Search Results - "Furusawa, Y"

LET Dependence of 8-Hydroxy-2′-deoxyguanosine (8-OHdG) Generation in Mammalian Cells under Air-Saturated and Hypoxic Conditions: A Possible Experimental Approach to the Mechanism of the Decreasing Oxygen Effect in the High-LET Region by Ito, A., Kitabatake, S., Furuichi, W., Takase, N., Nakahara, T., Akiyama, T., Yoshida, S., Kusano, Y., Furusawa, Y., Hirayama, R.

“…One of the most distinguished features in biological effects of heavy ions would be the decrease of oxygen effect in the high-LET region. This feature has been…”
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Radiobiological description of the LET dependence of the cell survival of oxic and anoxic cells irradiated by carbon ions by Antonovic, L., Brahme, A., Furusawa, Y., Toma-Dasu, I.

“…Light-ion radiation therapy against hypoxic tumors is highly curative due to reduced dependence on the presence of oxygen in the tumor at elevated linear…”
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BYSTANDER WI-38 CELLS MODULATE DNA DOUBLE-STRAND BREAK REPAIR IN MICROBEAM-TARGETED A549 CELLS THROUGH GAP JUNCTION INTERCELLULAR COMMUNICATION by Kobayashi, A, Autsavapromporn, N, Ahmad, T A F Tengku, Oikawa, M, Homma-Takeda, S, Furusawa, Y, Wang, J, Konishi, T

“…Bi-directional signaling involved in radiation-induced bystander effect (RIBE) between irradiated carcinoma cells and their surrounding non-irradiated normal…”
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DOSE-RATE AND CELL-KILLING SENSITIVITY OF HIGH-LINEAR ENERGY TRANSFER ION BEAM by Furusawa, Y, Matsumoto, Y, Hirayama, R, Ohsawa, D, Konishi, T

“…It is believed that the dose-rate of radiation will have an influence on cell sensitivity. The dose-rate effects on cell survival can be expressed by the…”
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Clinical oxygen enhancement ratio of tumors in carbon ion radiotherapy: the influence of local oxygenation changes by Antonovic, Laura, Lindblom, Emely, Dasu, Alexandru, Bassler, Niels, Furusawa, Yoshiya, Toma-Dasu, Iuliana

“…The effect of carbon ion radiotherapy on hypoxic tumors has recently been questioned because of low linear energy transfer (LET) values in the spread-out Bragg…”
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Microdosimetric calculation of relative biological effectiveness for design of therapeutic proton beams by Kase, Yuki, Yamashita, Wataru, Matsufuji, Naruhiro, Takada, Kenta, Sakae, Takeji, Furusawa, Yoshiya, Yamashita, Haruo, Murayama, Shigeyuki

“…The authors attempt to establish the relative biological effectiveness (RBE) calculation for designing therapeutic proton beams on the basis of microdosimetry…”
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Role of isolated and clustered DNA damage and the post-irradiating repair process in the effects of heavy ion beam irradiation by Tokuyama, Yuka, Furusawa, Yoshiya, Ide, Hiroshi, Yasui, Akira, Terato, Hiroaki

“…Clustered DNA damage is a specific type of DNA damage induced by ionizing radiation. Any type of ionizing radiation traverses the target DNA molecule as a…”
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Nitric oxide-mediated bystander effect induced by heavy-ions in human salivary gland tumour cells by Shao, C., Furusawa, Y., Aoki, M., Matsumoto, H., Ando, K.

“…Purpose : To investigate the signal factor and its function in the medium-mediated bystander effect during heavy-ion irradiation of human salivary gland (HSG)…”
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Analysis of cell-survival fractions for heavy-ion irradiations based on microdosimetric kinetic model implemented in the particle and heavy ion transport code system by Sato, T, Watanabe, R, Kase, Y, Tsuruoka, C, Suzuki, M, Furusawa, Y, Niita, K

“…It is considered that the linear energy transfer (LET) may not be the ideal index for expressing the relative biological effectiveness (RBE) of cell killing…”
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Migration area of the Tsushima Warm Current Branches within the Sea of Japan: Implications from transport of 228Ra by Inoue, M., Shirotani, Y., Furusawa, Y., Fujimoto, K., Kofuji, H., Yoshida, K., Nagao, S., Yamamoto, M., Hamajima, Y., Honda, N., Morimoto, A., Takikawa, T., Shiomoto, A., Isoda, Y., Minakawa, M.

