Search Results - "Gázquez, Cristina"

Maturation of NAA20 Aminoterminal End Is Essential to Assemble NatB N-Terminal Acetyltransferase Complex by Lasa, Marta, Neri, Leire, Carte, Beatriz, Gázquez, Cristina, Aragón, Tomás, Aldabe, Rafael

“…Protein lifespan is regulated by co-translational modification by several enzymes, including methionine aminopeptidases and N-alpha-aminoterminal…”
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High frequency of gr/gr chromosome Y deletions in consecutive oligospermic ICSI candidates by de Llanos, Maite, Ballescà, José Luís, Gázquez, Cristina, Margarit, Ester, Oliva, Rafael

“…BACKGROUND: The Y chromosome gr/gr microdeletion eliminates two copies of the DAZ gene and several additional transcriptional units and has been associated as…”
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Utility of Urothelial mRNA Markers in Blood for Staging and Monitoring Bladder Cancer by Marín-Aguilera, Mercedes, Mengual, Lourdes, Ribal, María José, Ars, Elisabet, Ríos, José, Gázquez, Cristina, Villavicencio, Humberto, Alcaraz, Antonio

“…Objective To test the efficiency of 6 mRNA bladder markers in staging urothelial cell carcinoma (UCC) and monitoring UCC dissemination from blood samples…”
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Long-term metabolic correction of Wilson’s disease in a murine model by gene therapy by Murillo, Oihana, Luqui, Daniel Moreno, Gazquez, Cristina, Martinez-Espartosa, Debora, Navarro-Blasco, Iñigo, Monreal, Jose Ignacio, Guembe, Laura, Moreno-Cermeño, Armando, Corrales, Fernando J, Prieto, Jesus, Hernandez-Alcoceba, Ruben, Gonzalez-Aseguinolaza, Gloria

“…Graphical abstract…”
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N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB by Van Damme, Petra, Lasa, Marta, Polevoda, Bogdan, Gazquez, Cristina, Elosegui-Artola, Alberto, Kim, Duk Soo, De Juan-Pardo, Elena, Demeyer, Kimberly, Hole, Kristine, Larrea, Esther, Timmerman, Evy, Prieto, Jesus, Arnesen, Thomas, Sherman, Fred, Gevaert, Kris, Aldabe, Rafael

“…Protein N-terminal acetylation (Nt-acetylation) is an important mediator of protein function, stability, sorting, and localization. Although the responsible…”
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Protamine 2 precursors (Pre-P2), protamine 1 to protamine 2 ratio (P1/P2), and assisted reproduction outcome by de Mateo, Sara, B.S, Gázquez, Cristina, B.S, Guimerà, Marta, B.S, Balasch, Juan, M.D., Ph.D, Meistrich, Marvin L., Ph.D, Ballescà, José Luis, M.D, Oliva, Rafael, M.D., Ph.D

“…Objective To determine whether the presence of protamine 2 precursors (pre-P2/P2 ratio) and the protamine 1 to protamine 2 ratio (P1/P2) are related to the…”
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High value of 64Cu as a tool to evaluate the restoration of physiological copper excretion after gene therapy in Wilson’s disease by Murillo, Oihana, Collantes, Maria, Gazquez, Cristina, Moreno, Daniel, Hernandez-Alcoceba, Ruben, Barberia, Miren, Ecay, Margarita, Tamarit, Blanche, Douar, Anne, Ferrer, Veronica, Combal, Jean Philippe, Peñuelas, Ivan, Bénichou, Bernard, Gonzalez-Aseguinolaza, Gloria

“…Wilson’s disease (WD) is an inherited disorder of copper metabolism associated with mutations in ATP7B gene. We have shown that the administration of an…”
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Biomarkers vs conventional histological analysis to detect lymph node micrometastases in bladder cancer: a real improvement? by Gazquez, Cristina, Ribal, Maria José, Marín‐Aguilera, Mercedes, Kayed, Hany, Fernández, Pedro Luís, Mengual, Lourdes, Alcaraz, Antonio

“…Study Type – Therapy (case series) Level of Evidence 4 What's known on the subject? and What does the study add? Muscle invasive bladder cancer has a mortality…”
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A Common Protamine 1 Promoter Polymorphism (-190 C->A) Correlates With Abnormal Sperm Morphology and Increased Protamine P1/P2 Ratio in Infertile Patients by Gazquez, Cristina, Oriola, Josep, de Mateo, Sara, Vidal-Taboada, Jose M, Ballesca, Jose Luis, Oliva, Rafael

“…It is known that targeting the protamine 1 gene in mice leads to infertility, abnormal chromatin packaging, and abnormal sperm morphology. Because many…”
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Using microRNA profiling in urine samples to develop a non‐invasive test for bladder cancer by Mengual, Lourdes, Lozano, Juan José, Ingelmo‐Torres, Mercedes, Gazquez, Cristina, Ribal, María José, Alcaraz, Antonio

