Search Results - "GÖV, Esra"

Integrative Analysis for Identification of Therapeutic Targets and Prognostic Signatures in Non-Small Cell Lung Cancer by Erkin, Özgür Cem, Cömertpay, Betül, Göv, Esra

“…Differential expressions of certain genes during tumorigenesis may serve to identify novel manageable targets in the clinic. In this work with an integrated…”
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Differential co-expression analysis reveals a novel prognostic gene module in ovarian cancer by Gov, Esra, Arga, Kazim Yalcin

“…Ovarian cancer is one of the most significant disease among gynecological disorders that women suffered from over the centuries. However, disease-specific and…”
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Cardiomyogenic differentiation potential of human lipoaspirate-derivedstem cells on hyaluronic acid/gelatin plasma gels by GÖV, Esra, KENAR, Halime, HALBUTOĞULLARI, Zehra Seda, ARĞA, Kazım Yalçın, KARAÖZ, Erdal

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Identification of key biomolecules in rheumatoid arthritis through the reconstruction of comprehensive disease-specific biological networks by Comertpay, Betul, Gov, Esra

“…Rheumatoid arthritis (RA) frequently seen chronic synovial inflammation causing joint destruction, chronic disability and reduced life expectancy. The…”
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Drug repurposing for rheumatoid arthritis: Identification of new drug candidates via bioinformatics and text mining analysis by Unal, Ulku, Comertpay, Betul, Demirtas, Talip Yasir, Gov, Esra

“…Rheumatoid arthritis (RA) is an autoimmune disease that results in the destruction of tissue by attacks on the patient by his or her own immune system. Current…”
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Biomarkers From Discovery to Clinical Application: In Silico Pre-Clinical Validation Approach in the Face of Lung Cancer by Kori, Medi, Gov, Esra, Arga, Kazim Yalcin, Sinha, Raghu

“…Clinical biomarkers, allow better classification of patients according to their disease risk, prognosis, and/or response to treatment. Although affordable…”
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Targeting the tumor stroma: integrative analysis reveal GATA2 and TORYAIP1 as novel prognostic targets in breast and ovarian cancer by Erceylan, Ömer Faruk, Savaş, Ayşe, Göv, Esra

“…Tumor stroma interaction is known to take a crucial role in cancer growth and progression. In the present study, it was performed gene expression analysis of…”
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Identification of Prognostic Biomarker Signatures and Candidate Drugs in Colorectal Cancer: Insights from Systems Biology Analysis by Rahman, Md Rezanur, Islam, Tania, Gov, Esra, Turanli, Beste, Gulfidan, Gizem, Shahjaman, Md, Banu, Nilufa Akhter, Mollah, Md Nurul Haque, Arga, Kazim Yalcin, Moni, Mohammad Ali

“…Colorectal cancer (CRC) is the second most common cause of cancer-related death in the world, but early diagnosis ameliorates the survival of CRC. This report…”
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Disclosing Potential Key Genes, Therapeutic Targets and Agents for Non-Small Cell Lung Cancer: Evidence from Integrative Bioinformatics Analysis by Mosharaf, Md Parvez, Reza, Md Selim, Gov, Esra, Mahumud, Rashidul Alam, Mollah, Md Nurul Haque

“…Non-small-cell lung cancer (NSCLC) is considered as one of the malignant cancers that causes premature death. The present study aimed to identify a few…”
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Identifying the function of methylated genes in Alzheimer’s disease to determine epigenetic signatures: a comprehensive bioinformatics analysis by Rahman, Md Rezanur, Islam, Tania, Gov, Esra, Quinn, Julian M.W., Moni, Mohammad Ali

“…Abstract Gene methylation is one means of controlling tissue gene expression, but it is unknown what pathways influencing Alzheimer’s disease (AD) are…”
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Co-expressed functional module-related genes in ovarian cancer stem cells represent novel prognostic biomarkers in ovarian cancer by Gov, Esra

“…Ovarian cancer is the leading cause of death from gynecologic malignancies. Cancer stem cells (CSC) seem to play a crucial role in tumor metastasis,…”
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Immune cell-specific and common molecular signatures in rheumatoid arthritis through molecular network approaches by Comertpay, Betul, Gov, Esra

“…Rheumatoid arthritis (RA) is an autoimmune disorder and common symptom of RA is chronic synovial inflammation. The pathogenesis of RA is not fully understood…”
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Drug Repurposing Analysis for Colorectal Cancer through Network Medicine Framework: Novel Candidate Drugs and Small Molecules by Unal, Ulku, Gov, Esra

“…This study aimed to reveal the drug-repurposing candidates for colorectal cancer (CRC) via drug-repurposing methods and network biology approaches. A novel,…”
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Bioinformatics and machine learning approach identifies potential drug targets and pathways in COVID-19 by Auwul, Md Rabiul, Rahman, Md Rezanur, Gov, Esra, Shahjaman, Md, Moni, Mohammad Ali

“…Current coronavirus disease-2019 (COVID-19) pandemic has caused massive loss of lives. Clinical trials of vaccines and drugs are currently being conducted…”
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Network medicine approaches for identification of novel prognostic systems biomarkers and drug candidates for papillary thyroid carcinoma by Kori, Medi, Temiz, Kubra, Gov, Esra

“…Papillary thyroid carcinoma (PTC) is one of the most common endocrine carcinomas worldwide and the aetiology of this cancer is still not well understood…”
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Multiomics Analysis of Tumor Microenvironment Reveals Gata2 and miRNA-124-3p as Potential Novel Biomarkers in Ovarian Cancer by Gov, Esra, Kori, Medi, Arga, Kazim Yalcin

“…Ovarian cancer is a common and, yet, one of the most deadly human cancers due to its insidious onset and the current lack of robust early diagnostic tests…”
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Bioinformatics Prediction and Machine Learning on Gene Expression Data Identifies Novel Gene Candidates in Gastric Cancer by Kori, Medi, Gov, Esra

“…Gastric cancer (GC) is one of the five most common cancers in the world and unfortunately has a high mortality rate. To date, the pathogenesis and disease…”
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Interactive cooperation and hierarchical operation of microRNA and transcription factor crosstalk in human transcriptional regulatory network by Gov, Esra, Arga, Kazim Yalcin

“…Transcriptional regulation of gene expression is an essential cellular process that is arranged by transcription factors (TFs), microRNAs (miRNA) and their…”
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Identification of molecular signatures and pathways to identify novel therapeutic targets in Alzheimer's disease: Insights from a systems biomedicine perspective by Rahman, Md. Rezanur, Islam, Tania, Zaman, Toyfiquz, Shahjaman, Md, Karim, Md. Rezaul, Huq, Fazlul, Quinn, Julian M.W., Holsinger, R.M. Damian, Gov, Esra, Moni, Mohammad Ali

“…Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the accumulation of amyloid plaques and neurofibrillary tangles in the…”
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RNA-based ovarian cancer research from 'a gene to systems biomedicine' perspective by Gov, Esra, Kori, Medi, Arga, Kazim Yalcin

“…Ovarian cancer remains the leading cause of death from a gynecologic malignancy, and treatment of this disease is harder than any other type of female…”
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