Search Results - "Futakawa, Satoshi"

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    Structural basis for specific inhibition of Autotaxin by a DNA aptamer by Kato, Kazuki, Ikeda, Hisako, Miyakawa, Shin, Futakawa, Satoshi, Nonaka, Yosuke, Fujiwara, Masatoshi, Okudaira, Shinichi, Kano, Kuniyuki, Aoki, Junken, Morita, Junko, Ishitani, Ryuichiro, Nishimasu, Hiroshi, Nakamura, Yoshikazu, Nureki, Osamu

    Published in Nature structural & molecular biology (01-05-2016)
    “…SELEX selections and crystallographic analyses have allowed development of a DNA aptamer that inhibits autotaxin with high potency and specificity, and…”
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    Anti-Angiogenic and Anti-Scarring Dual Action of an Anti-Fibroblast Growth Factor 2 Aptamer in Animal Models of Retinal Disease by Matsuda, Yusaku, Nonaka, Yosuke, Futakawa, Satoshi, Imai, Hirotaka, Akita, Kazumasa, Nishihata, Toshiaki, Fujiwara, Masatoshi, Ali, Yusuf, Bhisitkul, Robert B., Nakamura, Yoshikazu

    Published in Molecular therapy. Nucleic acids (06-09-2019)
    “…Currently approved therapies for age-related macular degeneration (AMD) are inhibitors against vascular endothelial growth factor (VEGF), which is a major…”
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    High affinity sialoside ligands of myelin associated glycoprotein by Zeng, Ying, Rademacher, Christoph, Nycholat, Corwin M., Futakawa, Satoshi, Lemme, Katrin, Ernst, Beat, Paulson, James C.

    Published in Bioorganic & medicinal chemistry letters (01-09-2011)
    “…Myelin associated glycoprotein (Siglec-4) is a myelin adhesion receptor, that is, well established for its role as an inhibitor of axonal outgrowth in nerve…”
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    Sialoside Analogue Arrays for Rapid Identification of High Affinity Siglec Ligands by Blixt, Ola, Han, Shoufa, Liao, Liang, Zeng, Ying, Hoffmann, Julia, Futakawa, Satoshi, Paulson, James C

    Published in Journal of the American Chemical Society (28-05-2008)
    “…The siglec family of sialic acid binding proteins participates in diverse cell surface biology that includes regulation of immune cell signaling and the…”
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    β-Galactoside α2,6-Sialyltransferase I Cleavage by BACE1 Enhances the Sialylation of Soluble Glycoproteins: A NOVEL REGULATORY MECHANISM FOR α2,6-SIALYLATION by Sugimoto, Ichiro, Futakawa, Satoshi, Oka, Ritsuko, Ogawa, Kazuko, Marth, Jamey D, Miyoshi, Eiji, Taniguchi, Naoyuki, Hashimoto, Yasuhiro, Kitazume, Shinobu

    Published in The Journal of biological chemistry (30-11-2007)
    “…BACE1 (β-site amyloid precursor protein-cleaving enzyme-1) is a membrane-bound aspartic protease that cleaves amyloid precursor protein to produce a neurotoxic…”
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    Molecular insights into beta -galactoside alpha 2,6-sialyltransferase secretion in vivo by Kitazume, Shinobu, Oka, Ritsuko, Ogawa, Kazuko, Futakawa, Satoshi, Hagiwara, Yoshiaki, Takikawa, Hajime, Kato, Michio, Kasahara, Akinori, Miyoshi, Eiji, Taniguchi, Naoyuki, Hashimoto, Yasuhiro

