Search Results - "Gélé, Patrick"

Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC by Do Van, Bruce, Gouel, Flore, Jonneaux, Aurélie, Timmerman, Kelly, Gelé, Patrick, Pétrault, Maud, Bastide, Michèle, Laloux, Charlotte, Moreau, Caroline, Bordet, Régis, Devos, David, Devedjian, Jean-Christophe

“…Abstract Parkinson's disease (PD) is a complex illness characterized by progressive dopaminergic neuronal loss. Several mechanisms associated with the…”
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A ferroptosis–based panel of prognostic biomarkers for Amyotrophic Lateral Sclerosis by Devos, David, Moreau, Caroline, Kyheng, Maeva, Garçon, Guillaume, Rolland, Anne Sophie, Blasco, Hélène, Gelé, Patrick, Timothée Lenglet, T., Veyrat-Durebex, C., Corcia, Philippe, Dutheil, Mary, Bede, Peter, Jeromin, Andreas, Oeckl, Patrick, Otto, Markus, Meininger, Vincent, Danel-Brunaud, Véronique, Devedjian, Jean-christophe, Duce, James A., Pradat, Pierre François

“…Accurate patient stratification into prognostic categories and targeting Amyotrophic Lateral Sclerosis (ALS)-associated pathways may pave the way for promising…”
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Long-term cognitive impairments following COVID-19: a possible impact of hypoxia by Dondaine, Thibaut, Ruthmann, Florine, Vuotto, Fanny, Carton, Louise, Gelé, Patrick, Faure, Karine, Deplanque, Dominique, Bordet, Régis

“…Background Cognitive and emotional disorders frequently persist after recovery from the acute symptoms of COVID-19; possible explanations include…”
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A pharmaco-metabolomics approach in a clinical trial of ALS: Identification of predictive markers of progression by Blasco, Hélène, Patin, Franck, Descat, Amandine, Garçon, Guillaume, Corcia, Philippe, Gelé, Patrick, Lenglet, Timothée, Bede, Peter, Meininger, Vincent, Devos, David, Gossens, Jean François, Pradat, Pierre-François

“…There is an urgent and unmet need for accurate biomarkers in Amyotrophic Lateral Sclerosis. A pharmaco-metabolomics study was conducted using plasma samples…”
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Incidence and Predictive Factors of Postprandial Hyperinsulinemic Hypoglycemia After Roux-en-Y Gastric Bypass: A Five year Longitudinal Study by Raverdy, Violeta, Baud, Gregory, Pigeyre, Marie, Verkindt, Helene, Torres, Fanelly, Preda, Cristian, Thuillier, Dorothee, Gélé, Patrick, Vantyghem, Marie-Christine, Caiazzo, Robert, Pattou, François

“…BACKGROUND:Postprandial hyperinsulinemic hypoglycemia (PHH) is often reported after Roux-en-Y gastric bypass (RYGB). In the absence of a prospective study, the…”
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Plasma amyloid levels within the Alzheimer's process and correlations with central biomarkers by Hanon, Olivier, Vidal, Jean-Sébastien, Bombois, Stéphanie, Bombois, Stéphanie, Allinquant, Bernadette, Tréluyer, Jean-Marc, Gelé, Patrick, Delmaire, Christine, Blanc, Fredéric, Buée, Luc, Touchon, Jacques, Hugon, Jacques, Vellas, Bruno, Galbrun, Evelyne, Benetos, Athanase, Berrut, Gilles, Paillaud, Elèna, Wallon, David, Castelnovo, Giovanni, Volpe-Gillot, Lisette, Paccalin, Marc, Robert, Philippe-Henri, Godefroy, Olivier, Dantoine, Thierry, Camus, Vincent, Belmin, Joël, Vandel, Pierre, Novella, Jean-Luc, Duron, Emmanuelle, Rigaud, Anne-Sophie, Schraen-Maschke, Suzanna, Gabelle, Audrey, Hanon, Olivier, Blanc, Frédéric, Boudali, Yasmina, Gabelle, Audrey, Seux, Marie–Laure, Lenoir, Hermine, Bayle, Catherine, Delbeuck, Xavier, Moulin, Florence, Latour, Florence, Plichart, Matthieu, Volpe–Gillot, Lisette, Labourée, Florien, Cassagnaud, Pascaline, Paquet, Claire, Lala, Françoise, Dumurgier, Julien, Rigaud, Anne–Sophie, Perret–Guillaume, Christine, Alonso, Eliana, du Boisgueheneuc, Foucaud, Hugonot–Diener, Laurence, Martinaud, Olivier, Boully, Clémence, Devendeville, Agnès, Robert, Philippe–Henri, Caillard, Laure, Hannequin, Didier, Sastre, Nathalie, Haffen, Sophie, Kearney–Schwartz, Anna, Novella, Jean–Luc, Deramecourt, Vincent, Chauvire, Valérie, Abitbol, Gabiel, Schwald, Nathalie, Hommet, Caroline, Cariot, Marie–Ange, Benisty, Sarah, Gherabli, Salim, Anthony, Pierre, Bloch, Frédéric, Charasz, Nathalie, Chauvelier, Sophie, Gaubert, Jean–Yves, Sacco, Guillaume, Guerin, Olivier, Boddaert, Jacques, Mackowiak, Marie–Anne, Gissot, Valérie, Picard, Candice, Gervais, Claire, Hugon, Jaques, Michel, Jean–Marc, Pariel, Sylvie, Chawakilian, Anne, Joffredo, Léna, Dupuy, Diane, Saulnier, Isabelle, Mondon, Karl, Picat, Marie–Agnès, Laurent, Marie, Daheb, Rezki, Libercier, Stéphanie, Chupin, Marie, Vidal, Jean–Sébastien, Chaussade, Edouard, Schraen-Maschke, Suzanna

