Search Results - "Funnell, Jessica L."

Heterogeneity of murine periosteum progenitors involved in fracture healing by Matthews, Brya G, Novak, Sanja, Sbrana, Francesca V, Funnell, Jessica L, Cao, Ye, Buckels, Emma J, Grcevic, Danka, Kalajzic, Ivo

“…The periosteum is the major source of cells involved in fracture healing. We sought to characterize progenitor cells and their contribution to bone fracture…”
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Soft Elasticity-Associated Signaling and Bone Morphogenic Protein 2 Are Key Regulators of Mesenchymal Stem Cell Spheroidal Aggregates by Cesarz, Zoe, Funnell, Jessica L, Guan, Jianjun, Tamama, Kenichi

“…Cell therapy with adult mesenchymal stem cells (MSCs) is a promising approach to regenerative medicine and autoimmune diseases. There are various approaches to…”
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Magnetic Composite Biomaterials for Neural Regeneration by Funnell, Jessica L, Balouch, Bailey, Gilbert, Ryan J

“…Nervous system damage caused by physical trauma or degenerative diseases can result in loss of sensory and motor function for patients. Biomaterial…”
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Electrospun Fiber Scaffolds for Engineering Glial Cell Behavior to Promote Neural Regeneration by Puhl, Devan L, Funnell, Jessica L, Nelson, Derek W, Gottipati, Manoj K, Gilbert, Ryan J

“…Electrospinning is a fabrication technique used to produce nano- or micro- diameter fibers to generate biocompatible, biodegradable scaffolds for tissue…”
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Aligned Fingolimod-Releasing Electrospun Fibers Increase Dorsal Root Ganglia Neurite Extension and Decrease Schwann Cell Expression of Promyelinating Factors by Puhl, Devan L, Funnell, Jessica L, D'Amato, Anthony R, Bao, Jonathan, Zagorevski, Dmitri V, Pressman, Yelena, Morone, Daniel, Haggerty, Agnes E, Oudega, Martin, Gilbert, Ryan J

“…Researchers are investigating the use of biomaterials with aligned guidance cues, like those provided by aligned electrospun fibers, to facilitate axonal…”
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Poly(pro-curcumin) Materials Exhibit Dual Release Rates and Prolonged Antioxidant Activity as Thin Films and Self-Assembled Particles by Chen, Ruiwen, Funnell, Jessica L., Quinones, Geraldine B., Bentley, Marvin, Capadona, Jeffrey R., Gilbert, Ryan J., Palermo, Edmund F.

“…Curcumin is a natural polyphenol that exhibits remarkable antioxidant and anti-inflammatory activities; however, its clinical application is limited in part by…”
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Assessing the combination of magnetic field stimulation, iron oxide nanoparticles, and aligned electrospun fibers for promoting neurite outgrowth from dorsal root ganglia in vitro by Funnell, Jessica L., Ziemba, Alexis M., Nowak, James F., Awada, Hussein, Prokopiou, Nicos, Samuel, Johnson, Guari, Yannick, Nottelet, Benjamin, Gilbert, Ryan J.

“…Magnetic fiber composites combining superparamagnetic iron oxide nanoparticles (SPIONs) and electrospun fibers have shown promise in tissue engineering fields…”
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Electrospun fiber-mediated delivery of neurotrophin-3 mRNA for neural tissue engineering applications by Puhl, Devan L., Funnell, Jessica L., Fink, Tanner D., Swaminathan, Anuj, Oudega, Martin, Zha, R. Helen, Gilbert, Ryan J.

“…Aligned electrospun fibers provide topographical cues and local therapeutic delivery to facilitate robust peripheral nerve regeneration. mRNA delivery enables…”
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Multivariate analysis reveals topography dependent relationships amongst neurite morphological features from dorsal root ganglia neurons by Nelson, Derek W, Puhl, Devan L, Funnell, Jessica L, Kruger, Uwe, Gilbert, Ryan J

“…Nerve guidance scaffolds containing anisotropic architectures provide topographical cues to direct regenerating axons through an injury site to reconnect the…”
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Conventional immunomarkers stain a fraction of astrocytes in vitro: A comparison of rat cortical and spinal cord astrocytes in naïve and stimulated cultures by Balouch, Bailey, Funnell, Jessica L., Ziemba, Alexis M., Puhl, Devan L., Lin, Kathy, Gottipati, Manoj K., Gilbert, Ryan J.

“…Astrocytes are responsible for a wide variety of essential functions throughout the central nervous system. The protein markers glial fibrillary acidic protein…”
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Delivery of TGFβ3 from Magnetically Responsive Coaxial Fibers Reduces Spinal Cord Astrocyte Reactivity In Vitro by Funnell, Jessica L., Fougere, Jasper, Zahn, Diana, Dutz, Silvio, Gilbert, Ryan J.

“…A spinal cord injury (SCI) compresses the spinal cord, killing neurons and glia at the injury site and resulting in prolonged inflammation and scarring that…”
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One-Pot Assembly of Drug-Eluting Silk Coatings with Applications for Nerve Regeneration by Fink, Tanner D., Funnell, Jessica L., Gilbert, Ryan J., Zha, R. Helen

“…Clinical use of polymeric scaffolds for tissue engineering often suffers from their inability to promote strong cellular interactions. Functionalization with…”
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In Vitro Assessment of Protamine Toxicity with Neural Cells, Its Therapeutic Potential to Counter Chondroitin Sulfate Mediated Neuron Inhibition, and Its Effects on Reactive Astrocytes by Nelson, Derek W., Funnell, Jessica L., Cheung, Conrad H., Quinones, Geraldine B., Mendoza, Christina S., Bentley, Marvin, Gilbert, Ryan J.

“…Multiple therapies have been studied to ameliorate the neuroinhibitory cues present after traumatic injury to the central nervous system. Two previous in vitro…”
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Development of a Slow-Degrading Polymerized Curcumin Coating for Intracortical Microelectrodes by Ziemba, Alexis M., Woodson, Mary Clare Crochiere, Funnell, Jessica L., Wich, Douglas, Balouch, Bailey, Rende, Deniz, Amato, Dahlia N., Bao, Jonathan, Oprea, Ingrid, Cao, Dominica, Bajalo, Neda, Ereifej, Evon S., Capadona, Jeffrey R., Palermo, Edmund F., Gilbert, Ryan J.

“…Intracortical microelectrodes are used with brain–computer interfaces to restore lost limb function following nervous system injury. While promising, recording…”
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Delivery of TGFβ3 from Magnetically Responsive Coaxial Fibers Reduces Spinal Cord Astrocyte Reactivity In Vitro (Adv. Biology 10/2024) by Funnell, Jessica L., Fougere, Jasper, Zahn, Diana, Dutz, Silvio, Gilbert, Ryan J.

“…Drug Delivery Spinal cord injury (SCI) is a devastating condition that severely impacts patient quality of life, and there are no available treatments that…”
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Magnetic Electrospun Fibers for Neural Regeneration Applications by Funnell, Jessica L

“…Nervous system damage caused by physical trauma or degenerative diseases can result in loss of sensory and motor function for patients. Biomaterial…”
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