Search Results - "Furuya, Hirokazu"

Management of Dysphagia in Patients with Parkinson's Disease and Related Disorders by Umemoto, George, Furuya, Hirokazu

“…Various methods of rehabilitation for dysphagia have been suggested through the experience of treating stroke patients. Although most of these patients recover…”
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The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis by Imamura, Keiko, Izumi, Yuishin, Watanabe, Akira, Tsukita, Kayoko, Woltjen, Knut, Yamamoto, Takuya, Hotta, Akitsu, Kondo, Takayuki, Kitaoka, Shiho, Ohta, Akira, Tanaka, Akito, Watanabe, Dai, Morita, Mitsuya, Takuma, Hiroshi, Tamaoka, Akira, Kunath, Tilo, Wray, Selina, Furuya, Hirokazu, Era, Takumi, Makioka, Kouki, Okamoto, Koichi, Fujisawa, Takao, Nishitoh, Hideki, Homma, Kengo, Ichijo, Hidenori, Julien, Jean-Pierre, Obata, Nanako, Hosokawa, Masato, Akiyama, Haruhiko, Kaneko, Satoshi, Ayaki, Takashi, Ito, Hidefumi, Kaji, Ryuji, Takahashi, Ryosuke, Yamanaka, Shinya, Inoue, Haruhisa

“…Amyotrophic lateral sclerosis (ALS), a fatal disease causing progressive loss of motor neurons, still has no effective treatment. We developed a phenotypic…”
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Transactivation response DNA‐binding protein of 43 kDa proteinopathy and lysosomal abnormalities in spastic paraplegia type 11 by Mori, Shinichiro, Honda, Hiroyuki, Hamasaki, Hideomi, Sasagasako, Naokazu, Suzuki, Satoshi O., Furuya, Hirokazu, Taniwaki, Takayuki, Iwaki, Toru

“…Spastic paraplegia type 11 (SPG11) is the most common autosomal recessive hereditary spastic paraplegia with thinning of the corpus callosum. Spatacsin, a…”
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HLA‐B1511 is a risk factor for carbamazepine‐induced Stevens‐Johnson syndrome and toxic epidermal necrolysis in Japanese patients by Kaniwa, Nahoko, Saito, Yoshiro, Aihara, Michiko, Matsunaga, Kayoko, Tohkin, Masahiro, Kurose, Kouichi, Furuya, Hirokazu, Takahashi, Yukitoshi, Muramatsu, Masaaki, Kinoshita, Shigeru, Abe, Masamichi, Ikeda, Hiroko, Kashiwagi, Mariko, Song, Yixuan, Ueta, Mayumi, Sotozono, Chie, Ikezawa, Zenro, Hasegawa, Ryuichi

“…Summary Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life‐threatening severe cutaneous adverse reactions. Recently, strong…”
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Symmetrical glial hyperplasia in the brainstem of fibrodysplasia ossificans progressiva by Mori, Shinichiro, Suzuki, Satoshi O., Honda, Hiroyuki, Hamasaki, Hideomi, Sakae, Nobutaka, Sasagasako, Naokazu, Furuya, Hirokazu, Iwaki, Toru

“…Fibrodysplasia ossificans progressiva (FOP) is a rare autosomal dominant disease, characterized by the progressive ossification of skeletal muscles, fascia,…”
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Association of right precuneus compression with apathy in idiopathic normal pressure hydrocephalus: a pilot study by Chadani, Yoshihiro, Kashibayashi, Tetsuo, Yamamoto, Takahiro, Tsuda, Atsushi, Fujito, Ryoko, Akamatsu, Masanori, Kamimura, Naoto, Takahashi, Ryuichi, Yamagami, Takuji, Furuya, Hirokazu, Ueba, Tetsuya, Saito, Motoaki, Inoue, Keiji, Kazui, Hiroaki

“…Apathy is frequently observed in idiopathic normal pressure hydrocephalus (iNPH) and worsens cognitive impairment and gait disturbance. In this study, we…”
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An iPSC-based neural model of sialidosis uncovers glycolytic impairment-causing presynaptic dysfunction and deregulation of Ca2+ dynamics by Odaka, Haruki, Numakawa, Tadahiro, Soga, Minami, Kido, Jun, Matsumoto, Shiro, Kajihara, Ryutaro, Okumiya, Toshika, Tani, Naoki, Tanoue, Yuki, Fukuda, Takaichi, Furuya, Hirokazu, Inoue, Takafumi, Era, Takumi

