Search Results - "Furuta, GT"

Eosinophils in the Esophagus-Peptic or Allergic Eosinophilic Esophagitis? Case Series of Three Patients with Esophageal Eosinophilia by NGO, Peter, FURUTA, Glenn T, ANTONIOLI, Donald A, FOX, Victor L

“…Scattered eosinophils in the distal esophagus traditionally provide the hallmark for peptic esophagitis, but the upper limit of eosinophils and the…”
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Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis by Karhausen, Jörn, Furuta, Glenn T, Tomaszewski, John E, Johnson, Randall S, Colgan, Sean P, Haase, Volker H

“…Mucosal epithelial cells are uniquely equipped to maintain barrier function even under adverse conditions. Previous studies have implicated hypoxia in mucosal…”
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Association of eosinophilic inflammation with esophageal food impaction in adults by Desai, Tusar K., Stecevic, Veslav, Chang, Chung-Ho, Goldstein, Neal S., Badizadegan, Kamran, Furuta, Glenn T.

“…Esophageal food impaction is a common presentation of eosinophilic esophagitis. The prevalence of eosinophilic esophagitis among patients with food impaction…”
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Heterogeneity in Clinical, Endoscopic, and Histologic Outcome Measures and Placebo Response Rates in Clinical Trials of Eosinophilic Esophagitis: A Systematic Review by Ma, Christopher, van Rhijn, Bram D., Jairath, Vipul, Nguyen, Tran M., Parker, Claire E., Aceves, Seema S., Furuta, Glenn T., Gupta, Sandeep K., Katzka, David A., Safroneeva, Ekaterina, Schoepfer, Alain M., Straumann, Alex, Spergel, Jonathan M., Pai, Rish K., Feagan, Brian G., Hirano, Ikuo, Dellon, Evan S., Bredenoord, Albert J.

“…Agents are being developed for treatment of eosinophilic esophagitis (EoE). However, it is not clear what outcome measures would best determine the efficacy…”
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Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis by Aherne, C M, Saeedi, B, Collins, C B, Masterson, J C, McNamee, E N, Perrenoud, L, Rapp, C R, Curtis, V F, Bayless, A, Fletcher, A, Glover, L E, Evans, C M, Jedlicka, P, Furuta, G T, de Zoeten, E F, Colgan, S P, Eltzschig, H K

“…Central to inflammatory bowel disease (IBD) pathogenesis is loss of mucosal barrier function. Emerging evidence implicates extracellular adenosine signaling in…”
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High-resolution EUS in children with eosinophilic “allergic” esophagitis by Fox, Victor L., Nurko, Samuel, Teitelbaum, Jonathan E., Badizadegan, Kamran, Furuta, Glenn T.

“…Background: The pathophysiology of dysphagia associated with eosinophilic esophagitis is unknown. This study investigated possible anatomic alterations in…”
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Eosinophils alter colonic epithelial barrier function: role for major basic protein by Furuta, Glenn T, Nieuwenhuis, Edward E S, Karhausen, Jorn, Gleich, Gerald, Blumberg, Richard S, Lee, James J, Ackerman, Steven J

“…Mucosal eosinophils increase in a number of gastrointestinal diseases that are often associated with altered epithelial barrier function, including food…”
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Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia by Furuta, G T, Turner, J R, Taylor, C T, Hershberg, R M, Comerford, K, Narravula, S, Podolsky, D K, Colgan, S P

“…Mucosal organs such as the intestine are supported by a rich and complex underlying vasculature. For this reason, the intestine, and particularly…”
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Lipid Mediator-Induced Expression of Bactericidal/Permeability-Increasing Protein (BPI) in Human Mucosal Epithelia by Canny, Geraldine, Levy, Ofer, Furuta, Glenn T., Narravula-Alipati, Sailaja, Sisson, Richard B., Serhan, Charles N., Colgan, Sean P.

