Search Results - "Furr‐Stimming, Erin"

Safety and efficacy of valbenazine for the treatment of chorea associated with Huntington's disease (KINECT-HD): a phase 3, randomised, double-blind, placebo-controlled trial by Furr Stimming, Erin, Claassen, Daniel O, Kayson, Elise, Goldstein, Jody, Mehanna, Raja, Zhang, Hui, Liang, Grace S, Haubenberger, Dietrich, Adams, Jamie, Beck, Christopher, Chen, Cheryl, Nance, Martha, Testa, Claudia, Huffman, Patricia, Chesire, Amy, Marshall, Frederick, Dayalu, Praveen, Stovall, Angela, Hall, Deborah, Hawkins, Jacob, Ginsburg, Letty, Moore, Henry, Mestre, Tiago, Thompson, Tanya, Connors, Natalie, Rosas, H. Diana, Daley, Allison, Kostyk, Sandra K., Mitchell, Casey, Hellman, Amy, Houston, Sheryl, Buchanan, Danielle, McDonell, Katherine, Factor, Stewart A., Sperin, Elaine, Hurt, Andrea, Wojcieszek, Joanne, Adurogbangba, Mike, Raymond, Lynn A., Corey-Bloom, Jody, Snell, Chase, Blair, Courtney, Sung, Victor, Antonioli, Sophia, Fung, Jacqueline, Laganiere, Simon, Sierra, Luis, Mallonee, William M., Suter, Greg, Bega, Danny, Brown, Zsa Zsa, Elmer, Lawrence, Vollmar, Nancy, del Castillo, Debra, Lin, Yi-Han, Andrzejewski, Kelly, Weigel, Patricia, Hawkins, Trevor, Kirby, Kendra, Retzik-Stahr, Cimmaron, Seeberger, Lauren, Dhall, Rohit, Rassmann, Anja, Luxmore, McKenzie, Scott, Burton, Bulica, Bisena, Boyd, James, Chan, Katherine, McFarland, Nikolaus, Rizer, Kyle, Conlon, Patricia, Suski, Valerie, Rodriguez-Porcel, Federico, Wilson, Sandra, Farrell, Christine, Hunter, David, Houghton, David, Seoane, Sarah, Gibbons, Clare, Rizek, Philippe, Kuprewicz, Robin, Lo, Steven, Cuturic, Miroslav, Segro, Vicki, Greenly, Kate, Revilla, Fredy, Urrea-Mendoza, Enrique, Black, Kevin J., Davis, Thomas, Stover, Natividad, Duker, Andrew, Van Gerpen, Jay, Hedera, Peter, Ondo, William, Anderson, Karen, Bradley, Stephen, Cheung, Ken, Frank, Samuel

“…Valbenazine is a highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor approved for treatment of tardive dyskinesia. To address the ongoing need…”
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Gene Expression Profiling in Huntington's Disease: Does Comorbidity with Depressive Symptoms Matter? by Colpo, Gabriela Delevati, Rocha, Natalia Pessoa, Furr Stimming, Erin, Teixeira, Antonio Lucio

“…Huntington's disease (HD) is an inherited neurodegenerative disease. Besides the well-characterized motor symptoms, HD is marked by cognitive impairment and…”
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A MDS evidence‐based review on treatments for Huntington's Disease by Ferreira, Joaquim J, Rodrigues, Filipe Brogueira, Duarte, Gonçalo, Mestre, Tiago, Bachoud‐Levi, Anne‐Catherine, Bentivoglio, Anna Rita, Burgunder, Jean‐Marc, Cardoso, Francisco, Claassen, Daniel O., Landwehrmeyer, G. Bernard, Kulisevsky, Jaime, Nirenberg, Melissa J., Rosser, Anne, Roth, Jan, Seppi, Klaus, Slawek, Jaroslaw, Furr‐Stimming, Erin, Tabrizi, Sarah J., Walker, Francis O., Vandenberghe, Wim, Costa, João, Sampaio, Cristina

“…© 2021 International Parkinson and Movement Disorder Society Background: Huntington's disease (HD) is a rare neurodegenerative disorder with protean clinical…”
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Sphingosine kinase 2 regulates protein ubiquitination networks in neurons by Diaz Escarcega, Rocio, Murambadoro, Karen, Valencia, Ricardo, Moruno-Manchon, Jose Felix, Furr Stimming, Erin E., Jung, Sung Yun, Tsvetkov, Andrey S.

