Search Results - "Fur, G L"

SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor by Rinaldi-Carmona, M, Barth, F, Millan, J, Derocq, J M, Casellas, P, Congy, C, Oustric, D, Sarran, M, Bouaboula, M, Calandra, B, Portier, M, Shire, D, Brelière, J C, Le Fur, G L

“…Based on both binding and functional data, this study introduces SR 144528 as the first, highly potent, selective and orally active antagonist for the CB2…”
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Modulation and functional involvement of CB2 peripheral cannabinoid receptors during B-cell differentiation by CARAYON, P, MARCHAND, J, LE FUR, G, DEFRANCE, T, CASELLAS, P, DUSSOSSOY, D, DEROCQ, J.-M, JBILO, O, BORD, A, BOUABOULA, M, GALIEGUE, S, MONDIERE, P, PENARIER, G

“…Two subtypes of G-protein-coupled cannabinoid receptors have been identified to date: the CB1 central receptor subtype, which is mainly expressed in the brain,…”
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Cloning and characterization of PRAX-1. A new protein that specifically interacts with the peripheral benzodiazepine receptor by Galiègue, S, Jbilo, O, Combes, T, Bribes, E, Carayon, P, Le Fur, G, Casellas, P

“…Using a cytoplasmic domain of the peripheral benzodiazepine receptor (PBR) as a bait in the yeast two-hybrid system, we have isolated a cDNA encoding a new…”
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Blockade of cannabinoid CB1 receptors improves renal function, metabolic profile, and increased survival of obese Zucker rats by Janiak, P., Poirier, B., Bidouard, J.-P., Cadrouvele, C., Pierre, F., Gouraud, L., Barbosa, I., Dedio, J., Maffrand, J.-P., Le Fur, G., O'Connor, S., Herbert, J.-M.

“…Obesity is a major risk factor in the development of chronic renal failure. Rimonabant, a cannabinoid CB1 receptor antagonist, improves body weight and…”
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Blockade of CRF1 or V1b receptors reverses stress-induced suppression of neurogenesis in a mouse model of depression by ALONSO, R, GRIEBEL, G, PAVONE, G, STEMMELIN, J, LE FUR, G, SOUBRIE, P

“…Repeated exposure to stress is known to induce structural remodelling and reduction of neurogenesis in the dentate gyrus. Corticotrophin-releasing factor (CRF)…”
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Sub-Band Time Reversal Efficiency Measurement: An Enhanced Method for Efficiency Characterization of UWB Antennas by Naqvi, I. H., Le Fur, G., Sol, J., Besnier, P., Sharaiha, A.

“…Antenna efficiency is a critical parameter if one wishes to characterize the performance of an antenna. It is a measure of the radiation quality of an antenna…”
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Improvement of memory in rodents by the selective CB1 cannabinoid receptor antagonist, SR 141716 by TERRANOVA, J.-P, STORME, J.-J, LAFON, N, PERIO, A, RINALDI-CARMONA, M, LE FUR, G, SOUBRIE, P

“…Social short-term memory in rodents is based on the recognition of a juvenile by an adult conspecific when the juvenile is presented on two successive…”
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Involvement of Peripheral Benzodiazepine Receptors in the Protection of Hematopoietic Cells Against Oxygen Radical Damage by Carayon, P., Portier, M., Dussossoy, D., Bord, A., Petitprêtre, G., Canat, X., Fur, G.Le, Casellas, P.

“…Several putative functions have been attributed to the peripheral benzodiazepine receptor (PBR), but its precise physiologic role has not been elucidated. In…”
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Blockade of cannabinoid receptors by SR141716 selectively increases fos expression in rat mesocorticolimbic areas via reduced dopamine D sub(2) function by Alonso, R, Voutsinos, B, Fournier, M, Labie, C, Steinberg, R, Souilhac, J, Fur, G L, Soubrie, P

“…The present study investigated, in rats, whether blockade of cannabinoid CB sub(1) receptors may alter Fos protein expression in a manner comparable to that…”
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In vitro and in vivo biological activities of SR140333, a novel potent non-peptide tachykinin NK1 receptor antagonist by Emonds-Alt, X, Doutremepuich, J D, Heaulme, M, Neliat, G, Santucci, V, Steinberg, R, Vilain, P, Bichon, D, Ducoux, J P, Proietto, V

“…(S)1-(2-[3-(3,4-dichlorophenyl)-1-(3-isopropoxyphenylacetyl)pip eridin-3- yl]ethyl)-4-phenyl-1-azoniabicyclo[2.2.2]octane chloride (SR140333) is a new…”
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Primary structure and functional expression of mouse pituitary and human brain corticotrophin releasing factor receptors by Vita, Natalio, Laurent, Patrick, Lefort, Sylvie, Chalon, Pascale, Lelias, Jean-Michel, Kaghad, Mourad, Le Fur, Gérard, Caput, Daniel, Ferrara, Pascual

“…Corticotrophin-releasing factor (CRF) is the principal hypothalamic factor governing the pituitary-adrenal axis, but the wide extra-pituitary distribution of…”
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Blockade of cannabinoid receptors by SR141716 selectively increases fos expression in rat mesocorticolimbic areas via reduced dopamine D2 function by ALONSO, R, VOUTSINOS, B, FOURNIER, M, LABIE, C, STEINBERG, R, SOUILHAC, J, LE FUR, G, SOUBRIE, P

