Search Results - "Fusco, Sabato"

Cell mechanosensing is regulated by substrate strain energy rather than stiffness by Panzetta, Valeria, Fusco, Sabato, Netti, Paolo A.

“…The ability of cells to perceive the mechanical identity of extracellular matrix, generally known as mechanosensing, is generally depicted as a consequence of…”
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Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties by Panciera, Tito, Citron, Anna, Di Biagio, Daniele, Battilana, Giusy, Gandin, Alessandro, Giulitti, Stefano, Forcato, Mattia, Bicciato, Silvio, Panzetta, Valeria, Fusco, Sabato, Azzolin, Luca, Totaro, Antonio, Dei Tos, Angelo Paolo, Fassan, Matteo, Vindigni, Vincenzo, Bassetto, Franco, Rosato, Antonio, Brusatin, Giovanna, Cordenonsi, Michelangelo, Piccolo, Stefano

“…Defining the interplay between the genetic events and microenvironmental contexts necessary to initiate tumorigenesis in normal cells is a central endeavour in…”
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Nutraceuticals in Pregnancy: A Special Focus on Probiotics by Perna, Angelica, Venditti, Noemi, Merolla, Francesco, Fusco, Sabato, Guerra, Germano, Zoroddu, Stefano, De Luca, Antonio, Bagella, Luigi

“…The placenta is crucial to fetal development and performs vital functions such as nutrient exchange, waste removal and hormone regulation. Abnormal placental…”
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Biocompatibility, uptake and endocytosis pathways of polystyrene nanoparticles in primary human renal epithelial cells by Monti, Daria Maria, Guarnieri, Daniela, Napolitano, Giuliana, Piccoli, Renata, Netti, Paolo, Fusco, Sabato, Arciello, Angela

“…•Polystyrene nanoparticles (44nm) are able to enter human primary renal epithelial cells.•Biocompatibility of nanoparticles has been…”
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PIP4K2B is mechanoresponsive and controls heterochromatin-driven nuclear softening through UHRF1 by Poli, Alessandro, Pennacchio, Fabrizio A., Ghisleni, Andrea, di Gennaro, Mariagrazia, Lecacheur, Margaux, Nastały, Paulina, Crestani, Michele, Pramotton, Francesca M., Iannelli, Fabio, Beznusenko, Galina, Mironov, Alexander A., Panzetta, Valeria, Fusco, Sabato, Sheth, Bhavwanti, Poulikakos, Dimos, Ferrari, Aldo, Gauthier, Nils, Netti, Paolo A., Divecha, Nullin, Maiuri, Paolo

“…Phosphatidylinositol-5-phosphate (PtdIns5P)−4-kinases (PIP4Ks) are stress-regulated phosphoinositide kinases able to phosphorylate PtdIns5P to PtdIns(4,5)P2…”
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Characterization of Hyaluronic Acid-Coated PLGA Nanoparticles by Surface-Enhanced Raman Spectroscopy by La Verde, Giuseppe, Sasso, Antonio, Rusciano, Giulia, Capaccio, Angela, Fusco, Sabato, Mayol, Laura, Biondi, Marco, Silvestri, Teresa, Netti, Paolo A, La Commara, Marco, Panzetta, Valeria, Pugliese, Mariagabriella

“…Nanoparticles (NPs) coated with hyaluronic acid (HA) seem to be increasingly promising for targeted therapy due to HA chemical versatility, which allows them…”
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Transport across the cell-membrane dictates nanoparticle fate and toxicity: a new paradigm in nanotoxicology by Guarnieri, Daniela, Sabella, Stefania, Muscetti, Ornella, Belli, Valentina, Malvindi, Maria Ada, Fusco, Sabato, De Luca, Elisa, Pompa, Pier Paolo, Netti, Paolo A

“…The toxicity of metallic nanoparticles (MNPs) has been fully ascertained, but the mechanisms underlying their cytotoxicity remain still largely unclear. Here…”
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Effect of serum proteins on polystyrene nanoparticle uptake and intracellular trafficking in endothelial cells by Guarnieri, Daniela, Guaccio, Angela, Fusco, Sabato, Netti, Paolo A.