“…Two sphingosine kinase isoforms, sphingosine kinase 1 (SPHK1) and sphingosine kinase 2 (SPHK2), synthesize the lipid sphingosine-1-phosphate (S1P) by…”
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Microglia Activation in Basal Ganglia Is a Late Event in Huntington Disease Pathophysiology by Rocha, Natalia P., Charron, Odelin, Latham, Leigh B., Colpo, Gabriela D., Zanotti-Fregonara, Paolo, Yu, Meixiang, Freeman, Leorah, Furr Stimming, Erin, Teixeira, Antonio L.

“…To define the role played by microglia in different stages of Huntington disease (HD), we used the TSPO radioligand [11C]-ER176 and PET to evaluate microglial…”
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The Black and African American Connections to Parkinson's Disease (BLAAC PD) study protocol by Chahine, Lana M, Louie, Naomi, Solle, J, Akçimen, Fulya, Ameri, Andrew, Augenbraun, Samantha, Avripas, Sabrina, Breaux, Sarah, Causey, Christopher, Chandra, Shivika, Dean, Marissa, Disbrow, Elizabeth A, Fanty, Lauren, Fernandez, Jessica, Foster, Erin R, Furr Stimming, Erin, Hall, Deborah, Hinson, Vanessa, Johnson-Turbes, Ashani, Jonas, Cabell, Kilbane, Camilla, Norris, Scott A, Nguyen, Bao-Tran, Padmanaban, Mahesh, Paquette, Kimberly, Parry, Carly, Pessoa Rocha, Natalia, Rawls, Ashley, Shamim, Ejaz A, Shulman, Lisa M, Sipma, Rebeka, Staisch, Julia, Traurig, Rami, von Coelln, Rainer, Wild Crea, Peter, Xie, Tao, Fang, Zih-Hua, O'Grady, Alyssa, Kopil, Catherine M, McGuire Kuhl, Maggie, Singleton, Andrew, Blauwendraat, Cornelis, Bandres-Ciga, Sara

“…Determining the genetic contributions to Parkinson's disease (PD) across diverse ancestries is a high priority as this work can guide therapeutic development…”
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Cytoplasmic sphingosine-1-phosphate pathway modulates neuronal autophagy by Moruno Manchon, Jose Felix, Uzor, Ndidi-Ese, Dabaghian, Yuri, Furr-Stimming, Erin E., Finkbeiner, Steven, Tsvetkov, Andrey S.

“…Autophagy is an important homeostatic mechanism that eliminates long-lived proteins, protein aggregates and damaged organelles. Its dysregulation is involved…”
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The Clinical Picture of Psychosis in Manifest Huntington's Disease: A Comprehensive Analysis of the Enroll-HD Database by Rocha, Natalia P, Mwangi, Benson, Gutierrez Candano, Carlos A, Sampaio, Cristina, Furr Stimming, Erin, Teixeira, Antonio L

“…Psychotic symptoms have been under-investigated in Huntington's disease (HD) and research is needed in order to elucidate the characteristics linked to the…”
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Educating Residents and Students in the Clinic by Furr Stimming, Erin, Soni, Madhu

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Stem cells in animal models of Huntington disease: A systematic review by Colpo, Gabriela Delevati, Furr Stimming, Erin, Teixeira, Antonio Lucio

“…Huntington's disease (HD) is an autosomal-dominant neurodegenerative disorder encoding a mutant form of the huntingtin protein (HTT). HD is pathologically…”
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Obsessive-compulsive and perseverative behaviors in Huntington's disease by Zadegan, Shayan Abdollah, Kupcha, Luke, Patino, Jorge, Rocha, Natalia Pessoa, Teixeira, Antonio L, Furr Stimming, Erin

“…Obsessive-compulsive and perseverative behaviors (OCBs/PBs) are characteristic features of Huntington's Disease (HD). Although a few recent research have…”
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Poster 288 Procedure Oriented Torsional Anatomy of the Proximal Arm for Spasticity Injection by Chiou-Tan, Faye, MD, Cianca, John C., MD, Pandit, Sindhu, MD,MBA, John, Joslyn, MD, Furr-Stimming, Erin, MD, Taber, Katherine H., PhD

