Search Results - "Furlong, Terry"
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Posttransplantation cyclophosphamide for prevention of graft-versus-host disease after HLA-matched mobilized blood cell transplantation
Published in Blood (17-03-2016)“…The cumulative incidence of National Institutes of Health (NIH)-defined chronic graft-versus-host disease (GVHD) requiring systemic treatment is ∼35% at 1 year…”
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Multi-institutional study of post-transplantation cyclophosphamide as single-agent graft-versus-host disease prophylaxis after allogeneic bone marrow transplantation using myeloablative busulfan and fludarabine conditioning
Published in Journal of clinical oncology (01-11-2014)“…The clinical safety and efficacy of intravenous busulfan and fludarabine (IV Bu/Flu) myeloablative conditioning as well as graft-versus-host disease (GVHD)…”
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Pilot study of lithium to restore intestinal barrier function in severe graft-versus-host disease
Published in PloS one (17-08-2017)“…Severe intestinal graft-vs-host disease (GVHD) after allogeneic hematopoietic cell transplantation (HCT) causes mucosal ulceration and induces innate and…”
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Evaluation of Oral Beclomethasone Dipropionate for Prevention of Acute Graft-versus-Host Disease
Published in Biology of blood and marrow transplantation (01-06-2012)“…Results from two randomized trials have shown that oral beclomethasone dipropionate (BDP) is effective for treatment of acute gastrointestinal…”
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Low immunosuppressive burden after HLA-matched related or unrelated BMT using posttransplantation cyclophosphamide
Published in Blood (09-03-2017)“…The intensive and prolonged immunosuppressive therapy required to prevent or treat graft-versus-host disease (GVHD) after allogeneic blood or marrow…”
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Impact of Donor Statin Treatment on Graft-versus-Host Disease after Allogeneic Hematopoietic Cell Transplantation
Published in Transplantation and cellular therapy (01-11-2023)“…•Short-term donor statin treatment was ineffective in preventing severe acute graft-versus-host disease (GVHD).•Longer-term statin use in donors was…”
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Initial therapy of acute graft-versus-host disease with low-dose prednisone does not compromise patient outcomes
Published in Blood (26-03-2009)“…We hypothesized that initial treatment of acute graft-versus-host disease (GVHD) with low-dose glucocorticoids (prednisone-equivalent dose of 1 mg/kg per day)…”
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Alpha 1 Anti-Trypsin (AAT) Offers Potent Therapy for Steroid Resistant Gut Gvhd: Interim Results of a Phase I/II Clinical Study
Published in Blood (06-12-2014)“…Background: Graft-versus-host disease (GVHD) is a major complication of allogeneic hematopoietic cell transplantation (HCT). Severe acute GVHD of the…”
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Multi-institutional study of allogeneic bone marrow transplantation using myeloablative busulfan (Bu)/fludarabine (Flu) conditioning and short-course, single-agent graft-versus-host disease (GVHD) prophylaxis with high-dose, post-transplantation cyclophosphamide (PTCy)
Published in Journal of clinical oncology (20-05-2013)“…Abstract only 7006 Background: The clinical efficacy of 1) myeloablative BuFlu and 2) PTCy as GVHD prophylaxis have been independently shown in multiple…”
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Post-Transplantation Cyclophosphamide Following Busulfan and Fludarabine Myeloablative Conditioning Prevents Severe Acute and Chronic Graft-Versus-Host Disease and Minimizes Duration Of Immunosuppression: Results Of a Multi-Institutional Trial In Patients With High-Risk Hematologic Malignancies
Published in Blood (15-11-2013)“…Allogeneic blood or marrow transplantation (alloBMT) involves a multi-faceted platform with each component having significant implications for the overall…”
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Psoralen and ultraviolet A irradiation (PUVA) as therapy for steroid-resistant cutaneous acute graft-versus-host disease
Published in Biology of blood and marrow transplantation (01-01-2002)“…Psoralen plus ultraviolet A irradiation (PUVA) has immunomodulatory effects and is used to treat a variety of immune-mediated dermatologic diseases. We…”
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A pilot pharmacologic biomarker study of busulfan and fludarabine in hematopoietic cell transplant recipients
Published in Cancer chemotherapy and pharmacology (01-01-2012)“…Purpose Sixteen patients diagnosed with various hematologic malignancies participated in a phase II study evaluating the addition of rabbit antithymocyte…”
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Sirolimus (rapamycin) for the treatment of steroid-refractory acute graft-versus-host disease
Published in Transplantation (27-12-2001)“…In a pilot trial we evaluated the toxicity and efficacy of sirolimus (rapamycin) as second-line therapy for the treatment of acute graft-versus-host disease…”
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Therapy with mycophenolate mofetil for refractory acute and chronic graft-versus-host disease
Published in Bone marrow transplantation (Basingstoke) (20-04-2009)“…We evaluated the pharmacokinetics and efficacy of oral mycophenolate mofetil (MMF) for treatment of refractory graft-versus-host disease (GVHD). In a…”
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FK506 in Combination With Methotrexate for the Prevention of Graft-Versus-Host Disease After Marrow Transplantation From Matched Unrelated Donors
Published in Blood (01-11-1996)“…The safety and potential efficacy of FK506 in combination with a short course of methotrexate (MTX) for the prevention of acute graft-versus-host disease…”
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Tacrolimus (FK506) Alone or in Combination With Methotrexate or Methylprednisolone for the Prevention of Acute Graft-Versus-Host Disease After Marrow Transplantation From HLA-Matched Siblings: A Single-Center Study
Published in Blood (15-06-1995)“…The pharmacokinetics, safety, and efficacy in marrow transplantation of FK506-based immunosuppression for graft-ver-sus-host disease (GVHD) prophylaxis was…”
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A Retrospective Comparison of Tacrolimus versus Cyclosporine with Methotrexate for Immunosuppression after Allogeneic Hematopoietic Cell Transplantation with Mobilized Blood Cells
Published in Biology of blood and marrow transplantation (01-07-2011)“…This retrospective study was performed to compare results with tacrolimus versus cyclosporine in combination with methotrexate for immunosuppression after…”
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A Phase I/II Study of Mycophenolate Mofetil in Combination with Cyclosporine for Prophylaxis of Acute Graft-versus-Host Disease after Myeloablative Conditioning and Allogeneic Hematopoietic Cell Transplantation
Published in Biology of blood and marrow transplantation (01-07-2005)“…In a phase I/II study, the combination of cyclosporine (CSP) and mycophenolate mofetil (MMF) was investigated as graft-versus-host disease (GVHD) prophylaxis…”
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