Search Results - "Gæde, Peter"
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Plasma trimethylamine N-oxide and its metabolic precursors and risk of mortality, cardiovascular and renal disease in individuals with type 2-diabetes and albuminuria
Published in PloS one (03-03-2021)“…The trimethylamine N-oxide (TMAO) pathway is related to intestinal microbiota and has been associated to risk of cardiovascular disease (CVD). We investigated…”
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2
Home-based Intervention with Semaglutide Treatment of Neuroleptic-Related Prediabetes (HISTORI): protocol describing a prospective, randomised, placebo controlled and double-blinded multicentre trial
Published in BMJ open (18-03-2024)“…IntroductionSubjects with schizophrenia have a 2–3 fold higher mortality rate than the general population and a reduced life expectancy of 10–20 years…”
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The independent association of myocardial extracellular volume and myocardial blood flow with cardiac diastolic function in patients with type 2 diabetes: a prospective cross-sectional cohort study
Published in Cardiovascular diabetology (31-03-2023)“…Diffuse myocardial fibrosis and microvascular dysfunction are suggested to underlie cardiac dysfunction in patients with type 2 diabetes, but studies…”
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4
Reduced Myocardial Perfusion Reserve in Type 2 Diabetes Is Caused by Increased Perfusion at Rest and Decreased Maximal Perfusion During Stress
Published in Diabetes care (01-06-2020)“…To examine differences in myocardial blood flow (MBF) at rest and during stress between patients with type 2 diabetes and control subjects, and to identify…”
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Distinct non-ischemic myocardial late gadolinium enhancement lesions in patients with type 2 diabetes
Published in Cardiovascular diabetology (22-10-2020)“…Cardiovascular magnetic resonance imaging (CMR) have described localised non-ischemic late gadolinium enhancement (LGE) lesions of prognostic importance in…”
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Myocardial Blood Flow Determination From Contrast‐Free Magnetic Resonance Imaging Quantification of Coronary Sinus Flow
Published in Journal of magnetic resonance imaging (01-04-2024)“…Background Determination of myocardial blood flow (MBF) with MRI is usually performed with dynamic contrast enhanced imaging (MBFDCE). MBF can also be…”
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Adverse effects with semaglutide: a protocol for a systematic review with meta-analysis and trial sequential analysis
Published in BMJ open (21-06-2024)“…IntroductionSemaglutide is increasingly used for the treatment of type 2 diabetes mellitus, overweight and other conditions. It is well known that semaglutide…”
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Expressions of mitochondria-related genes in pregnant women with subclinical hypothyroidism, and expressions of miRNAs in maternal and cord blood
Published in Thyroid research (18-09-2023)“…Abstract Background Subclinical hypothyroidism in pregnancy and definition by upper thyrotropin (TSH) cutoff are controversial. As mitochondria are influenced…”
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Early signs of myocardial systolic dysfunction in patients with type 2 diabetes are strongly associated with myocardial microvascular dysfunction independent of myocardial fibrosis: a prospective cohort study
Published in Diabetology and metabolic syndrome (13-02-2024)“…Patients with diabetes demonstrate early left ventricular systolic dysfunction. Notably reduced global longitudinal strain (GLS) is related to poor outcomes,…”
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The effects of empagliflozin on measured glomerular filtration rate and estimated extracellular and plasma volumes in patients with type 2 diabetes
Published in Diabetes, obesity & metabolism (01-10-2023)“…Aims To investigate the effects of empagliflozin on measured glomerular filtration rate (mGFR), estimated plasma volume (PV) and estimated extracellular volume…”
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Fibroblast growth factor-23 is associated with imaging markers of diabetic cardiomyopathy and anti-diabetic therapeutics
Published in Cardiovascular diabetology (30-09-2020)“…The biomarker fibroblast growth factor-23 (FGF-23) has been associated with increased cardiovascular morbidity and mortality in both patients with and without…”
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A cost analysis of intensified vs conventional multifactorial therapy in individuals with type 2 diabetes: a post hoc analysis of the Steno-2 study
Published in Diabetologia (01-01-2019)“…Aims/hypothesis Long-term follow-up of the Steno-2 study demonstrated that intensified multifactorial intervention increased median lifespan by 7.9 years and…”
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Effects of Empagliflozin on Myocardial Flow Reserve in Patients With Type 2 Diabetes Mellitus: The SIMPLE Trial
Published in Journal of the American Heart Association (03-08-2021)“…Background Sodium–glucose cotransporter 2 inhibitors reduce hospitalizations for heart failure and cardiovascular death, although the underlying mechanisms…”
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Multifactorial Intervention and Cardiovascular Disease in Patients with Type 2 Diabetes
Published in The New England journal of medicine (30-01-2003)“…Intensified, long-term intervention reduced cardiovascular and microvascular events by half. Patients with type 2 diabetes mellitus have a risk of death from…”
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Reduction of cardiac adipose tissue volume with short‐term empagliflozin treatment in patients with type 2 diabetes: A substudy from the SIMPLE randomized clinical trial
Published in Diabetes, obesity & metabolism (01-03-2023)“…Objective Ectopic accumulation of cardiac adipose tissue volume (CAT) has been associated with cardiac remodelling and cardiac dysfunction in type 2 diabetes…”
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Prevalence of urinary incontinence among women with diabetes in the Lolland‐Falster Health Study, Denmark
Published in Neurourology and urodynamics (01-03-2021)“…Aims To investigate the prevalence of urinary incontinence (UI) and UI subtypes (stress, urgency, and mixed UI) in women with or without diabetes mellitus; and…”
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Real life evaluation of sodium-glucose cotransporter 2 inhibition in type 1 diabetes and the risk of diabetic ketoacidosis
Published in Diabetes & vascular disease research (01-09-2022)“…Background The indication for treatment of type 1 diabetes(T1D) with the sodium–glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin has been withdrawn in…”
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Impact of socioeconomic position on initiation of SGLT-2 inhibitors or GLP-1 receptor agonists in patients with type 2 diabetes – a Danish nationwide observational study
Published in The Lancet regional health. Europe (01-03-2022)“…Low socioeconomic position may affect initiation of sodium-glucose cotransporter-2 inhibitors (SGLT-2i) and glucacon-like-peptide-1 receptor agonists (GLP-1RA)…”
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Effect of empagliflozin on myocardial structure and function in patients with type 2 diabetes at high cardiovascular risk: the SIMPLE randomized clinical trial
Published in The International Journal of Cardiovascular Imaging (01-03-2022)“…To investigate the effects of 13 weeks treatment with empagliflozin in patients with high-risk type-2 diabetes mellitus on echocardiographic measures of left…”
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A multidisciplinary, shared care clinic using personalized medicine and coordinated care in patients with concomitant type 2 diabetes and cardiovascular disease. Protocol and baseline characteristics
Published in Preventive medicine reports (01-02-2024)“…Concomitant type 2 diabetes (T2DM) and cardiovascular disease (CVD) is frequent with a poor prognosis with high risk of comorbidities. Strict risk factor…”
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