Search Results - "Gácsi, Attila"
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Methods to Evaluate Skin Penetration In Vitro
Published in Scientia pharmaceutica (08-08-2019)“…Dermal and transdermal drug therapy is increasing in importance nowadays in drug development. To completely utilize the potential of this administration route,…”
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2
Following-up skin penetration of lidocaine from different vehicles by Raman spectroscopic mapping
Published in Journal of pharmaceutical and biomedical analysis (30-05-2018)“…•The incorporation of lidocaine in different nanocarrier systems was accomplished.•The skin penetration of novel delivery systems as lyotropic liquid crystals…”
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3
Conventional or mechanochemically-aided intercalation of diclofenac and naproxen anions into the interlamellar space of CaFe-layered double hydroxides and their application as dermal drug delivery systems
Published in Applied clay science (01-10-2021)“…The intercalation/encapsulation of the anionic forms of diclofenac and naproxen anti-inflammatory drugs into CaFe-layered double hydroxides (LDHs) were…”
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4
Formulation and investigation of hydrogels containing an increased level of diclofenac sodium using risk assessment tools
Published in European journal of pharmaceutical sciences (01-02-2024)“…Transdermal delivery of active ingredients is a challenge for pharmaceutical technology due to their inadequate penetration properties and the barrier function…”
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5
Nanostructured Lipid Carrier Gel for the Dermal Application of Lidocaine: Comparison of Skin Penetration Testing Methods
Published in Pharmaceutics (02-07-2019)“…The aim of this research was to investigate the stability of a lidocaine-loaded nanostructured lipid carrier dispersion at different temperatures, formulate a…”
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6
Novel In Vitro Investigational Methods for Modeling Skin Permeation: Skin PAMPA, Raman Mapping
Published in Pharmaceutics (25-08-2020)“…The human skin is marked as a standard by the regulatory agencies in the permeation study of dermal formulations. Artificial membranes can substitute human…”
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7
Topical Formulation of Nano Spray-Dried Levocetirizine Dihydrochloride against Allergic Edema
Published in Pharmaceutics (23-11-2022)“…Levocetirizine dihydrochloride active ingredient was microencapsulated using nano spray-drying technology for preparing microparticles containing topical gel…”
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Effects of Formulation Excipients on Skin Barrier Function in Creams Used in Pediatric Care
Published in Pharmaceutics (04-08-2020)“…Semisolid dosage forms are recommended for the dermal care of babies and children. If we look at the ingredients of these preparations, there are still many…”
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Development and Characterization of Potential Ocular Mucoadhesive Nano Lipid Carriers Using Full Factorial Design
Published in Pharmaceutics (20-07-2020)“…Generally, topically applied eye drops have low bioavailability due to short residence time and low penetration of the drug. The aim of the present study was…”
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10
Design and Optimization of Nanostructured Lipid Carrier Containing Dexamethasone for Ophthalmic Use
Published in Pharmaceutics (14-12-2019)“…The aim of this study was to perform a preformulation study of dexamethasone (DXM)-loaded nanostructured lipid carriers (NLCs) for ocular use. Lipid screening…”
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Investigation of Silicone-Containing Semisolid in Situ Film-Forming Systems Using QbD Tools
Published in Pharmaceutics (07-12-2019)“…The aim of our research work was to develop dermally applicable, semisolid film-forming systems (FFSs) containing silicones, which form a film on the skin in…”
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12
Combination of Zinc Hyaluronate and Metronidazole in a Lipid-Based Drug Delivery System for the Treatment of Periodontitis
Published in Pharmaceutics (25-03-2019)“…Despite being a highly prevalent disease and a possible contributor to adult tooth loss, periodontitis possesses no well-established therapy. The aim of the…”
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13
QbD-Based Investigation of Dermal Semisolid in situ Film-Forming Systems for Local Anaesthesia
Published in Drug design, development and therapy (01-01-2020)“…The aim of our research work was to develop dermally applicable, lidocaine hydrochloride (LID-HCl)-containing semisolid in situ film-forming systems (FFSs)…”
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Papaverine hydrochloride containing nanostructured lyotropic liquid crystal formulation as a potential drug delivery system for the treatment of erectile dysfunction
Published in Drug design, development and therapy (01-01-2018)“…Papaverine hydrochloride (PaHCl) is an old, well-known drug with spasmolytic activity but it has therapeutic effect in erectile dysfunction, too. As an…”
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15
The solubility of Ca(OH)2 in extremely concentrated NaOH solutions at 25°C
Published in Open Chemistry (01-04-2012)Get full text
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16
Synthesis and Statistical Optimization of Poly (Lactic-Co-Glycolic Acid) Nanoparticles Encapsulating GLP1 Analog Designed for Oral Delivery
Published in Pharmaceutical research (01-07-2019)“…Purpose To design and stabilize Liraglutide loaded poly (lactic-co-glycolic acid) nanoparticles (PLGA NPs) proper for oral administration. Methods PLGA NPs…”
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Comparison of the liquid and gas phase photocatalytic activity of flame-synthesized TiO2 catalysts: the role of surface quality
Published in Reaction kinetics, mechanisms and catalysis (01-04-2011)“…A set of flame-hydrolytic TiO 2 samples was synthesized. Via systematically increasing the precursor (TiCl 4 ) feeding rate to the flame, nanocrystalline TiO 2…”
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18
Stratum corneum lipid liposomes for investigating skin penetration enhancer effects
Published in RSC advances (01-01-2018)“…Knowledge of the mechanism of action of skin penetration enhancers is essential to formulators for optimizing formulations and to maximize the efficacy of…”
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19
Estimation of the solubility product of hydrocalumite–hydroxide, a layered double hydroxide with the formula of [Ca2Al(OH)6]OH·nH2O
Published in The Journal of physics and chemistry of solids (01-11-2016)“…From aqueous NaOH/Ca(OH)2/NaAl(OH)4 mixtures, after allowing short reaction times we observed the precipitation of Ca(OH)2(s) at lower, and a mixture of…”
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Some aspects of the aqueous solution chemistry of the Na+/Ca2+/OH−/Cit3− system: The structure of a new calcium citrate complex forming under hyperalkaline conditions
Published in Journal of molecular structure (15-08-2016)“…In the present study, we show that in hyperalkaline (pH > 13) aqueous solutions, Ca2+ forms a new, so far unknown complex species with the citrate ion, the…”
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