“…Sialidosis is a neuropathic lysosomal storage disease caused by a deficiency in the NEU1 gene-encoding lysosomal neuraminidase and characterized by abnormal…”
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Impaired Food Transportation in Parkinson’s Disease Related to Lingual Bradykinesia by Umemoto, George, Tsuboi, Yoshio, Kitashima, Akio, Furuya, Hirokazu, Kikuta, Toshihiro

“…This study aimed to analyze quantitatively videofluoroscopic (VF) images of patients with Parkinson’s disease (PD), to evaluate if the predicted factors of the…”
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Longitudinal Changes of Tongue Thickness and Tongue Pressure in Neuromuscular Disorders by Umemoto, George, Fujioka, Shinsuke, Arahata, Hajime, Sakae, Nobutaka, Sasagasako, Naokazu, Toda, Mine, Furuya, Hirokazu, Tsuboi, Yoshio

“…Abstract Background Swallowing dysfunction is related to major cause of adverse events and an indicator of shorter survival among patients with neuromuscular…”
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Molecular epidemiology and clinical spectrum of hereditary spastic paraplegia in the Japanese population based on comprehensive mutational analyses by Ishiura, Hiroyuki, Takahashi, Yuji, Hayashi, Toshihiro, Saito, Kayoko, Furuya, Hirokazu, Watanabe, Mitsunori, Murata, Miho, Suzuki, Mikiya, Sugiura, Akira, Sawai, Setsu, Shibuya, Kazumoto, Ueda, Naohisa, Ichikawa, Yaeko, Kanazawa, Ichiro, Goto, Jun, Tsuji, Shoji

“…Hereditary spastic paraplegia (HSP) is one of the most genetically heterogeneous neurodegenerative disorders characterized by progressive spasticity and…”
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Supplemental Treatment for Huntington’s Disease with miR-132 that Is Deficient in Huntington’s Disease Brain by Fukuoka, Masashi, Takahashi, Masaki, Fujita, Hiromi, Chiyo, Tomoko, Popiel, H. Akiko, Watanabe, Shoko, Furuya, Hirokazu, Murata, Miho, Wada, Keiji, Okada, Takashi, Nagai, Yoshitaka, Hohjoh, Hirohiko

“…Huntington’s disease (HD) is an intractable neurodegenerative disorder caused by mutant Huntingtin (HTT) proteins that adversely affect various biomolecules…”
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Atypical Familial Amyotrophic Lateral Sclerosis with Slowly Progressing Lower Extremities-predominant Late-onset Muscular Weakness and Atrophy by Togawa, Jumpei, Ohi, Takekazu, Yuan, Jun-Hui, Takashima, Hiroshi, Furuya, Hirokazu, Takechi, Shinji, Fujitake, Junko, Hayashi, Saki, Ishiura, Hiroyuki, Naruse, Hiroya, Mitsui, Jun, Tsuji, Shoji

“…Objective Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by the progressive loss of the upper and lower motor…”
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Pathogenic Mutation of ALK2 Inhibits Induced Pluripotent Stem Cell Reprogramming and Maintenance: Mechanisms of Reprogramming and Strategy for Drug Identification by Hamasaki, Makoto, Hashizume, Yoshinobu, Yamada, Yoshinori, Katayama, Tomohiko, Hohjoh, Hirohiko, Fusaki, Noemi, Nakashima, Yasuharu, Furuya, Hirokazu, Haga, Nobuhiko, Takami, Yoichiro, Era, Takumi

“…Fibrodysplasia ossificans progressiva (FOP) is a rare congenital disorder characterized by progressive ossification of soft tissues. FOP is caused by mutations…”
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Drugs causing severe ocular surface involvements in Japanese patients with Stevens–Johnson syndrome/toxic epidermal necrolysis by Kaniwa, Nahoko, Ueta, Mayumi, Nakamura, Ryosuke, Okamoto-Uchida, Yoshimi, Sugiyama, Emiko, Maekawa, Keiko, Takahashi, Yukitoshi, Furuya, Hirokazu, Yagami, Akiko, Matsukura, Setsuko, Ikezawa, Zenro, Matsunaga, Kayoko, Sotozono, Chie, Aihara, Michiko, Kinoshita, Shigeru, Saito, Yoshiro

