Search Results - "Fussenegger, M."
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Generic object recognition with boosting
Published in IEEE transactions on pattern analysis and machine intelligence (01-03-2006)“…This paper explores the power and the limitations of weakly supervised categorization. We present a complete framework that starts with the extraction of…”
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The Impact of Mammalian Gene Regulation Concepts on Functional Genomic Research, Metabolic Engineering, and Advanced Gene Therapies
Published in Biotechnology progress (2001)“…Regulation of heterologous gene expression is of prime importance for a wide variety of basic and applied biological research areas including functional…”
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Transurethral ultrasonography-guided injection of adult autologous stem cells versus transurethral endoscopic injection of collagen in treatment of urinary incontinence
Published in World journal of urology (01-08-2007)“…In the last years preclinical studies have paved the way for the use of adult muscle derived stem cells for reconstruction of the lower urinary tract. Between…”
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Novel gene switches
Published in Handbook of experimental pharmacology (2007)“…Controlling gene activity in space and time represents a cornerstone technology in gene and cell therapeutic applications, bioengineering, drug discovery as…”
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Towards a fully synthetic substitute of alginate: Optimization of a thermal gelation/chemical cross-linking scheme ("tandem" gelation) for the production of beads and liquid-core capsules
Published in Biotechnology and bioengineering (20-12-2004)“…Fully synthetic polymers were used for the preparation of hydrogel beads and capsules, in a processing scheme that, originally designed for calcium alginate,…”
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Modeling the Quorum Sensing Regulatory Network of Human-Pathogenic Pseudomonas aeruginosa
Published in Biotechnology progress (01-05-2004)“…The biochemical network underlying quorum sensing in human‐pathogenic Pseudomonas aeruginosa is one of the best characterized. Mathematical modeling is…”
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Molecular Regulation of Cell-Cycle Progression and Apoptosis in Mammalian Cells: Implications for Biotechnology
Published in Biotechnology progress (01-11-1998)“…Regulation of the cell cycle and of programmed cell death (apoptosis) is essential for mammalian development and homeostasis. Furthermore, this regulation is…”
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Higher Productivity of Growth-Arrested Chinese Hamster Ovary Cells Expressing the Cyclin-Dependent Kinase Inhibitor p27
Published in Biotechnology progress (01-09-1998)“…We constructed stable Chinese hamster ovary (CHO) cell lines which conditionally and coordinately express the model product gene secreted alkaline phosphatase…”
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The Growth Factor Inhibitor Suramin Reduces Apoptosis and Cell Aggregation in Protein-Free CHO Cell Batch Cultures
Published in Biotechnology progress (2000)“…We have previously shown that Chinese hamster ovary (CHO) cells capable of growing in medium free of exogenous proteins die by apoptosis during all stages of a…”
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engineered mammalian band-pass network
Published in Nucleic acids research (01-10-2010)“…Gene expression circuitries, which enable cells to detect precise levels within a morphogen concentration gradient, have a pivotal impact on biological…”
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Autoregulated Multicistronic Expression Vectors Provide One-Step Cloning of Regulated Product Gene Expression in Mammalian Cells
Published in Biotechnology progress (01-11-1997)“…Regulated expression of a cloned gene often provides much higher final expression of the gene product. Also, regulated expression of an activity can enable…”
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Engineering synergy in biotechnology
Published in Nature chemical biology (01-05-2014)“…Biotechnology is a central focus in efforts to provide sustainable solutions for the provision of fuels, chemicals and materials. On the basis of a recent open…”
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Design of a novel mammalian screening system for the detection of bioavailable, non-cytotoxic streptogramin antibiotics
Published in Journal of antibiotics (01-01-2001)“…Screening and development of new antibiotic activities to counteract the increasing prevalence of multidrug-resistant (MDR) human pathogenic bacteria has once…”
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An Update of pTRIDENT Multicistronic Expression Vectors: pTRIDENTS Containing Novel Streptogramin-Responsive Promoters
Published in Biotechnology progress (01-09-2000)“…We present an update on the pTRIDENT multicistronic mammalian expression vectors and their implications in various metabolic engineering and therapeutic…”
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Object recognition using segmentation for feature detection
Published in Proceedings of the 17th International Conference on Pattern Recognition, 2004. ICPR 2004 (2004)“…A new method is presented to learn object categories from unlabeled and unsegmented images for generic object recognition. We assume that each object can be…”
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Conference Proceeding -
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Microscale tissue engineering using gravity-enforced cell assembly
Published in Trends in biotechnology (Regular ed.) (01-04-2004)“…Designing artificial microtissues by reaggregation of monodispersed primary cells, neoplastic or engineered cell lines is providing insight into cell–cell…”
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Mammalian designer cells: Engineering principles and biomedical applications
Published in Biotechnology journal (01-07-2015)“…Biotechnology is a widely interdisciplinary field focusing on the use of living cells or organisms to solve established problems in medicine, food production…”
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Hysteresis in a Synthetic Mammalian Gene Network
Published in Proceedings of the National Academy of Sciences - PNAS (05-07-2005)“…Bistable and hysteretic switches, enabling cells to adopt multiple internal expression states in response to a single external input signal, have a pivotal…”
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Mammalian synthetic biology: Engineering of sophisticated gene networks
Published in Journal of biotechnology (15-07-2007)“…With the recent development of a wide range of inducible mammalian transgene control systems it has now become possible to create functional synthetic gene…”
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