“…The present study investigated, in rats, whether blockade of cannabinoid CB1 receptors may alter Fos protein expression in a manner comparable to that observed…”
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Biochemical and Pharmacological Profile of a Potent and Selective Nonpeptide Antagonist of the Neurotensin Receptor by Gully, Danielle, Canton, Maryse, Boigegrain, Robert, Jeanjean, Francis, Molimard, Jean-Charles, Poncelet, Martine, Gueudet, Christiane, Heaulme, Michel, Leyris, Roger, Brouard, Aline, Pelaprat, Didier, Labbe-Jullie, Catherine, Mazella, Jean, Soubrie, Philippe, Maffrand, Jean-Pierre, Rostene, William, Kitabgi, Patrick, Le Fur, Gerard

“…We describe the characteristics of SR 48692, a selective, nonpeptide antagonist of the neurotensin receptor. In vitro, this compound competitively…”
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In vitro functional evidence of different neurotensin‐receptors modulating the motor response of human colonic muscle strips by Croci, Tiziano, Aureggi, Giulio, Guagnini, Fabio, Manara, Luciano, Gully, Danielle, Le Fur, Gérard, Maffrand, Jean‐Pierre, Mukenge, Sylvain, Ferla, Gianfranco, Ferrara, Pascual, Chalon, Pascale, Vita, Natalio

“…The newly developed non‐peptide neurotensin (NT)‐receptor antagonists SR 48692 and SR 142948 were used to challenge NT responses of human colonic circular…”
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In vitro functional evidence of neuronal cannabinoid CB sub(1) receptors in human ileum by Croci, T, Manara, L, Aureggi, G, Guagnini, F, Rinaldi-Carmona, M, Maffrand, J-P, Fur, G L, Mukenge, S, Ferla, G

“…We investigated the effect of the cannabinoid agonist (+)WIN-55212-2 on human ileum longitudinal smooth muscle preparations, either electrically stimulated or…”
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Poster abstracts by Ferrie, J., Shipley, M., Cappuccio, F., Brunner, E., Miller, M., Kumari, M., Marmot, M., Coenen, A., Castillo, J. L., Araya, F., Bustamante, G., Montecino, L., Torres, C., Oporto, S., Gronli, J., Fiske, E., Murison, R., Bjorvatn, B., Sorensen, E., Ursin, R., Portas, C. M., Rajaraman, S., Gribok, A., Wesensten, N., Balkin, T., Reifman, J., Dursunoglu, N., Ozkurt, S., Baser, S., Delen, O., Sarikaya, S., Sadler, P., Mitchell, P., Françon, D., Decobert, M., Herve, B., Richard, A., Griebel, G., Avenet, P., Scatton, B., Fur, G. L., Eckert, D., Jordan, A., Wellman, A., Smith, S., Malhotra, A., White, D., Bruck, D., Thomas, I., Kritikos, A., Oertel, W., Stiasny-Kolster, K., Garcia-Borreguero, D., Poewe, W., Hoegl, B., Kohnen, R., Schollmayer, E., Keffel, J., Trenkwalder, C., Valle, A., Roizenblatt, S., Fregni, F., Boggio, P., Tufik, S., Ward, K., Robertson, L., Palmer, L., Eastwood, P., Hillman, D., Lee, J., Mukherjee, S., de Padova, V., Barbato, G., Ficca, G., Zilli, I., Salzarulo, P., Veldi, M., Hion, T., Vasar, V., Kull, M., Nowak, L., Davis, J., Latzer, Y., Tzischinsky, O., Crowley, S., Carskadon, M., Anca-Herschkovitsch, M., Frey, D., Ortega, J., Wiseman, C., Farley, C., Wright, K., Campbell, A., Neill, A., Spiegel, K., Leproult, R., Tasali, E., Scherberg, N., van Cauter, E., Noradina, A. T.

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Role of tachykinins in castor oil diarrhoea in rats by Croci, Tiziano, Landi, Marco, Emonds‐Alt, Xavier, Fur, Gérard, Maffrand, Jean‐Pierre, Manara, Luciano

“…We set out to ascertain the role of tachykinins, neurokinin A and substance P, in castor oil‐induced diarrhoea in rats as disclosed by the inhibitory effect of…”
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Functional identification of rat atypical β‐adrenoceptors by the first β3‐selective antagonists, aryloxypropanolaminotetralins by Manara, Luciano, Badone, Domenico, Baroni, Marco, Boccardi, Giovanni, Cecchi, Roberto, Croci, Tiziano, Giudice, Antonina, Guzzi, Umberto, Landi, Marco, Fur, Gérard

“…1 We have assessed the relative abilities of compounds belonging to the new aryloxypropanolaminotetralin (APAT) class and of the reference…”
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Cloning and expression of a complementary DNA encoding a high affinity human neurotensin receptor by Vita, N., Laurent, P., Lefort, S., Chalon, P., Dumont, X., Kaghad, M., Gully, D., Le Fur, G., Ferrara, P., Caput, D.

“…A human neurotensin receptor (hNTR) cDNA was cloned from the colonic adenocarcinoma cell line HT29. The cloned cDNA encodes a putative peptide of 418 amino…”
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Pharmacological characterization of SR 47436, a new nonpeptide AT1 subtype angiotensin II receptor antagonist by Cazaubon, C, Gougat, J, Bousquet, F, Guiraudou, P, Gayraud, R, Lacour, C, Roccon, A, Galindo, G, Barthelemy, G, Gautret, B

“…SR 47436, 2-n-butyl-3-[(2'-(1H-tetrazol-5-yl)-biphenyl-4-yl) methyl]-1,3-diaza-spiro[4,4]non-1-en-4-one, is a new potent and selective AT1 angiotensin II (AII)…”
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