    Published in Glycobiology (Oxford) (01-05-2009)
    “…beta -Galactoside alpha 2,6-sialyltransferase (ST6Gal I), which is highly expressed in the liver, is mainly cleaved by Alzheimer's beta -site amyloid precursor…”
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    Molecular insights into β-galactoside α2,6-sialyltransferase secretion in vivo by Kitazume, Shinobu, Oka, Ritsuko, Ogawa, Kazuko, Futakawa, Satoshi, Hagiwara, Yoshiaki, Takikawa, Hajime, Kato, Michio, Kasahara, Akinori, Miyoshi, Eiji, Taniguchi, Naoyuki, Hashimoto, Yasuhiro

    Published in Glycobiology (Oxford) (01-05-2009)
    “…β-Galactoside α2,6-sialyltransferase (ST6Gal I), which is highly expressed in the liver, is mainly cleaved by Alzheimer's β-site amyloid precursor…”
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    Journal Article
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    Development of sandwich enzyme-linked immunosorbent assay systems for plasma β-galactoside α2,6-sialyltransferase, a possible hepatic disease biomarker by Futakawa, Satoshi, Kitazume, Shinobu, Oka, Ritsuko, Ogawa, Kazuko, Hagiwara, Yoshiaki, Kinoshita, Akinori, Miyashita, Kazuya, Hashimoto, Yasuhiro

    Published in Analytica chimica acta (2009)
    “…Previous reports, including our work, have shown that plasma β-galactoside α2,6-sialyltransferase (ST6Gal I) activity is significantly increased in particular…”
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    Development of sandwich enzyme-linked immunosorbent assay systems for plasma beta -galactoside alpha 2,6-sialyltransferase, a possible hepatic disease biomarker by Futakawa, Satoshi, Kitazume, Shinobu, Oka, Ritsuko, Ogawa, Kazuko, Hagiwara, Yoshiaki, Kinoshita, Akinori, Miyashita, Kazuya, Hashimoto, Yasuhiro

    Published in Analytica chimica acta (05-01-2009)
    “…Previous reports, including our work, have shown that plasma beta - galactoside alpha 2,6-sialyltransferase (ST6Gal I) activity is significantly increased in…”
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    Journal Article
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    Development of sandwich enzyme-linked immunosorbent assay systems for plasma beta-galactoside alpha2,6-sialyltransferase, a possible hepatic disease biomarker by Futakawa, Satoshi, Kitazume, Shinobu, Oka, Ritsuko, Ogawa, Kazuko, Hagiwara, Yoshiaki, Kinoshita, Akinori, Miyashita, Kazuya, Hashimoto, Yasuhiro

    Published in Analytica chimica acta (05-01-2009)
    “…Previous reports, including our work, have shown that plasma beta-galactoside alpha2,6-sialyltransferase (ST6Gal I) activity is significantly increased in…”
    Get full text
    Journal Article
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    α2,6-Sialic Acid on Platelet Endothelial Cell Adhesion Molecule (PECAM) Regulates Its Homophilic Interactions and Downstream Antiapoptotic Signaling by Shinobu Kitazume, Rie Imamaki, Kazuko Ogawa, Yusuke Komi, Satoshi Futakawa, Soichi Kojima, Yasuhiro Hashimoto, Jamey D. Marth, James C. Paulson, Naoyuki Taniguchi

    Published in The Journal of biological chemistry (26-02-2010)
    “…Antiangiogenesis therapies are now part of the standard repertoire of cancer therapies, but the mechanisms for the proliferation and survival of endothelial…”
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    β-Galactoside α2,6-Sialyltransferase I Cleavage by BACE1 Enhances the Sialylation of Soluble Glycoproteins by Ichiro Sugimoto, Satoshi Futakawa, Ritsuko Oka, Kazuko Ogawa, Jamey D. Marth, Eiji Miyoshi, Naoyuki Taniguchi, Yasuhiro Hashimoto, Shinobu Kitazume

    Published in The Journal of biological chemistry (30-11-2007)
    “…BACE1 ( β -site a myloid precursor protein- c leaving e nzyme- 1 ) is a membrane-bound aspartic protease that cleaves amyloid precursor protein to produce a…”
    Get full text
    Journal Article