“…We investigated lateral profiles of 228Ra (half-life; 5.75 years) activity and 228Ra/226Ra (1600 years) activity ratio using 241 surface water samples…”
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Inactivation of aerobic and hypoxic cells from three different cell lines by accelerated (3)He-, (12)C- and (20)Ne-ion beams by Furusawa, Y, Fukutsu, K, Aoki, M, Itsukaichi, H, Eguchi-Kasai, K, Ohara, H, Yatagai, F, Kanai, T, Ando, K

“…The LET-RBE spectra for cell killing for cultured mammalian cells exposed to accelerated heavy ions were investigated to design a spread-out Bragg peak beam…”
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109: New challenges for biologically adapted ion beam treatment planning: single and multi-ion approaches by Krämer, M, Durante, M, Furusawa, Y, Hirayama, R, Scifoni, E, Tinganelli, W

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Delivery mechanism of (134)Cs and (137)Cs in seawater off the Sanriku Coast, Japan, following the Fukushima Dai-ichi NPP accident by Inoue, M, Kofuji, H, Fujimoto, K, Furusawa, Y, Yoshida, K, Nagao, S, Yamamoto, M, Hamajima, Y, Minakawa, M

“…To assess the delivery mechanism of radiocesium emitted from the Fukushima Dai-ichi Nuclear Power Plant (FDNPP), we examined vertical profiles of (134)Cs,…”
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In vivo radiobiological assessment of the new clinical carbon ion beams at CNAO by Facoetti, A, Vischioni, B, Ciocca, M, Ferrarini, M, Furusawa, Y, Mairani, A, Matsumoto, Y, Mirandola, A, Molinelli, S, Uzawa, A, Vilches, Freixas G, Orecchia, R

“…In this article, the in vivo study performed to evaluate the uniformity of biological doses within an hypothetical target volume and calculate the values of…”
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Delivery mechanism of 134Cs and 137Cs in seawater off the Sanriku Coast, Japan, following the Fukushima Dai-ichi NPP accident by Inoue, M., Kofuji, H., Fujimoto, K., Furusawa, Y., Yoshida, K., Nagao, S., Yamamoto, M., Hamajima, Y., Minakawa, M.

“…To assess the delivery mechanism of radiocesium emitted from the Fukushima Dai-ichi Nuclear Power Plant (FDNPP), we examined vertical profiles of 134Cs, 137Cs,…”
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Heavy ion radiation up-regulates Cx43 and ameliorates arrhythmogenic substrates in hearts after myocardial infarction by AMINO, Mari, YOSHIOKA, Koichiro, YASUI, Kenji, KAMIYA, Kaichiro, KODAMA, Itsuo, TANABE, Teruhisa, TANAKA, Etsuro, MORI, Hidezo, FURUSAWA, Yoshiya, ZAREBA, Wojciech, YAMAZAKI, Masatoshi, NAKAGAWA, Harumichi, HONJO, Haruo

“…Radiation has been shown to enhance intercellular communication in the skin and lungs through an increase of connexin43 (Cx43) expression. If analogous Cx43…”
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Side of symptom onset not affects freezing of gait in Parkinson's disease by Bando, K, Sato, F, Furusawa, Y, Kobayashi, Y, Murata, M

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2029 POSTER Biological Quality Assurance of Carbon-ion Beam Irradiation at Spread-out Bragg Peak (SOBP) Beams by Takahashi, T, Yoshida, Y, Musha, A, Ando, K, Furusawa, Y, Kanai, T, Murata, K, Takahashi, A, Ohno, T, Nakano, T

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RBE and OER within the spread-out Bragg peak for proton beam therapy: in vitro study at the Proton Medical Research Center at the University of Tsukuba by Kanemoto, Ayae, Hirayama, Ryoichi, Moritake, Takashi, Furusawa, Yoshiya, Sun, Lue, Sakae, Takeji, Kuno, Akihiro, Terunuma, Toshiyuki, Yasuoka, Kiyoshi, Mori, Yutaro, Tsuboi, Koji, Sakurai, Hideyuki

“…There are few reports on the biological homogeneity within the spread-out Bragg peak (SOBP) of proton beams. Therefore, to evaluate the relative biological…”
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Mammalian cells loaded with platinum-containing molecules are sensitized to fast atomic ions by Usami, N., Furusawa, Y., Kobayashi, K., Lacombe, S., Reynaud-Angelin, A., Sage, E., Wu, Ting-Di, Croisy, A., Guerquin-Kern, J-L., Le Sech, C.

“…Purpose: This work investigates whether a synergy in cell death induction exists in combining atomic ions irradiation and addition of platinum salts. Such a…”
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