Search Results - "Furtado Mosqueira, Vanessa Carla"

Nanotechnology applied to the treatment of malaria by Santos-Magalhães, Nereide Stela, Mosqueira, Vanessa Carla Furtado

“…Despite the fact that we live in an era of advanced technology and innovation, infectious diseases, like malaria, continue to be one of the greatest health…”
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Mechanisms of artemether toxicity on single cardiomyocytes and protective effect of nanoencapsulation by Moreira Souza, Ana Carolina, Grabe‐Guimarães, Andrea, Cruz, Jader dos Santos, Santos‐Miranda, Artur, Farah, Charlotte, Teixeira Oliveira, Liliam, Lucas, Alexandre, Aimond, Franck, Sicard, Pierre, Mosqueira, Vanessa Carla Furtado, Richard, Sylvain

“…Background and Purpose The artemisinin derivative, artemether, has antimalarial activity with potential neurotoxic and cardiotoxic effects. Artemether in…”
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Photodynamic therapy with the dual-mode association of IR780 to PEG-PLA nanocapsules and the effects on human breast cancer cells by Machado, Marina Guimarães Carvalho, de Oliveira, Maria Alice, Lanna, Elisa Gomes, Siqueira, Raoni Pais, Pound-Lana, Gwenaelle, Branquinho, Renata Tupinambá, Mosqueira, Vanessa Carla Furtado

“…IR780 is a near-infrared fluorescent dye, which can be applied as a photosensitizer in photodynamic (PDT) and photothermal (PTT) therapies and as a…”
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Lipid-based nanocarriers co-loaded with artemether and triglycerides of docosahexaenoic acid: Effects on human breast cancer cells by Lanna, Elisa Gomes, Siqueira, Raoni Pais, Machado, Marina Guimarães Carvalho, de Souza, Aline, Trindade, Izabel Cristina, Branquinho, Renata Tupinambá, Mosqueira, Vanessa Carla Furtado

“…[Display omitted] •Lipid-nanocarriers improve the activity of artemether and DHA in human breast cancer cells.•Artemether and docosahexaenoic acid increased…”
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Mechanistic insights into the intracellular release of doxorubicin from pH-sensitive liposomes by dos Reis, Samara Bonesso, de Oliveira Silva, Juliana, Garcia-Fossa, Fernanda, Leite, Elaine Amaral, Malachias, Angelo, Pound-Lana, Gwenaelle, Mosqueira, Vanessa Carla Furtado, Oliveira, Mônica Cristina, de Barros, André Luís Branco, de Jesus, Marcelo Bispo

“…[Display omitted] •The release from pH-sensitive liposomes is more complex than only intraluminal pH decreases.•pH-sensitive liposomes released doxorubicin…”
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In vitro interaction of polyethylene glycol-block-poly(D,L-lactide) nanocapsule devices with host cardiomyoblasts and Trypanosoma cruzi-infective forms by Siqueira, Raoni Pais, Milagre, Matheus Marques, de Oliveira, Maria Alice, Branquinho, Renata Tupinambá, Torchelsen, Fernanda Karoline Vieira, de Lana, Marta, Machado, Marina Guimarães Carvalho, Andrade, Margareth Spangler, Bahia, Maria Terezinha, Mosqueira, Vanessa Carla Furtado

“…Chagas disease, caused by the protozoan Trypanosoma cruzi , is an important public health problem in Latin America. Nanoencapsulation of anti- T. cruzi drugs…”
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Increased Body Exposure to New Anti-Trypanosomal Through Nanoencapsulation by Tupinambá Branquinho, Renata, Pound-Lana, Gwenaelle, Marques Milagre, Matheus, Saúde-Guimarães, Dênia Antunes, Vilela, José Mário Carneiro, Spangler Andrade, Margareth, de Lana, Marta, Mosqueira, Vanessa Carla Furtado

“…Lychnopholide, a lipophilic sesquiterpene lactone, is efficacious in mice at the acute and chronic phases of Chagas disease. Conventional poly-ε-caprolactone…”
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Polymeric nanocapsules prevent oxidation of core-loaded molecules: evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation by Roy, Jérôme, Oliveira, Liliam Teixeira, Oger, Camille, Galano, Jean-Marie, Bultel-Poncé, Valerie, Richard, Sylvain, Guimaraes, Andrea Grabe, Vilela, José Mário Carneiro, Andrade, Margareth Spangler, Durand, Thierry, Besson, Pierre, Mosqueira, Vanessa Carla Furtado, Le Guennec, Jean-Yves

“…Nanocapsules, as a delivery system, are able to target drugs and other biologically sensitive molecules to specific cells or organs. This system has been…”
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Relationship between complement activation, cellular uptake and surface physicochemical aspects of novel PEG-modified nanocapsules by Mosqueira, Vanessa Carla Furtado, Legrand, Philippe, Gulik, Annette, Bourdon, Olivier, Gref, Ruxandra, Labarre, Denis, Barratt, Gillian

“…The aim of our work was to examine the relationship between modifications of the surface of nanocapsules (NC) by adsorption or covalent grafting of…”
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Repositioning of Tamoxifen in Surface-Modified Nanocapsules as a Promising Oral Treatment for Visceral Leishmaniasis by Silva, Débora Faria, Reis, Levi Eduardo Soares, Machado, Marina Guimarães Carvalho, Dophine, Douglas Daniel, de Andrade, Vinicius Roberto, de Lima, Wanderson Geraldo, Andrade, Margareth Spangler, Vilela, José Mário Carneiro, Reis, Alexandre Barbosa, Pound-Lana, Gwenaelle, Rezende, Simone Aparecida, Mosqueira, Vanessa Carla Furtado