“…Current standard methods used to detect and monitor bladder urothelial cell carcinoma (UCC) are invasive or have low sensitivity. The incorporation into…”
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Visualization of the therapeutic efficacy of a gene correction approach in Wilson’s disease by laser-ablation inductively coupled mass spectrometry by Moreno, Daniel, Murillo, Oihana, Gazquez, Cristina, Hernandez-Alcoceba, Ruben, Uerlings, Ricarda, Gonzalez-Aseguinolaza, Gloria, Weiskirchen, Ralf

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Liver Expression of a MiniATP7B Gene Results in Long‐Term Restoration of Copper Homeostasis in a Wilson Disease Model in Mice by Murillo, Oihana, Moreno, Daniel, Gazquez, Cristina, Barberia, Miren, Cenzano, Itziar, Navarro, Iñigo, Uriarte, Iker, Sebastian, Victor, Arruebo, Manuel, Ferrer, Veronica, Bénichou, Bernard, Combal, Jean Philippe, Prieto, Jesus, Hernandez‐Alcoceba, Ruben, Gonzalez Aseguinolaza, Gloria

“…Gene therapy with an adeno‐associated vector (AAV) serotype 8 encoding the human ATPase copper‐transporting beta polypeptide (ATP7B) complementary DNA (cDNA;…”
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FRI-430-Preclinical validation of copper 64 as a translational tool for evaluating the pharmacodynamics of VTX-801 genen therapy in Wilson’s disease by González-Aseguinolaza, Gloria, Collantes, Maria, Ecay, Margarita, Moreno, Daniel, Murillo-Sauca, Oihana, Gazquez, Cristina, Ferrer, Veronica, Douar, Anne, Combal, Jean Philippe, Hernandez, Ruben, Peñuelas, Ivan, Benichou, Bernard

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Characterization of the human Nα-terminal acetyltransferase B enzymatic complex by Ametzazurra, Amagoia, Gázquez, Cristina, Lasa, Marta, Larrea, Esther, Prieto, Jesús, Aldabe, Rafael

“…BACKGROUND: Human Nα-acetyltransferase complex B (hNatB) is integrated by hNaa20p (hNAT5/hNAT3) and hNaa25p (hMDM20) proteins. Previous data have shown that…”
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NatB-mediated protein N-α-terminal acetylation is a potential therapeutic target in hepatocellular carcinoma by Neri, Leire, Lasa, Marta, Elosegui-Artola, Alberto, D'Avola, Delia, Carte, Beatriz, Gazquez, Cristina, Alve, Sara, Roca-Cusachs, Pere, Iñarrairaegui, Mercedes, Herrero, Jose, Prieto, Jesús, Sangro, Bruno, Aldabe, Rafael

“…The identification of new targets for systemic therapy of hepatocellular carcinoma (HCC) is an urgent medical need. Recently, we showed that hNatB catalyzes…”
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Characterization of the human Nalpha-terminal acetyltransferase B enzymatic complex by Ametzazurra, Amagoia, Gázquez, Cristina, Lasa, Marta, Larrea, Esther, Prieto, Jesús, Aldabe, Rafael

“…Human Nalpha-acetyltransferase complex B (hNatB) is integrated by hNaa20p (hNAT5/hNAT3) and hNaa25p (hMDM20) proteins. Previous data have shown that this…”
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164. Improvement of Gene Therapy for Wilson Disease by Murillo, Oihana, Moreno, Daniel, Gazquez, Cristina, Navarro-Blasco, Iñigo, Prieto, Jesus, Hernandez-Alcoceba, Ruben, Gonzalez-Aseguinolaza, Gloria

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Using microRNA profiling in urine samples to develop a non-invasive test for bladder cancer: miRNA profiling in urine samples by Mengual, Lourdes, Lozano, Juan José, Ingelmo-Torres, Mercedes, Gazquez, Cristina, Ribal, María José, Alcaraz, Antonio

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Molecular characterization of upper urinary tract tumours by Izquierdo, Laura, Mengual, Lourdes, Gazquez, Cristina, Ingelmo‐Torres, Mercedes, Alcaraz, Antonio

“…OBJECTIVES To assess gene‐expression patterns of BIRC5, FGFR3, IGF2, KRT20, UPK2, EBF1, CDH1, FXYD3, HTERT, TP53, AGR2, HER2 and VEGF, widely known markers of…”
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Brain copper storage after genetic long-term correction in a mouse model of Wilson disease by Uerlings, Ricarda, Moreno, Daniel, Murillo, Oihana, Gazquez, Cristina, Hernández-Alcoceba, Rubén, González-Aseguinolaza, Gloria, Weiskirchen, Ralf

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