscle disorganization through TNF-α/egr and ImpL2 signaling in Drosophila larvae
Published in EMBO reports (09-09-2024)“…The fat body in Drosophila larvae functions as a reserve tissue and participates in the regulation of organismal growth and homeostasis through its endocrine…”
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3
Lipid raft-associated protein sorting in exosomes
Published in Blood (15-12-2003)“…Exosomes are small membrane vesicles secreted by cells upon fusion of multivesicular endosomes with the cell surface. The mechanisms underlying the specific…”
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4
The apical scaffold big bang binds to spectrins and regulates the growth of Drosophila melanogaster wing discs
Published in The Journal of cell biology (05-03-2018)“…During development, cell numbers are tightly regulated, ensuring that tissues and organs reach their correct size and shape. Recent evidence has highlighted…”
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5
MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis
Published in Scientific reports (11-03-2021)“…Alterations to cell polarization or to intercellular junctions are often associated with epithelial cancer progression, including breast cancers (BCa). We show…”
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6
Drosophila ALS Regulates Growth and Metabolism through Functional Interaction with Insulin-Like Peptides
Published in Cell metabolism (01-04-2008)“…In metazoans, factors of the insulin family control growth, metabolism, longevity, and fertility in response to environmental cues. In Drosophila, a family of…”
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7
Exosome Secretion: The Art of Reutilizing Nonrecycled Proteins?
Published in Traffic (Copenhagen, Denmark) (01-11-2004)“…Multivesicular bodies contain membrane vesicles which either undergo lysosomal digestion or are released in the extracellular environment as exosomes. Evidence…”
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8
Myosin1D is an evolutionarily conserved regulator of animal left–right asymmetry
Published in Nature communications (16-05-2018)“…The establishment of left–right (LR) asymmetry is fundamental to animal development, but the identification of a unifying mechanism establishing laterality…”
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9
The Atypical Cadherin Dachsous Controls Left-Right Asymmetry in Drosophila
Published in Developmental cell (22-06-2015)“…Left-right (LR) asymmetry is essential for organ development and function in metazoans, but how initial LR cue is relayed to tissues still remains unclear…”
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10
Drosophila ALS Regulates Growth and Metabolism through Functional Interaction with Insulin-like Peptides
Published in Cell metabolism (05-11-2008)Get full text
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11
Diversity and convergence in the mechanisms establishing L/R asymmetry in metazoa
Published in EMBO reports (01-09-2014)“…Differentiating left and right hand sides during embryogenesis represents a major event in body patterning. Left–Right (L/R) asymmetry in bilateria is…”
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12
Characteristics of the Interaction between Hsc70 and the Transferrin Receptor in Exosomes Released during Reticulocyte Maturation
Published in The Journal of biological chemistry (30-03-2001)“…The transferrin receptor (TfR) of reticulocytes is released in vesicular form (exosomes) during their maturation to erythrocytes. The heat shock cognate 70-kDa…”
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13
Mechanisms underlying the cooperation between loss of epithelial polarity and Notch signaling during neoplastic growth in Drosophila
Published in Development (Cambridge) (01-02-2022)“…Aggressive neoplastic growth can be initiated by a limited number of genetic alterations, such as the well-established cooperation between loss of cell…”
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14
Drosophila Left/Right Asymmetry Establishment Is Controlled by the Hox Gene Abdominal-B
Published in Developmental cell (14-01-2013)“…In Drosophila, left/right (LR) asymmetry is apparent in the directional looping of the gut and male genitalia. The dextral orientation of the organs depends on…”
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15
DE-Cadherin regulates unconventional Myosin ID and Myosin IC in Drosophila left-right asymmetry establishment
Published in Development (Cambridge) (15-05-2012)“…In bilateria, positioning and looping of visceral organs requires proper left-right (L/R) asymmetry establishment. Recent work in Drosophila has identified a…”
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Exosomes released during reticulocyte maturation bind to fibronectin via integrin α4β1
Published in European journal of biochemistry (01-01-2000)“…Exosomes are vesicles formed in the endosomal compartment and released in the extracellular medium during reticulocyte maturation into erythrocytes. They have…”
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17
The myosin ID pathway and left-right asymmetry in Drosophila
Published in Genesis (New York, N.Y. : 2000) (01-06-2014)“…Summary Drosophila is a classical model to study body patterning, however left‐right (L/R) asymmetry had remained unexplored, until recently. The discovery of…”
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18
Control of Metabolism and Growth Through Insulin-Like Peptides in Drosophila
Published in Diabetes (New York, N.Y.) (01-12-2006)“…Control of Metabolism and Growth Through Insulin-Like Peptides in Drosophila Charles Géminard , Nathalie Arquier , Sophie Layalle , Marc Bourouis , Maija…”
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Myosin1D is an evolutionarily conserved regulator of animal left–right asymmetry
Published in Nature communications (01-12-2018)Get full text
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20
Degradation of AP2 During Reticulocyte Maturation Enhances Binding of Hsc70 and Alix to a Common Site on TfR for Sorting into Exosomes
Published in Traffic (Copenhagen, Denmark) (01-03-2004)“…Reticulocytes release small membrane vesicles termed exosomes during their maturation in erythrocytes. The transferrin receptor (TfR) is completely lost from…”
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