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Inhibiting sphingosine kinase 2 mitigates mutant Huntingtin-induced neurodegeneration in neuron models of Huntington disease by Moruno-Manchon, Jose F, Uzor, Ndidi-Ese, Blasco-Conesa, Maria P, Mannuru, Sishira, Putluri, Nagireddy, Furr-Stimming, Erin E, Tsvetkov, Andrey S

“…Huntington disease (HD) is the most common inherited neurodegenerative disorder. It has no cure. The protein huntingtin causes HD, and mutations to it confer…”
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Neuroimmunology of Huntington’s Disease: Revisiting Evidence from Human Studies by Teixeira, Antonio Lucio, Furr-Stimming, Erin, Ribeiro, Fabiola M., Rocha, Natália Pessoa

“…Huntington’s disease (HD) is a neurodegenerative disorder characterized by selective loss of neurons in the striatum and cortex, which leads to progressive…”
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J05 Interim results from cohort 1 of the double-blind, dose-escalation phase I/II clinical trial of amt-130 (HD-genetrx-1) for early-stage huntington’s disease (HD) by Furr Stimming, Erin, Sung, Victor, Testa, Claudia, Kostyk, Sandra, Ross, Christopher A, Samii, Ali, Geschwind, Michael D, Hall, Deborah, Dayalu, Praveen, Lonser, Russell, Elder, Brad, Larson, Paul S, Cooper, David L, Clarkin, Marcie, Ali, Talaha M, Dolmetsch, Ricardo E

“…BackgroundHuntingtin (HTT) lowering therapies hold great promise to slow or halt neurodegeneration in Huntington’s disease (HD). AMT-130 is an investigational…”
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Altered nigrostriatal and nigrocortical functional connectivity in rapid eye movement sleep behavior disorder by Ellmore, Timothy M, Castriotta, Richard J, Hendley, Katie L, Aalbers, Brian M, Furr-Stimming, Erin, Hood, Ashley J, Suescun, Jessika, Beurlot, Michelle R, Hendley, Roy T, Schiess, Mya C

“…Rapid eye movement sleep behavior disorder (RBD) is a condition closely associated with Parkinson disease (PD). RBD is a sleep disturbance that frequently…”
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Sex Differences in Huntington's Disease: Evaluating the Enroll‐HD Database by Hentosh, Samantha, Zhu, Liang, Patino, Jorge, Furr, J. Weldon, Rocha, Natalia P., Furr Stimming, Erin

“…ABSTRACT Background Identifying sex‐related differences is critical for enhancing our understanding of factors that may impact prognosis and advance treatments…”
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An Exploratory Pilot Study of Neuropsychological Performance in Two Huntington Disease Centers of Excellence Clinics by Rossetti, M Agustina, Anderson, Kendra M, Hay, Kaitlyn R, Del Bene, Victor A, Celka, Andrea S, Piccolino, Adam, Nelson Sheese, Amelia L, Huynh, Melissa, Zhu, Liang, Claassen, Daniel O, Furr Stimming, Erin, Considine, Ciaran M

“…Abstract Objectives To describe the characteristics of patients receiving a clinical referral for neuropsychological evaluation in two Huntington’s Disease…”
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HAP40 is a conserved central regulator of Huntingtin and a potential modulator of Huntington's disease pathogenesis by Xu, Shiyu, Li, Gang, Ye, Xin, Chen, Dongsheng, Chen, Zhihua, Xu, Zhen, Daniele, Moretti, Tambone, Sara, Ceccacci, Alessandra, Tomei, Licia, Ye, Lili, Yu, Yue, Solbach, Amanda, Farmer, Stephen M, Stimming, Erin Furr, McAllister, George, Marchionini, Deanna M, Zhang, Sheng

“…Perturbation of huntingtin (HTT)'s physiological function is one postulated pathogenic factor in Huntington's disease (HD). However, little is known how HTT is…”
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Poster 350 Procedure Oriented Sectional Anatomy of the Knee by Pandit, Sindhu, MD, MBA, Chiou-Tan, Faye, MD, Furr-Stimming, Erin, MD, Harrell, John, MD, Taber, Katherine H., PhD, Zhang, Han, MD

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