“…The physico-chemical properties of nanoparticles (NPs), such as small dimensions, surface charge and surface functionalization, control their capability to…”
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ECM Mechanoregulation in Malignant Pleural Mesothelioma by Panzetta, Valeria, Musella, Ida, Fusco, Sabato, Netti, Paolo A

“…Malignant pleural mesothelioma is a relatively rare, but devastating tumor, because of the difficulties in providing early diagnosis and effective treatments…”
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Publisher Correction: Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties by Panciera, Tito, Citron, Anna, Di Biagio, Daniele, Battilana, Giusy, Gandin, Alessandro, Giulitti, Stefano, Forcato, Mattia, Bicciato, Silvio, Panzetta, Valeria, Fusco, Sabato, Azzolin, Luca, Totaro, Antonio, Tos, Angelo Paolo Dei, Fassan, Matteo, Vindigni, Vincenzo, Bassetto, Franco, Rosato, Antonio, Brusatin, Giovanna, Cordenonsi, Michelangelo, Piccolo, Stefano

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Impact of ionizing radiation on cell-ECM mechanical crosstalk in breast cancer by Mottareale, Rocco, Frascogna, Crescenzo, La Verde, Giuseppe, Arrichiello, Cecilia, Muto, Paolo, Netti, Paolo A, Fusco, Sabato, Panzetta, Valeria, Pugliese, Mariagabriella

“…The stiffness of the extracellular matrix plays a crucial role in cell motility and spreading, influencing cell morphology through cytoskeleton organization…”
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Cytoskeleton Response to Ionizing Radiation: A Brief Review on Adhesion and Migration Effects by La Verde, Giuseppe, Artiola, Valeria, Panzetta, Valeria, Pugliese, Mariagabriella, Netti, Paolo A., Fusco, Sabato

“…The cytoskeleton is involved in several biological processes, including adhesion, motility, and intracellular transport. Alterations in the cytoskeletal…”
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Adverse Effect of Metallic Gold and Silver Nanoparticles on Xenopus laevis Embryogenesis by Carotenuto, Rosa, Tussellino, Margherita, Fusco, Sabato, Benvenuto, Giovanna, Formiggini, Fabio, Avallone, Bice, Motta, Chiara Maria, Fogliano, Chiara, Netti, Paolo Antonio

“…Exposure to metal nanoparticles is potentially harmful, particularly when occurring during embryogenesis. In this study, we tested the effects of commercial…”
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Radiation therapy affects YAP expression and intracellular localization by modulating lamin A/C levels in breast cancer by La Verde, Giuseppe, Artiola, Valeria, Pugliese, Mariagabriella, La Commara, Marco, Arrichiello, Cecilia, Muto, Paolo, Netti, Paolo A., Fusco, Sabato, Panzetta, Valeria

“…The microenvironment of breast cancer actively participates in tumorigenesis and cancer progression. The changes observed in the architecture of the…”
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Morphological and Rheological Guided Design for the Microencapsulation Process of Lactobacillus paracasei CBA L74 in Calcium Alginate Microspheres by Di Natale, Concetta, Lagreca, Elena, Panzetta, Valeria, Gallo, Marianna, Passannanti, Francesca, Vitale, Michele, Fusco, Sabato, Vecchione, Raffaele, Nigro, Roberto, Netti, Paolo

“…The intestinal microbiota is a real ecosystem composed of several bacterial species and a very huge amount of strains that through their metabolic activities…”
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Investigation of Biophysical Migration Parameters for Normal Tissue and Metastatic Cancer Cells After Radiotherapy Treatment by Panzetta, Valeria, La Verde, Giuseppe, Pugliese, Mariagabriella, Arrichiello, Cecilia, Muto, Paolo, La Commara, Marco, D'Avino, Vittoria, Netti, Paolo A., Fusco, Sabato

“…A large body of literature has demonstrated that the mechanical properties of microenvironment have a key role in regulating cancer cell adhesion, motility,…”
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Ribonuclease/angiogenin inhibitor 1 regulates stress-induced subcellular localization of angiogenin and controls its growth and survival activities by Pizzo, Elio, Sarcinelli, Carmen, Sheng, Jinghao, Fusco, Sabato, Formiggini, Fabio, Netti, Paolo, Yu, Wenhao, D'Alessio, Giuseppe, Hu, Guo-fu

“…Angiogenin (ANG) promotes cell growth and survival. Under growth conditions, ANG undergoes nuclear translocation and is accumulated in nucleolus where it…”
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Crosstalk between focal adhesions and material mechanical properties governs cell mechanics and functions by Fusco, Sabato, Panzetta, Valeria, Embrione, Valerio, Netti, Paolo A.

“…[Display omitted] Mechanical properties of materials strongly influence cell fate and functions. Focal adhesions are involved in the extremely important…”
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Carbon quantum dots in breast cancer modulate cellular migration via cytoskeletal and nuclear structure by Dinger, Nikita, Russo, Carmela, Fusco, Sabato, Netti, Paolo A, Sirignano, Mariano, Panzetta, Valeria

“…Carbon nanomaterials have been widely applied for cutting edge therapeutic applications as they offer tunable physio-chemical properties with economic scale-up…”
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Mechanical phenotyping of cells and extracellular matrix as grade and stage markers of lung tumor tissues by Panzetta, Valeria, Musella, Ida, Rapa, Ida, Volante, Marco, Netti, Paolo A., Fusco, Sabato

“…[Display omitted] The mechanical cross-talk between cells and the extra-cellular matrix (ECM) regulates the properties, functions and healthiness of the…”
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