Search Results - "Fure, Hilde"
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1
Effect of the anticoagulant, storage time and temperature of blood samples on the concentrations of 27 multiplex assayed cytokines – Consequences for defining reference values in healthy humans
Published in Cytokine (Philadelphia, Pa.) (01-09-2017)“…•The cytokine levels are lower in plasma than in serum.•Cytokines should be analysed in immediately cooled EDTA or citrated blood samples.•Only EDTA blood…”
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2
Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model
Published in PloS one (27-06-2019)“…Right ventricular (RV) myocardial dysfunction is a common feature in septic shock. It can worsen outcome, but the etiology is poorly understood. Pulmonary…”
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3
Venous Air Embolism Activates Complement C3 Without Corresponding C5 Activation and Trigger Thromboinflammation in Pigs
Published in Frontiers in immunology (15-03-2022)“…Air embolism may complicate invasive medical procedures. Bubbles trigger complement C3-mediated cytokine release, coagulation, and platelet activation in human…”
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4
A Novel Porcine Model of Ischemia-Reperfusion Injury After Cross-Clamping the Thoracic Aorta Revealed Substantial Cardiopulmonary, Thromboinflammatory and Biochemical Changes Without Effect of C1-Inhibitor Treatment
Published in Frontiers in immunology (01-04-2022)“…Ischemic injury worsens upon return of blood and innate immunity including the complement system play a central role in ischemia-reperfusion injury (IRI) as in…”
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5
Systemic CD14 Inhibition Attenuates Organ Inflammation in Porcine Escherichia coli Sepsis
Published in Infection and Immunity (01-09-2013)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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6
CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray
Published in PloS one (23-02-2015)“…Systemic inflammation like in sepsis is still lacking specific diagnostic markers and effective therapeutics. The first line of defense against intruding…”
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7
Dental and Periodontal Health in Acute Intermittent Porphyria
Published in Life (Basel, Switzerland) (19-08-2022)“…In the inherited metabolic disorder acute intermittent porphyria (AIP), high sugar intake prevents porphyric attacks due to the glucose effect and the…”
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8
NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies
Published in mAbs (01-01-2020)“…The mechanism of action of recombinant IgG2/4 antibodies involves blocking of their target without the induction of effector functions. Examples are eculizumab…”
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9
Blood Transcriptome Analysis of Septic Patients Reveals a Long Non-Coding Alu -RNA in the Complement C5a Receptor 1 Gene
Published in Non-coding RNA (29-03-2022)“…Many severe inflammation conditions are complement-dependent with the complement component C5a-C5aR1 axis as an important driver. At the RNA level, the blood…”
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10
The role of complement C3 opsonization, C5a receptor, and CD14 in E. coli-induced up-regulation of granulocyte and monocyte CD11b/CD18 (CR3), phagocytosis, and oxidative burst in human whole blood
Published in Journal of leukocyte biology (01-06-2007)“…The relative role of complement and CD14 in Escherichia coli‐induced leukocyte CD11b up‐regulation, phagocytosis, and oxidative burst in human whole blood was…”
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11
Combined inhibition of complement and CD14 abolish E. coli-induced cytokine-, chemokine- and growth factor-synthesis in human whole blood
Published in Molecular immunology (01-08-2008)“…The relative role of complement and CD14 in E. coli-induced cytokine synthesis in an in vitro human whole blood model of sepsis was examined. Fresh…”
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12
Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response
Published in Genomics data (01-09-2015)“…Non-sterile pathogen-induced sepsis and sterile inflammation like in trauma or ischemia–reperfusion injury may both coincide with the life threatening systemic…”
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13
Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood
Published in The Journal of immunology (1950) (01-12-2021)“…Abstract Venous air embolism, which may complicate medical and surgical procedures, activates complement and triggers thromboinflammation. In…”
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14
A Conformational Change of Complement C5 Is Required for Thrombin-Mediated Cleavage, Revealed by a Novel Ex Vivo Human Whole Blood Model Preserving Full Thrombin Activity
Published in The Journal of immunology (1950) (15-09-2021)“…Thrombin activation of C5 connects thrombosis to inflammation. Complement research in whole blood ex vivo necessitates anticoagulation, which potentially…”
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15
Intestinal inflammatory profile shows increase in a diversity of biomarkers in irritable bowel syndrome
Published in Scandinavian journal of gastroenterology (03-05-2020)“…Background: It has been proposed that irritable bowel syndrome (IBS) is a low-grade mucosal inflammatory disease. Objective: To characterize the intestinal…”
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16
A conformational change of complement C5 is required for thrombin-mediated cleavage, revealed by a novel ex vivo human whole blood model preserving full thrombin activity
Published in The Journal of immunology (1950) (2021)“…Thrombin activation of C5 connects thrombosis to inflammation. Complement research in whole blood ex vivo necessitates anticoagulation, which potentially…”
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17
Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood
Published in The Journal of immunology (1950) (2021)“…Venous air embolism, which may complicate medical and surgical procedures, activates complement and triggers thromboinflammation. In lepirudin-anticoagulated…”
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Journal Article -
18
Venous Air Embolism Activates Complement C3 Without Corresponding C5 Activation and Trigger Thromboinflammation in Pigs
Published in Frontiers in immunology (2022)“…Introduction Air embolism may complicate invasive medical procedures. Bubbles trigger complement C3-mediated cytokine release, coagulation, and platelet…”
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19
A complement-dependent human long-noncoding RNA induced by Staphylococcus aureus
Published in Molecular immunology (01-09-2017)Get full text
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20
Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII
Published in Acta biomaterialia (01-08-2017)“…[Display omitted] Alginate microspheres are presently under evaluation for future cell-based therapy. Their ability to induce harmful host reactions needs to…”
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