“…Diagnostic relevance of plasma amyloid β (Aβ) for Alzheimer's disease (AD) process yields conflicting results. The objective of the study was to assess plasma…”
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Ceruloplasmin activity and iron chelation treatment of patients with Parkinson's disease by Grolez, Guillaume, Moreau, Caroline, Sablonnière, Bernard, Garçon, Guillaume, Devedjian, Jean-Christophe, Meguig, Sayah, Gelé, Patrick, Delmaire, Christine, Bordet, Regis, Defebvre, Luc, Cabantchik, Ioav Z, Devos, David

“…Growing body of evidence suggests that Parkinson's disease (PD) is associated with oxidative damage via iron accumulation in the substantia nigra (SN). Low…”
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On the identification of low allele frequency mosaic mutations in the brains of Alzheimer's disease patients by Sala Frigerio, Carlo, Lau, Pierre, Troakes, Claire, Deramecourt, Vincent, Gele, Patrick, Van Loo, Peter, Voet, Thierry, De Strooper, Bart

“…Abstract Introduction The cause of sporadic Alzheimer's disease (AD) remains unclear. Given the growing evidence that protein aggregates can spread in a…”
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Endothelial Dysfunction and Pre-Existing Cognitive Disorders in Stroke Patients by Mendyk-Bordet, Anne-Marie, Ouk, Thavarak, Muhr-Tailleux, Anne, Pétrault, Maud, Vallez, Emmanuelle, Gelé, Patrick, Dondaine, Thibaut, Labreuche, Julien, Deplanque, Dominique, Bordet, Régis

“…The origin of pre-existing cognitive impairment in stroke patients remains controversial, with a vascular or a degenerative hypothesis. To determine whether…”
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Plasma amyloid beta predicts conversion to dementia in subjects with mild cognitive impairment: The BALTAZAR study by Hanon, Olivier, Vidal, Jean‐Sébastien, Lehmann, Sylvain, Bombois, Stéphanie, Allinquant, Bernadette, Baret‐Rose, Christiane, Tréluyer, Jean‐Marc, Abdoul, Hendy, Gelé, Patrick, Delmaire, Christine, Blanc, Fredéric, Mangin, Jean‐François, Buée, Luc, Touchon, Jacques, Hugon, Jacques, Vellas, Bruno, Galbrun, Evelyne, Benetos, Athanase, Berrut, Gilles, Paillaud, Elena, Wallon, David, Castelnovo, Giovanni, Volpe‐Gillot, Lisette, Paccalin, Marc, Robert, Philippe, Godefroy, Olivier, Camus, Vincent, Belmin, Joël, Vandel, Pierre, Novella, Jean‐Luc, Duron, Emmanuelle, Rigaud, Anne‐Sophie, Schraen‐Maschke, Susanna, Gabelle, Audrey

“…Introduction Blood‐based biomarkers are the next challenge for Alzheimer's disease (AD) diagnosis and prognosis. Methods Mild cognitive impairment (MCI)…”
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Alkalizing Drugs Induce Accumulation of Amyloid Precursor Protein By-products in Luminal Vesicles of Multivesicular Bodies by Vingtdeux, Valérie, Hamdane, Malika, Loyens, Anne, Gelé, Patrick, Drobeck, Hervé, Bégard, Séverine, Galas, Marie-Christine, Delacourte, André, Beauvillain, Jean-Claude, Buée, Luc, Sergeant, Nicolas

