Search Results - "Fyodorov, Dmitry V."

CHD1 controls H3.3 incorporation in adult brain chromatin to maintain metabolic homeostasis and normal lifespan by Schoberleitner, Ines, Bauer, Ingo, Huang, Anming, Andreyeva, Evgeniya N., Sebald, Johanna, Pascher, Katharina, Rieder, Dietmar, Brunner, Melanie, Podhraski, Valerie, Oemer, Gregor, Cázarez-García, Daniel, Rieder, Leila, Keller, Markus A., Winkler, Robert, Fyodorov, Dmitry V., Lusser, Alexandra

“…The ATP-dependent chromatin remodeling factor CHD1 is essential for the assembly of variant histone H3.3 into paternal chromatin during sperm chromatin…”
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Independent Biological and Biochemical Functions for Individual Structural Domains of Drosophila Linker Histone H1 by Kavi, Harsh, Emelyanov, Alexander V., Fyodorov, Dmitry V., Skoultchi, Arthur I.

“…Linker histone H1 is among the most abundant components of chromatin. H1 has profound effects on chromosome architecture. H1 also helps to tether DNA- and…”
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Regulatory functions and chromatin loading dynamics of linker histone H1 during endoreplication in Drosophila by Andreyeva, Evgeniya N, Bernardo, Travis J, Kolesnikova, Tatyana D, Lu, Xingwu, Yarinich, Lyubov A, Bartholdy, Boris A, Guo, Xiaohan, Posukh, Olga V, Healton, Sean, Willcockson, Michael A, Pindyurin, Alexey V, Zhimulev, Igor F, Skoultchi, Arthur I, Fyodorov, Dmitry V

“…Eukaryotic DNA replicates asynchronously, with discrete genomic loci replicating during different stages of S phase. larval tissues undergo endoreplication…”
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Drosophila SUMM4 complex couples insulator function and DNA replication control by Andreyeva, Evgeniya N, Emelyanov, Alexander V, Nevil, Markus, Sun, Lu, Vershilova, Elena, Hill, Christina A, Keogh, Michael-C, Duronio, Robert J, Skoultchi, Arthur I, Fyodorov, Dmitry V

“…Asynchronous replication of chromosome domains during S phase is essential for eukaryotic genome function, but the mechanisms establishing which domains…”
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Emerging roles of linker histones in regulating chromatin structure and function by Fyodorov, Dmitry V., Zhou, Bing-Rui, Skoultchi, Arthur I., Bai, Yawen

“…Key Points Studies using X-ray crystallography, NMR and cryo-electron microscopy (cryo-EM) reveal that linker histones (H1) bind to nucleosomes via…”
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Phase separation drives heterochromatin domain formation by Strom, Amy R., Emelyanov, Alexander V., Mir, Mustafa, Fyodorov, Dmitry V., Darzacq, Xavier, Karpen, Gary H.

“…HP1a can nucleate into foci that display liquid properties during the early stages of heterochromatin domain formation in Drosophila embryos, suggesting that…”
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Linker histone H1 is essential for Drosophila development, the establishment of pericentric heterochromatin, and a normal polytene chromosome structure by Lu, Xingwu, Wontakal, Sandeep N, Emelyanov, Alexander V, Morcillo, Patrick, Konev, Alexander Y, Fyodorov, Dmitry V, Skoultchi, Arthur I

“…We generated mutant alleles of Drosophila melanogaster in which expression of the linker histone H1 can be down-regulated over a wide range by RNAi. When the…”
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Pet-1 ETS Gene Plays a Critical Role in 5-HT Neuron Development and Is Required for Normal Anxiety-like and Aggressive Behavior by Hendricks, Timothy J., Fyodorov, Dmitry V., Wegman, Lauren J., Lelutiu, Nadia B., Pehek, Elizabeth A., Yamamoto, Bryan, Silver, Jerry, Weeber, Edwin J., Sweatt, J.David, Deneris, Evan S.

“…The central serotonin (5-HT) neurotransmitter system is an important modulator of diverse physiological processes and behaviors; however, the transcriptional…”
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The chromodomains of CHD1 are critical for enzymatic activity but less important for chromatin localization by Morettini, Stefano, Tribus, Martin, Zeilner, Anette, Sebald, Johanna, Campo-Fernandez, Beatriz, Scheran, Gabriele, Wörle, Hildegard, Podhraski, Valerie, Fyodorov, Dmitry V, Lusser, Alexandra

“…The molecular motor protein CHD1 has been implicated in the regulation of transcription and in the transcription-independent genome-wide incorporation of H3.3…”
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Protein Complex of Drosophila ATRX/XNP and HP1a Is Required for the Formation of Pericentric Beta-heterochromatin in Vivo by Emelyanov, Alexander V., Konev, Alexander Y., Vershilova, Elena, Fyodorov, Dmitry V.