“…Standards of care for human visceral leishmaniasis (VL) are based on drugs used parenterally, and oral treatment options are urgently needed. In the present…”
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Benznidazole self-emulsifying delivery system: A novel alternative dosage form for Chagas disease treatment by Mazzeti, Ana Lia, Oliveira, Liliam Teixeira, Gonçalves, Karolina R., Schaun, Géssica C., Mosqueira, Vanessa Carla Furtado, Bahia, Maria Terezinha

“…Benznidazole (BZ) tablets are a unique form of treatment available for treating Chagas disease. Development of a liquid formulation containing BZ easy to…”
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Functional polylactide via ring-opening copolymerisation with allyl, benzyl and propargyl glycidyl ethers by Pound-Lana, Gwenaelle, Rabanel, Jean-Michel, Hildgen, Patrice, Mosqueira, Vanessa Carla Furtado

“…[Display omitted] •d,l-Lactide was copolymerised with allyl, benzyl and propargyl glycidyl ethers.•The glycidyl ether content in the polymer increased with…”
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Therapeutical approaches under investigation for treatment of Chagas disease by Bahia, Maria Terezinha, Diniz, Lívia de Figueiredo, Mosqueira, Vanessa Carla Furtado

“…A century after its discovery, American trypanosomiasis or Chagas disease remains a serious health problem in Latin America, where it affects around 7 - 8…”
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Release, transfer and partition of fluorescent dyes from polymeric nanocarriers to serum proteins monitored by asymmetric flow field-flow fractionation by de Oliveira, Maria Alice, Pound-Lana, Gwenaelle, Capelari-Oliveira, Patricia, Pontífice, Thaís Godinho, Silva, Sabrina Emanuelle Dias, Machado, Marina Guimarães Carvalho, Postacchini, Bruna Bueno, Mosqueira, Vanessa Carla Furtado

“…•The AF4 technique is an important tool to study the release, transfer, and partition of fluorescent dyes from polymeric nanoparticles.•Physically encapsulated…”
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Lychnopholide in Poly(d,l-Lactide)- Block -Polyethylene Glycol Nanocapsules Cures Infection with a Drug-Resistant Trypanosoma cruzi Strain at Acute and Chronic Phases by Branquinho, Renata Tupinambá, de Mello, Carlos Geraldo Campos, Oliveira, Maykon Tavares, Reis, Levi Eduardo Soares, Vieira, Paula Mello de Abreu, Saúde-Guimarães, Dênia Antunes, Mosqueira, Vanessa Carla Furtado, de Lana, Marta

“…Chagas disease remains neglected, and current chemotherapeutics present severe limitations. Lychnopholide (LYC) at low doses loaded in polymeric…”
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Mechanisms of interaction of biodegradable polyester nanocapsules with non-phagocytic cells by Trindade, Izabel Cristina, Pound-Lana, Gwenaelle, Pereira, Douglas Gualberto Sales, de Oliveira, Laser Antônio Machado, Andrade, Margareth Spangler, Vilela, José Mário Carneiro, Postacchini, Bruna Bueno, Mosqueira, Vanessa Carla Furtado

“…The interaction of polymer nanocapsules (NC) prepared from four biodegradable polyesters with variable polymer hydrophobicity (PCL, PLA, PLGA and PLA-PEG) was…”
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Higher oral efficacy of ravuconazole in self-nanoemulsifying systems in shorter treatment in experimental chagas disease by Spósito, Pollyanna Álvaro, Mazzeti, Ana Lia, de Castro, Kelly Christyne Miranda Pereira, Mendes, Priscila Fagundes, Urbina, Julio A., Bahia, Maria Terezinha, Mosqueira, Vanessa Carla Furtado

“…We investigated the in vitro activity and selectivity, and in vivo efficacy of ravuconazole (RAV) in self-nanoemulsifying delivery system (SNEDDS) against…”
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IR780-polymer conjugates for stable near-infrared labeling of biodegradable polyester-based nanocarriers by de Oliveira, Maria Alice, Guimarães Carvalho Machado, Marina, Dias Silva, Sabrina Emanuelle, Leite Nascimento, Thais, Martins Lima, Eliana, Pound-Lana, Gwenaelle, Mosqueira, Vanessa Carla Furtado

“…[Display omitted] •The NIR probe IR780 was derivatized and covalently linked to polylactide.•The polymer-dye conjugate provides stable fluorescence labelling…”
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Efficacy of Lychnopholide Polymeric Nanocapsules after Oral and Intravenous Administration in Murine Experimental Chagas Disease by de Mello, Carlos Geraldo Campos, Branquinho, Renata Tupinambá, Oliveira, Maykon Tavares, Milagre, Matheus Marques, Saúde-Guimarães, Dênia Antunes, Mosqueira, Vanessa Carla Furtado, Lana, Marta de

“…The etiological treatment of Chagas disease remains neglected. The compounds available show several limitations, mainly during the chronic phase. Lychnopholide…”
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Physical and biological effects of paclitaxel encapsulation on disteraroylphosphatidylethanolamine-polyethyleneglycol polymeric micelles by Oda, Caroline Mari Ramos, Malfatti-Gasperini, Antônio Augusto, Malachias, Angelo, Pound-Lana, Gwenaelle, Mosqueira, Vanessa Carla Furtado, Fernandes, Renata Salgado, Oliveira, Mônica Cristina de, de Barros, André Luis Branco, Leite, Elaine Amaral

“…[Display omitted] •SAXS analysis showed that encapsulation of paclitaxel affected the micelle packing.•Core radius increased while shell radius shrank, without…”
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