“…Amyloid precursor protein (APP) metabolism is central to the pathogenesis of Alzheimer disease. We showed recently that the amyloid intracellular domain…”
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Role of neurovascular uncoupling in cognitive decline induced by metabolic disturbances: vascular explorations in a mice model by Haas, Manon, Pétrault, Maud, Ouk, Thavarak, Gelé, Patrick, Pétrault, Olivier, Bastide, Michèle

“…A link between vascular risk factors caused by metabolic disorders in mid-life and the onset of cognitive impairments has been evidenced. Our team has…”
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Role of apelin-13 in ischemic stroke under high-fat diet-induced metabolic disturbances at middle- age by Petrault, Maud, Petrault, Olivier, Ki, Vincent Berezows, Gele, Patrick, Bastide, Michèle

“…Visceral fat gain and the progressive onset of metabolic disorders in middle-aged mice induce alteration of the cerebral vascular tree in association with mild…”
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A Pilot Clinical Study on Post-Operative Recurrence Provides Biological Clues for a Role of Candida Yeasts and Fluconazole in Crohn's Disease by Sendid, Boualem, Salvetat, Nicolas, Sarter, Helène, Loridant, Severine, Cunisse, Catherine, François, Nadine, Aijjou, Rachid, Gelé, Patrick, Leroy, Jordan, Deplanque, Dominique, Jawhara, Samir, Weissmann, Dinah, Desreumaux, Pierre, Gower-Rousseau, Corinne, Colombel, Jean Frédéric, Poulain, Daniel

“…This study prompted by growing evidence of the relationship between the yeast and Crohn's disease (CD) was intended to assess the effect of a 6-month course of…”
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Author Correction: A ferroptosis–based panel of prognostic biomarkers for Amyotrophic Lateral Sclerosis by Devos, David, Moreau, Caroline, Kyheng, Maeva, Garçon, Guillaume, Rolland, Anne Sophie, Blasco, Hélène, Gelé, Patrick, Lenglet, T. Timothée, Veyrat-Durebex, C., Corcia, Philippe, Dutheil, Mary, Bede, Peter, Jeromin, Andreas, Oeckl, Patrick, Otto, Markus, Meininger, Vincent, Danel-Brunaud, Véronique, Devedjian, Jean-Christophe, Duce, James A., Pradat, Pierre François

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Nodal pathway genes are down-regulated in facial asymmetry by Nicot, Romain, Hottenstein, Molly, Raoul, Gwenael, Ferri, Joel, Horton, Michael, Tobias, John W, Barton, Elisabeth, Gelé, Patrick, Sciote, James J

“…Facial asymmetry is a common comorbid condition in patients with jaw deformation malocclusion. Heritability of malocclusion is advancing rapidly, but very…”
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Lipid-lowering drugs in the MPTP mouse model of Parkinson's disease: Fenofibrate has a neuroprotective effect, whereas bezafibrate and HMG-CoA reductase inhibitors do not by Kreisler, Alexandre, Gelé, Patrick, Wiart, Jean-François, Lhermitte, Michel, Destée, Alain, Bordet, Régis

“…Abstract We tested the ability of simvastatin, atorvastatin, fenofibrate and bezafibrate (two synthetic peroxisome proliferator-activated receptor-alpha…”
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Recovery of brain biomarkers following peroxisome proliferator-activated receptor agonist neuroprotective treatment before ischemic stroke by Gelé, Patrick, Vingtdeux, Valérie, Potey, Camille, Drobecq, Hervé, Ghestem, Antoine, Melnyk, Patricia, Buée, Luc, Sergeant, Nicolas, Bordet, Régis

“…Lipid lowering agent such as agonists of peroxisome proliferator-activated receptors (PPAR) are suggested as neuroprotective agents and may protect from the…”
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Brain ischemic preconditioning is abolished by antioxidant drugs but does not up-regulate superoxide dismutase and glutathion peroxidase by Puisieux, François, Deplanque, Dominique, Bulckaen, Hélène, Maboudou, Patrice, Gelé, Patrick, Lhermitte, Michel, Lebuffe, Gilles, Bordet, Régis

“…The present work examined the hypothesis that brain ischemic tolerance induced by ischemic preconditioning (IPC) is triggered by an initial oxidative stress…”
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The PPARα Activator Fenofibrate Slows Down the Progression of the Left Ventricular Dysfunction in Porcine Tachycardia-Induced Cardiomyopathy by Brigadeau, François, Gelé, Patrick, Wibaux, Maud, Marquié, Christelle, Martin-Nizard, Françoise, Torpier, Gérard, Fruchart, Jean-Charles, Staels, Bart, Duriez, Patrick, Lacroix, Dominique

“…It has been reported that high intramyocardial peroxisome proliferator-activated receptor α (PPARα) stimulation or overexpression altered cardiac contractile…”
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