Search Results - "Gáspárová, Zdenka"
-
1
Effect of handling on ATP utilization of cerebral Na,K-ATPase in rats with trimethyltin-induced neurodegeneration
Published in Molecular and cellular biochemistry (01-12-2021)“…Previously it was shown that for reduction of anxiety and stress of experimental animals, preventive handling seems to be one of the most effective methods…”
Get full text
Journal Article -
2
A rat-friendly modification of the non-invasive tail-cuff to record blood pressure
Published in Lab animal (01-06-2017)Get full text
Journal Article -
3
Natural substance rutin versus standard drug atorvastatin in a treatment of metabolic syndrome-like condition
Published in Saudi pharmaceutical journal (01-12-2019)“…Metabolic syndrome is a cluster of metabolic risk factors. The clear causes of its development are not known yet and there is no comprehensive treatment of…”
Get full text
Journal Article -
4
Impact of high-fat and high-fat-high-fructose diet on vessels and heart in rats with metabolic syndrome
Published in Toxicology letters (20-10-2017)Get full text
Journal Article -
5
Effect of transient ischemia on long-term potentiation of synaptic transmission in rat hippocampal slices
Published in Neuro-endocrinology letters (01-10-2008)“…Long-term potentiation (LTP) of neuronal activity in the hippocampus is thought to be a substrate for learning and memory. The influence of ischemia (IS)…”
Get more information
Journal Article -
6
Middle-aged rat hippocampus and some early changes accompanying aging
Published in Open life sciences (01-10-2012)Get full text
Journal Article -
7
The effect of venlafaxine on blood pressure and ECG in rats fed with high-fat-fructose diet
Published in Interdisciplinary toxicology (01-12-2019)“…Metabolic syndrome represents one of the major health, social and economic issues nowadays, and affects more than 25% people worldwide. Being a multifactorial…”
Get full text
Journal Article -
8
Maternal treatment of rats with the new pyridoindole antioxidant during pregnacy and lactation resulting in improved offspring hippocampal resistance to ischemia in vitro
Published in Neuro-endocrinology letters (2010)“…Damage to the developing brain may be caused by maternal environment, nutritional deficiencies, failure of protective mechanisms, etc. Further, the developing…”
Get more information
Journal Article -
9
Effect of the new pyridoindole antioxidant SMe1EC2 on functional deficits and oedema formation in rat hippocampus exposed to ischaemia in vitro
Published in Neuro-endocrinology letters (2009)“…The idea of neuroprotective therapy for ischaemic stroke is based on results from studies on experimental animal models of brain ischaemia demonstrating…”
Get more information
Journal Article -
10
The new pyridoindole antioxidant SMe1EC2 and its intervention in hypoxia/hypoglycemia-induced impairment of long-term potentiation in rat hippocampus
Published in Interdisciplinary toxicology (01-03-2011)“…Previously, the pyridoindole SMe1EC2 was proved to inhibit lipoperoxidation and carbonylation of proteins in rat brain cortex in the system Fe2+/ascorbate and…”
Get full text
Journal Article -
11
Effect of the pyridoindole SMe1EC2 and compounds affecting A(1) and A(2A) adenosine receptors in rat hippocampus under ischemia in vitro
Published in Pharmacological reports (01-05-2008)“…The effect of the newly synthesized pyridoindole antioxidant SMe1EC2 (1 micromol/l) and drugs activating or inhibiting adenosine receptors was tested under…”
Get full text
Journal Article -
12
In vivo magnetic resonance approach to trimethyltin induced neurodegeneration in rats
Published in Brain research (15-10-2017)“…•Characterization of TMT induced neurodegeneration in rats by in vivo MR.•Hippocampal tissue loss, ventricular enlargement and overall brain tissue…”
Get full text
Journal Article -
13
The new pyridoindole antioxidant SMe1EC2 and its intervention in hypoxia/hypoglycemia-induced impairment of longterm potentiation in rat hippocampus
Published in Interdisciplinary toxicology (01-03-2011)“…Previously, the pyridoindole SMe1EC2 was proved to inhibit lipoperoxidation and carbonylation of proteins in rat brain cortex in the system Fe(2+)/ascorbate…”
Get full text
Journal Article -
14
Oxidative stress induced by the Fe/ascorbic acid system or model ischemia in vitro: effect of carvedilol and pyridoindole antioxidant SMe1EC2 in young and adult rat brain tissue
Published in Interdisciplinary toxicology (01-12-2010)“…New effective strategies and new highly effective neuroprotective agents are being searched for the therapy of human stroke and cerebral ischemia. The compound…”
Get full text
Journal Article -
15
In Vitro Metabolomic Approach to Hippocampal Neurodegeneration Induced by Trimethyltin
Published in Neurochemical research (01-04-2016)“…Search for indicators of neurodegenerative disorders is a hot topic where much research remains to be done. Our aim was to determine proton nuclear magnetic…”
Get full text
Journal Article -
16
High-fructose intake-induced dyslipidemia and oxidative stress accompanied by hippocampal dysfunctions in hypertensive but not hypertriacylglycerolemic rats
Published in General physiology and biophysics (01-01-2023)“…A high-fructose intake is metabolically analogous to a high-fat diet. The impact of highfructose intake was investigated in spontaneously hypertensive (SHR)…”
Get more information
Journal Article -
17
Beneficial effect of 6 weeks lasting handling of adult rats on spatial memory in experimental model of neurodegeneration
Published in Interdisciplinary toxicology (01-10-2018)“…Handling is a form of experience which can result in physiological changes depending on the period of postnatal age when performed. There is a lot of evidence…”
Get full text
Journal Article -
18
Pyridoindole SMe1EC2 as promising agent for treating cognitive dysfunction during ageing
Published in Free radical biology & medicine (01-07-2016)Get full text
Journal Article -
19
P-19 - Pyridoindole SMe1EC2 as promising agent for treating cognitive dysfunction during ageing
Published in Free radical biology & medicine (01-07-2016)Get full text
Journal Article -
20
Progressive increase of lysosomal enzyme activities in hippocampus associated with reduction of population spike in a rat model of neurodegeneration
Published in Neuro-endocrinology letters (18-12-2016)“…Extensive effort has been made to identify early markers of neurodegeneration as late stages have no chance of treatment. Recently, many experimental models…”
Get more information
Journal Article