“…Epithelial cells which line mucosal surfaces are the first line of defense against bacterial invasion and infection. Recent studies have also indicated that…”
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Association of Schatzki Ring With Eosinophilic Esophagitis in Children by Nurko, Samuel, Teitelbaum, Jonathan E., Husain, Khaled, Buonomo, Carlo, Fox, Victor L., Antonioli, Donald, Fortunato, Christine, Badizadegan, Kamran, Furuta, Glenn T.

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Impact of Eosinophilic Esophagitis (EoE) on Quality of Life (qol) for Youth and Their Families by Klinnert, M, Moore, W, Miller, J, Atkins, D, Fleischer, D, Furuta, G.T

“…Self-reports by pediatric patients indicate that symptoms of nausea and vomiting strongly impact their qol…”
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Dietary Adherence in Food Allergic Children with Eosinophilic Gastrointestinal Diseases by Henry, M, Atkins, D, Pan, Z, Ruybal, J, Moore, W, Furuta, G.T

“…Results described the experiences of 45 children (69% males, ages 1-18 years) with multiple food allergies (96% with >1 food allergy)…”
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Ligation of Intestinal Epithelial CD1d Induces Bioactive IL-10: Critical Role of the Cytoplasmic Tail in Autocrine Signaling by Colgan, Sean P., Hershberg, Robert M., Furuta, Glenn T., Blumberg, Richard S.

“…The intestinal epithelium is anatomically positioned to serve as the critical interface between the lumen and the mucosal immune system. In addition to MHC…”
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Allergic esophagitis in children: A clinicopathological entity by WALSH, S. V, ANTONIOLI, D. A, GOLDMAN, H, FOX, V. L, BOUSVAROS, A, LEICHTNER, A. M, FURUTA, G. T

“…Infiltration of esophageal epithelium by eosinophils is seen in reflux esophagitis and allergic gastroenteritis. This study was performed to identify…”
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Psychosocial Functioning in Children and Adolescents with Eosinophilic Esophagitis (EoE) and Their Families by Harris, R.F, Riechers, N, Furuta, G.T, Atkins, D, Klinnert, M.D

“…Reports were reviewed and rated for depression, anxiety, social functioning difficulties, sleep problems, overall psychological adjustment, and family coping…”
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Common Features of Feeding Difficulties (FD) Encountered in Children with Eosinophilic Gastrointestinal Diseases (EGIDs) by Maune, N.C, Furuta, G.T, Atkins, D, Henry, M, Pan, Z, Haas, A.M

“…An IRB approved self-administered caregiver questionnaire focusing on key features of FD was administered to consenting participants at the American…”
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Phosphorylation-Dependent Targeting of cAMP Response Element Binding Protein to the Ubiquitin/Proteasome Pathway in Hypoxia by Taylor, Cormac T., Furuta, Glenn T., Synnestvedt, Kristin, Colgan, Sean P.

“…Hypoxia activates a number of gene products through degradation of the transcriptional coactivator cAMP response element binding protein (CREB). Other…”
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A neonatal swine model for peanut allergy by Helm, Ricki M., Furuta, Glenn T., Stanley, J.Steve, Ye, Jianhui, Cockrell, Gael, Connaughton, Cathie, Simpson, Pippa, Bannon, Gary A., Burks, A.Wesley

“…Background: Peanut allergy represents a significant health threat in the United States. The factors contributing to the severity of the allergic response and…”
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Eosinophils in the Esophagus: Acid is Not the Only Cause by Furuta, Glenn T.

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Epithelial Mesenchymal Transition in Eosinophilic Esophagitis: Identification and Contributions to Esophageal Remodeling and Fibrosis by Akhtar, N, Woodruff, S.A, Mukkada, V, Fillon, S, Masterson, J, Kagalwalla, A.F, Jun, C, Lee, J.J, Furuta, G.T, Ackerman, S.J

“…Epithelial Mesenchymal Transition (EMT) is a process whereby non-motile epithelial cells de-differentiate into motile mesenchymal-like cells during chronic…”
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