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Disease progression and phenotypes of non‐motor symptoms in Parkinson’s disease by Osaki, Yasushi, Morita, Yukari, Miyamoto, Yuka, Furushima, Tomomi, Furuta, Konosuke, Furuya, Hirokazu

“…Background Motor symptoms, non‐motor symptoms, and treatment‐related motor complications appear during the course of Parkinson's disease. Aim To observe the…”
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FALS with FUS mutation in Japan, with early onset, rapid progress and basophilic inclusion by Suzuki, Naoki, Aoki, Masashi, Warita, Hitoshi, Kato, Masaaki, Mizuno, Hideki, Shimakura, Naoko, Akiyama, Tetsuya, Furuya, Hirokazu, Hokonohara, Toshihiro, Iwaki, Akiko, Togashi, Shinji, Konno, Hidehiko, Itoyama, Yasuto

“…Mutations in the fused in sarcoma (FUS, also known as translated in liposarcoma) gene have been recently discovered to be associated with familial amyotrophic…”
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Effects of cyclodextrins on GM1-gangliosides in fibroblasts from GM1-gangliosidosis patients by Maeda, Yuki, Motoyama, Keiichi, Higashi, Taishi, Horikoshi, Yuka, Takeo, Toru, Nakagata, Naomi, Kurauchi, Yuki, Katsuki, Hiroshi, Ishitsuka, Yoichi, Kondo, Yuki, Irie, Tetsumi, Furuya, Hirokazu, Era, Takumi, Arima, Hidetoshi

“…Objectives GM1‐gangliosidosis is an inherited disorder characterized by the accumulation of GM1‐gangliosides in many tissues and organs, particularly in the…”
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Freezing of gait is an early clinical feature of progressive supranuclear palsy by Osaki, Yasushi, Morita, Yukari, Miyamoto, Yuka, Furuta, Kounosuke, Furuya, Hirokazu

“…Background and Aim Early clinical diagnosis of progressive supranuclear palsy (PSP) remains challenging. Aim We attempted to identify any sign or symptom to…”
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Dysphagia in duchenne muscular dystrophy versus myotonic dystrophy type 1 by Umemoto, George, Furuya, Hirokazu, Kitashima, Akio, Sakai, Mitsuaki, Arahata, Hajime, Kikuta, Toshihiro

“…Introduction: In this study we aimed to demonstrate the distinctive features of dysphagia in patients with myotonic dystrophy type 1 (DM1) and Duchenne…”
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New susceptibility variants to narcolepsy identified in HLA class II region by Miyagawa, Taku, Toyoda, Hiromi, Hirataka, Akane, Kanbayashi, Takashi, Imanishi, Aya, Sagawa, Yohei, Kotorii, Nozomu, Kotorii, Tatayu, Hashizume, Yuji, Ogi, Kimihiro, Hiejima, Hiroshi, Kamei, Yuichi, Hida, Akiko, Miyamoto, Masayuki, Imai, Makoto, Fujimura, Yota, Tamura, Yoshiyuki, Ikegami, Azusa, Wada, Yamato, Moriya, Shunpei, Furuya, Hirokazu, Kato, Mitsuhiro, Omata, Naoto, Kojima, Hiroto, Kashiwase, Koichi, Saji, Hiroh, Khor, Seik-Soon, Yamasaki, Maria, Wada, Yuji, Ishigooka, Jun, Kuroda, Kenji, Kume, Kazuhiko, Chiba, Shigeru, Yamada, Naoto, Okawa, Masako, Hirata, Koichi, Uchimura, Naohisa, Shimizu, Tetsuo, Inoue, Yuichi, Honda, Yutaka, Mishima, Kazuo, Honda, Makoto, Tokunaga, Katsushi

“…Narcolepsy, a sleep disorder characterized by excessive daytime sleepiness, cataplexy and rapid eye movement sleep abnormalities, is tightly associated with…”
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