Search Results - "Funk, Jason A"

Persistent disruption of mitochondrial homeostasis after acute kidney injury by Funk, Jason A, Schnellmann, Rick G

“…While mitochondrial dysfunction is a pathological process that occurs after acute kidney injury (AKI), the state of mitochondrial homeostasis during the injury…”
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Formoterol Restores Mitochondrial and Renal Function after Ischemia-Reperfusion Injury by JESINKEY, Sean R, FUNK, Jason A, JAY STALLONS, L, WILLS, Lauren P, MEGYESI, Judit K, BEESON, Craig C, SCHNELLMANN, Rick G

“…Mitochondrial biogenesis may be an adaptive response necessary for meeting the increased metabolic and energy demands during organ recovery after acute injury,…”
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Metformin therapy in a transgenic mouse model of Huntington's disease by Ma, Thong C., Buescher, Jessica L., Oatis, Benjamin, Funk, Jason A., Nash, Andrew J., Carrier, Raeann L., Hoyt, Kari R.

“…Huntington's disease (HD) is a hereditary neurodegenerative disease that leads to striatal degeneration and a severe movement disorder. We used a transgenic…”
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Voluntary exercise protects hippocampal neurons from trimethyltin injury: Possible role of interleukin-6 to modulate tumor necrosis factor receptor-mediated neurotoxicity by Funk, Jason A, Gohlke, Julia, Kraft, Andrew D, McPherson, Christopher A, Collins, Jennifer B, Jean Harry, G

“…Highlight ► Voluntary exercise elevates hippocampal IL-6 offering protection against chemical-induced hippocampal injury associated with TNF receptor…”
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5-hydroxytryptamine receptor stimulation of mitochondrial biogenesis by Rasbach, Kyle A, Funk, Jason A, Jayavelu, Tamilselvan, Green, Peter T, Schnellmann, Rick G

“…Mitochondrial dysfunction is both a cause and target of reactive oxygen species during ischemia-reperfusion, drug, and toxicant injury. After injury, renal…”
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Characterization of Renal Toxicity in Mice Administered the Marine Biotoxin Domoic Acid by FUNK, Jason A, JANECH, Michael G, DILLON, Joshua C, BISSLER, John J, SIROKY, Brian J, DARWIN BELL, P

“…Domoic acid (DA), an excitatory amino acid produced by diatoms belonging to the genus Pseudo-nitzschia, is a glutamate analog responsible for the neurologic…”
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Tumor necrosis factor p55 and p75 receptors are involved in chemical-induced apoptosis of dentate granule neurons by Harry, G. Jean, Lefebvre d'Hellencourt, Christian, McPherson, Christopher A, Funk, Jason A, Aoyama, Mineyoshi, Wine, Robert N

“…Localized tumor necrosis factor-α (TNFα) elevation has diverse effects in brain injury often attributed to signaling via TNFp55 or TNFp75 receptors. Both…”
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Accelerated recovery of renal mitochondrial and tubule homeostasis with SIRT1/PGC-1α activation following ischemia–reperfusion injury by Funk, Jason A., Schnellmann, Rick G.

“…Kidney ischemia–reperfusion (I/R) injury elicits cellular injury in the proximal tubule, and mitochondrial dysfunction is a pathological consequence of I/R…”
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SRT1720 induces mitochondrial biogenesis and rescues mitochondrial function after oxidant injury in renal proximal tubule cells by Funk, Jason A, Odejinmi, Sina, Schnellmann, Rick G

“…Mitochondrial biogenesis occurs under basal conditions and is an adaptive response initiated by cells to maintain energetic demands and metabolic homeostasis…”
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Mitochondrial Homeostasis in Acute Organ Failure by Stallons, L. Jay, Funk, Jason A., Schnellmann, Rick G.

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The type 1 interleukin 1 receptor is not required for the death of murine hippocampal dentate granule cells and microglia activation by Harry, G. Jean, Funk, Jason A, Lefebvre d'Hellencourt, Christian, McPherson, Christopher A, Aoyama, Mineyoshi

“…Abstract Alterations in inflammatory process, neuronal death, and glia response have been observed under manipulation of interleukin-1 (IL-1) and subsequent…”
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Mitochondrial Homeostasis in Acute Organ Failure by Stallons, L. Jay, Funk, Jason A., Schnellmann, Rick G.

“…The kidneys compose approximately 0.5 % of the body mass but consume about 10 % of the oxygen in cellular respiration. This discordance is due to the high…”
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Renal toxicity of domoic acid by Funk, Jason A, Janech, Michael G, Steele, Stacy L, Dillon, Joshua C, Bell, P Darwin

“…Abstract only Domoic acid (DA) is a glutamate analog and a characterized neurotoxicant. Outside of the CNS, glutamate receptors are also found in peripheral…”
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