Search Results - "Furlan, Ricardo L E"

Chemically engineered essential oils prepared through thiocyanation under solvent-free conditions: chemical and bioactivity alteration by Lescano, Liz E., Salazar, Mario O., Furlan, Ricardo L. E.

“…The generation of chemically engineered essential oils (CEEOs) prepared from bi-heteroatomic reactions using ammonium thiocyanate as a source of bioactive…”
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A Tyrosinase Inhibitor from a Nitrogen-Enriched Chemically Engineered Extract by Solís, Carlos M, Salazar, Mario O, Ramallo, I. Ayelen, García, Paula, Furlan, Ricardo L. E

“…The enzyme tyrosinase is involved in the biosynthesis of melanin and the enzymatic browning of fruits and vegetables, and therefore, its inhibitors have…”
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A Bioactive Trypanosoma cruzi Bromodomain Inhibitor from Chemically Engineered Extracts by Ramallo, I. Ayelen, Alonso, Victoria L, Rua, Federico, Serra, Esteban, Furlan, Ricardo L. E

“…A set of chemically engineered extracts enriched in compounds including N–N and N–O fragments in their structures was prepared. Bromodomain binding screening…”
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Chemically Engineered Extracts: Source of Bioactive Compounds by Ramallo, I. Ayelen, Salazar, Mario O, Mendez, Luciana, Furlan, Ricardo L. E

“…Biological research and drug discovery critically depend on access to libraries of small molecules that have an affinity for biomacromolecules. By virtue of…”
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Thin layer chromatography assay to detect laccase inhibitors by Cabezudo, Ignacio, L. E. Furlan, Ricardo

“…[Display omitted] •Thin layer chromatography assay developed for laccase inhibitor detection.•Optimization of on-plate laccase reaction with substrate for…”
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Selection and Amplification of Hosts from Dynamic Combinatorial Libraries of Macrocyclic Disulfides by Otto, Sijbren, Ricardo L. E. Furlan, Jeremy K. M. Sanders

“…We have discovered two receptors for two different guests from a single dynamic combinatorial library. Each of the two guests amplifies the formation of a…”
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A New Fluorinated Tyrosinase Inhibitor from a Chemically Engineered Essential Oil by García, Paula, Salazar, Mario O, Ramallo, I. Ayelen, Furlan, Ricardo L. E

“…The generation of fluorinated essential oils as a source of bioactive compounds is described. Most of the components of the natural mixtures were altered,…”
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reversed‐phase compatible thin‐layer chromatography autography for the detection of acetylcholinesterase inhibitors by Ramallo, I. Ayelen, García, Paula, Furlan, Ricardo L. E

“…A dual readout autographic assay to detect acetylcholinesterase inhibitors present in complex matrices adsorbed on reversed‐phase or normal‐phase thin‐layer…”
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Chemically engineered extracts as an alternative source of bioactive natural product-like compounds by López, Silvia N, Ramallo, I. Ayelen, Sierra, Manuel Gonzalez, Zacchino, Susana A, Furlan, Ricardo L.E

“…The access to libraries of molecules with interesting biomolecular properties is a limiting step in the drug discovery process. By virtue of a long molecular…”
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Brominated Extracts As Source of Bioactive Compounds by Méndez, Luciana, Salazar, Mario O, Ramallo, I. Ayelen, Furlan, Ricardo L. E

“…The chemical composition and the biomolecular properties of a crude plant extract were altered through bromination leading to the discovery of an…”
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Engineering multilayer chemical networks by Martinez-Amezaga, Maitena, Orrillo, A. Gastón, Furlan, Ricardo L. E

“…Dynamic multilevel systems emerged in the last few years as new platforms to study thermodynamic systems. In this work, unprecedented fully communicated…”
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1,3,4-oxadiazoles as inhibitors of the atypical member of the BET family bromodomain factor 3 from Trypanosoma cruzi ( Tc BDF3) by Alonso, Victoria L, Escalante, Andrea M, Rodríguez Araya, Elvio, Frattini, Gianfranco, Tavernelli, Luis E, Moreno, Diego M, Furlan, Ricardo L E, Serra, Esteban

“…Chagas disease, caused by the protozoan parasite , affects millions globally, with increasing urban cases outside of Latin America. Treatment is based on two…”
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Host Amplification in a Dithioacetal-Based Dynamic Covalent Library by Orrillo, A. Gastón, Escalante, Andrea. M, Furlan, Ricardo L. E

“…Molecular amplification in a dithioacetal-based dynamic library is described for the first time. The homatropine induced selection, amplification, and…”
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Dithioacetal Exchange: A New Reversible Reaction for Dynamic Combinatorial Chemistry by Orrillo, A. Gastón, Escalante, Andrea M., Furlan, Ricardo L. E.

“…Reversibility of dithioacetal bond formation is reported under acidic mild conditions. Its utility for dynamic combinatorial chemistry was explored by…”
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Multiresponse Optimisation Applied to the Development of a TLC Autography for the Detection of Tyrosinase Inhibitors by García, Paula, Furlan, Ricardo L. E

“…INTRODUCTION: Autographic methods are useful tools to detect bioactive compounds in complex matrixes. Experimental design and optimisation techniques were…”
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Chemically engineered extracts: Bioactivity alteration through sulfonylation by Salazar, Mario O., Ramallo, I. Ayelen, Micheloni, Oscar, Sierra, Manuel Gonzalez, Furlan, Ricardo L.E.

“…The chemical composition and the biomolecular properties of a series of crude plant extracts were altered without previous knowledge of their detailed chemical…”
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Discovery of β-glucosidase inhibitors from a chemically engineered extract prepared through ethanolysis by Ramallo, I Ayelen, Sierra, Manuel González, Furlan, Ricardo L E

“…A series of vegetal extracts have been chemically altered by ethanolysis. The effect of the reaction on the inhibition of the enzyme β-glucosidase properties…”
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Antifungal Activity and Studies on Mode of Action of Novel Xanthoxyline-Derived Chalcones by Boeck, Paula, Leal, Paulo C., Yunes, Rosendo A., Filho, Valdir Cechinel, López, Silvia, Sortino, Maximiliano, Escalante, Andrea, Furlán, Ricardo L. E., Zacchino, Susana

“…Chalcones and chalcone‐like compounds, most of them new ones, prepared by base‐catalyzed condensation of appropriate aldehydes and xanthoxyline, were tested…”
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Discovery of a Biologically Active Bromodomain Inhibitor by Target-Directed Dynamic Combinatorial Chemistry by García, Paula, Alonso, Victoria L, Serra, Esteban, Escalante, Andrea M, Furlan, Ricardo L. E

“…Target-directed dynamic combinatorial chemistry (DCC) has emerged as a strategy for the identification of inhibitors of relevant therapeutic targets. In this…”
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Unsaturated Long Chain Free Fatty Acids Are Input Signals of the Salmonella enterica PhoP/PhoQ Regulatory System by Viarengo, Gastón, Sciara, Mariela I., Salazar, Mario O., Kieffer, Pablo M., Furlán, Ricardo L.E., García Véscovi, Eleonora

“…The Salmonella enterica serovar Typhimurium PhoP/PhoQ system has largely been studied as a paradigmatic two-component regulatory system not only to dissect…”
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