“…ATRX belongs to the family of SWI2/SNF2-like ATP-dependent nucleosome remodeling molecular motor proteins. Mutations of the human ATRX gene result in a severe…”
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Acf1 confers unique activities to ACF/CHRAC and promotes the formation rather than disruption of chromatin in vivo by Fyodorov, Dmitry V, Blower, Michael D, Karpen, Gary H, Kadonaga, James T

“…Chromatin assembly is required for the duplication of chromosomes. ACF (ATP-utilizing chromatin assembly and remodeling factor) catalyzes the ATP-dependent…”
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BEN domain protein Elba2 can functionally substitute for linker histone H1 in Drosophila in vivo by Xu, Na, Lu, Xingwu, Kavi, Harsh, Emelyanov, Alexander V., Bernardo, Travis J., Vershilova, Elena, Skoultchi, Arthur I., Fyodorov, Dmitry V.

“…Metazoan linker histones are essential for development and play crucial roles in organization of chromatin, modification of epigenetic states and regulation of…”
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APOLLO, a testis-specific Drosophila ortholog of importin-4, mediates the loading of protamine-like protein Mst77F into sperm chromatin by Emelyanov, Alexander V., Barcenilla-Merino, Daniel, Loppin, Benjamin, Fyodorov, Dmitry V.

“…DNA in sperm is packed with small, charged proteins termed SNBPs (sperm nuclear basic proteins), including mammalian and Drosophila protamines. During…”
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CenH3/CID incorporation is not dependent on the chromatin assembly factor CHD1 in Drosophila by Podhraski, Valerie, Campo-Fernandez, Beatriz, Wörle, Hildegard, Piatti, Paolo, Niederegger, Harald, Böck, Günther, Fyodorov, Dmitry V, Lusser, Alexandra

“…CHD1 is a SNF2-related ATPase that is required for the genome-wide incorporation of variant histone H3.3 in the paternal pronucleus as well as in…”
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Thioredoxin-dependent disulfide bond reduction is required for protamine eviction from sperm chromatin by Emelyanov, Alexander V, Fyodorov, Dmitry V

“…Cysteine oxidation in protamines leads to their oligomerization and contributes to sperm chromatin compaction. Here we identify the Drosophila thioredoxin…”
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Dynamics of ATP-dependent chromatin assembly by ACF by Kadonaga, James T, Fyodorov, Dmitry V

“…The assembly of DNA into chromatin is a critical step in the replication and repair of the eukaryotic genome. It has been known for nearly 20 years that…”
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Binding of Acf1 to DNA Involves a WAC Motif and Is Important for ACF-Mediated Chromatin Assembly by Fyodorov, Dmitry V., Kadonaga, James T.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Drosophila H1 Regulates the Genetic Activity of Heterochromatin by Recruitment of Su(var)3-9 by Lu, Xingwu, Wontakal, Sandeep N., Kavi, Harsh, Kim, Byung Ju, Guzzardo, Paloma M., Emelyanov, Alexander V., Xu, Na, Hannon, Gregory J., Zavadil, Jiri, Fyodorov, Dmitry V., Skoultchi, Arthur I.

“…Eukaryotic genomes harbor transposable elements and other repetitive sequences that must be silenced. Small RNA interference pathways play a major role in…”
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Drosophila TAP/p32 is a core histone chaperone that cooperates with NAP-1, NLP, and nucleophosmin in sperm chromatin remodeling during fertilization by Emelyanov, Alexander V, Rabbani, Joshua, Mehta, Monika, Vershilova, Elena, Keogh, Michael C, Fyodorov, Dmitry V

“…Nuclear DNA in the male gamete of sexually reproducing animals is organized as sperm chromatin compacted primarily by sperm-specific protamines. Fertilization…”
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CHD1 Motor Protein Is Required for Deposition of Histone Variant H3.3 into Chromatin in Vivo by Konev, Alexander Y, Tribus, Martin, Park, Sung Yeon, Podhraski, Valerie, Lim, Chin Yan, Emelyanov, Alexander V, Vershilova, Elena, Pirrotta, Vincenzo, Kadonaga, James T, Lusser, Alexandra, Fyodorov, Dmitry V

“…The organization of chromatin affects all aspects of nuclear DNA metabolism in eukaryotes. H3.3 is an evolutionarily conserved histone variant and a key…”
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