Search Results - "Gáspár, Krisztian"
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Rosacea Is Characterized by a Profoundly Diminished Skin Barrier
Published in Journal of investigative dermatology (01-10-2020)“…Rosacea is a common chronic inflammation of sebaceous gland–rich facial skin characterized by severe skin dryness, elevated pH, transepidermal water loss, and…”
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2
Alcohol in Psoriasis—From Bench to Bedside
Published in International journal of molecular sciences (01-05-2021)“…Alcohol affects the symptoms, compliance and comorbidities as well as the safety and efficacy of treatments in psoriatic patients. In this review, we aim to…”
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The measurement performance of the EQ-5D-5L versus EQ-5D-3L in patients with hidradenitis suppurativa
Published in Quality of life research (01-05-2021)“…Purpose Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease that affects up to 1% of the population in Europe. The EQ-5D is the most commonly…”
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Sebaceous Gland-Rich Skin Is Characterized by TSLP Expression and Distinct Immune Surveillance Which Is Disturbed in Rosacea
Published in Journal of investigative dermatology (01-05-2017)“…The microbial community exhibits remarkable diversity on topographically distinct skin regions, which may be accompanied by differences in skin immune…”
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Investigating Vα7.2 + /CD161 - T Cell and MAIT Cell Profiles Using Flow Cytometry in Healthy Subjects and Subjects with Atopic Dermatitis
Published in International journal of molecular sciences (01-03-2024)“…This study investigates the roles of mucosal-associated invariant T (MAIT) cells and Vα7.2 /CD161 T cells in skin diseases, focusing on atopic dermatitis. MAIT…”
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Antimicrobial Peptide Loss, Except for LL-37, is not Characteristic of Atopic Dermatitis
Published in Acta dermato-venereologica (30-06-2023)“…Atopic dermatitis is an inflammatory skin disease characterized by significant permeability barrier damage. Regulation and maintenance of permeability and…”
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Detection of Antimicrobial Peptides in Stratum Corneum by Mass Spectrometry
Published in International journal of molecular sciences (19-04-2021)“…Antimicrobial and immunomodulatory peptides (AMPs) are considered as the key players in the maintenance of skin barrier functions. Here, we developed a novel…”
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Regional Differences in the Permeability Barrier of the Skin—Implications in Acantholytic Skin Diseases
Published in International journal of molecular sciences (01-10-2021)“…The chemical milieu, microbiota composition, and immune activity show prominent differences in distinct healthy skin areas. The objective of the current study…”
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Immunotopographical Differences of Human Skin
Published in Frontiers in immunology (05-03-2018)“…The immunological barrier of the healthy skin is considered to be unified on the whole body surface-however, recent indirect findings have challenged this…”
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Expansion of circulating follicular T helper cells associates with disease severity in childhood atopic dermatitis
Published in Immunology letters (01-09-2017)“…Highlights • The ratio and absolute number of circulating TFH -like cells were assessed in AD. • ICOS+ TFH -like cell ratios and numbers were increased mainly…”
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Cytokine profile of the epidermis is region specific and may determine the characteristics of inflammation
Published in Experimental dermatology (01-07-2023)“…Recent data indicate that distinct skin areas show different microbial/chemical milieu. Keratinocytes (KC) respond to these stimuli by producing cytokine…”
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Resource utilization, work productivity and costs in patients with hidradenitis suppurativa: a cost-of-illness study
Published in Expert review of pharmacoeconomics & outcomes research (03-04-2022)“…Hidradenitis suppurativa (HS) is a, chronic skin disease affecting up to 1% of the population in Europe. This study aims to assess the cost-of-illness of HS…”
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13
New Data on the Features of Skin Barrier in Hidradenitis Suppurativa
Published in Biomedicines (04-01-2023)“…Hidradenitis suppurativa (HS) is a Th1/17-driven inflammatory skin disease of the apocrine gland-rich (AGR) skin regions, where keratinocytes seem to be the…”
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14
Comparison of Immune and Barrier Characteristics in Scalp and Skin Psoriasis
Published in Acta dermato-venereologica (02-07-2020)“…Abstract is missing (Short communication)…”
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15
Moderate and Severe Injuries at Five International Olympic-Style Wrestling Tournaments during 2016-2019
Published in Journal of sports science & medicine (01-03-2022)“…As a contact sport, wrestling may result in injuries. Based on the severity, they are classified as mild, moderate, severe and critical. All injuries occurring…”
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16
Investigation of Skin Barrier Functions and Allergic Sensitization in Patients with Hyper-IgE Syndrome
Published in Journal of clinical immunology (01-10-2015)“…Purpose Hyper-IgE syndrome (HIES) is a severe primary immunodeficiency, characterized by increased serum IgE levels as well as recurrent infections and atopic…”
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Myeloid but not plasmacytoid blood DCs possess Th1 polarizing and Th1/Th17 recruiting capacity in psoriasis
Published in Immunology letters (01-09-2017)“…Highlights • Psoriatic blood mDCs express CD83/CD86 maturation/activation markers. • Psoriatic blood mDCs are able to produce IL-12 Th1-polarizing cytokine. •…”
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The prevalence of obesity is increased in patients with late compared with early onset psoriasis
Published in Annals of epidemiology (01-11-2013)“…Abstract Purpose We compared the clinical and epidemiologic characteristics of early and late onset psoriasis with an emphasis on potential differences in the…”
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The chemokine receptor CCR3 participates in tissue remodeling during atopic skin inflammation
Published in Journal of dermatological science (01-07-2013)“…Abstract Background Recent studies provided insights into the recruitment and activation pathways of leukocytes in atopic dermatitis, however, the underlying…”
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Regulatory T-cell subsets with acquired functional impairment: important indicators of disease severity in atopic dermatitis
Published in Acta dermato-venereologica (01-01-2015)“…Our aim was to assess whether the presence of highly active effector T cells in atopic dermatitis (AD) is associated with changes in the number and/or function…”
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