Search Results - "Fung, K.P."

Synergistic effects of diosmetin with erythromycin against ABC transporter over-expressed methicillin-resistant Staphylococcus aureus (MRSA) RN4220/pUL5054 and inhibition of MRSA pyruvate kinase by Chan, Ben C.L., Ip, Margaret, Gong, H., Lui, S.L., See, Raymond H., Jolivalt, Claude, Fung, K.P., Leung, P.C., Reiner, Neil E., Lau, Clara B.S.

“…Increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA) worldwide with limited therapeutic options is a growing public health concern…”
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Isodon eriocalyx and its bioactive component Eriocalyxin B enhance cytotoxic and apoptotic effects of gemcitabine in pancreatic cancer by Li, L., Zhao, S.L., Yue, G.G.L., Wong, T.P., Pu, J.X., Sun, H.D., Fung, K.P., Leung, P.C., Han, Q.B., Lau, C.B.S., Leung, P.S.

“…Pancreatic cancer, associated with poor prognosis and low survival rate, has been the fourth leading cause of cancer-related death in the US. Although…”
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Mechanisms of the cerebral vasodilator actions of isoflavonoids of Gegen on rat isolated basilar artery by Deng, Y., Ng, E.S.K., Yeung, J.H.K., Kwan, Y.W., Lau, C.B.S., Koon, J.C.M., Zhou, L., Zuo, Z., Leung, P.C., Fung, K.P., Lam, F.F.Y.

“…Gegen (root of Pueraria lobata) is used in traditional Chinese medicine for treatment of cardiovascular diseases. In this study, the relaxant actions of three…”
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Effects of Radix Astragali and Radix Rehmanniae, the components of an anti-diabetic foot ulcer herbal formula, on metabolism of model CYP1A2, CYP2C9, CYP2D6, CYP2E1 and CYP3A4 probe substrates in pooled human liver microsomes and specific CYP isoforms by Or, Penelope M.Y., Lam, Francis F.Y., Kwan, Y.W., Cho, C.H., Lau, C.P., Yu, H., Lin, G., Lau, Clara B.S., Fung, K.P., Leung, P.C., Yeung, John H.K.

“…The present study investigated the effects of Radix Astragali (RA) and Radix Rehmanniae (RR), the major components of an anti-diabetic foot ulcer herbal…”
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Polyphyllin D induces mitochondrial fragmentation and acts directly on the mitochondria to induce apoptosis in drug-resistant HepG2 cells by Ong, Rose C.Y, Lei, Jin, Lee, Rebecca K.Y, Cheung, Jenny Y.N, Fung, K.P, Lin, Chinlon, Ho, H.P, Yu, Biao, Li, Ming, Kong, S.K

“…Abstract We previously showed that polyphyllin D (PD) produced a stronger apoptotic effect in R-HepG2 with multi-drug resistance (MDR) than that in its parent…”
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Efficacy and tolerability of a Chinese herbal medicine concoction for treatment of atopic dermatitis: a randomized, double-blind, placebo-controlled study by Hon, K.L.E., Leung, T.F., Ng, P.C., Lam, M.C.A., Kam, W.Y.C., Wong, K.Y., Lee, K.C.K., Sung, Y.T., Cheng, K.F., Fok, T.F., Fung, K.P., Leung, P.C.

“…Summary Background  There has been considerable interest in traditional Chinese herbal medicine (TCHM) as a treatment for atopic dermatitis (AD). A twice‐daily…”
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Pharmacological investigation on the wound healing effects of Radix Rehmanniae in an animal model of diabetic foot ulcer by Lau, T.W., Lam, F.F.Y., Lau, K.M., Chan, Y.W., Lee, K.M., Sahota, D.S., Ho, Y.Y., Fung, K.P., Leung, P.C., Lau, C.B.S.

“…Radix Rehmanniae (RR) has a very long history of usage in traditional Chinese medicine and is usually one of the principal herb found in many herbal formulae…”
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Investigation of the Combination Effects of Andrographis Paniculata With Chemotherapeutics for Esophageal Cancer Treatment by Li, L, Yue, G.G.L, Lee, J.M.K, Wong, E.C.W, Chan, K.M, Fung, K.P, Yu, J, Lau, C.B.S, Chiu, P.W.Y

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Pharmacological investigations of the anti-diabetic effect of Cortex Moutan and its active component paeonol by Lau, C.H., Chan, C.M., Chan, Y.W., Lau, K.M., Lau, T.W., Lam, F.C., Law, W.T., Che, C.T., Leung, P.C., Fung, K.P., Ho, Y.Y., Lau, C.B.S.

“…Cortex Moutan (CM, root bark of Paeonia suffruticosa Andr.) is one of the common herbs found in anti-diabetic traditional Chinese medicine formulae. To study…”
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Eriocalyxin B-induced apoptosis in pancreatic adenocarcinoma cells through thiol-containing antioxidant systems and downstream signalling pathways by Li, L, Yue, G G L, Pu, J X, Sun, H D, Fung, K P, Leung, P C, Han, Q B, Lau, C B S, Leung, P S

“…Thiol-containing antioxidant systems play an important role in regulating cellular redox homeostasis. Several anti-cancer agents act by targeting these systems…”
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Inhibition of cell proliferation and the action mechanisms of arsenic trioxide (As2O3) on human breast cancer cells by Chow, Stephanie K.Y., Chan, Judy Y.W., Fung, K.P.

“…Arsenic trioxide (As2O3) is one of the arsenic compounds found in nature. As2O3 has recently been used to treat patients suffering from retinoic acid receptor…”
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Cerebral vasodilator properties of Danshen and Gegen: A study of their combined efficacy and mechanisms of actions by Deng, Y., Ng, E.S.K., Kwan, Y.W., Lau, C.B.S., Cheung, D.W.S., Koon, J.C.M., Zhang, Z., Zuo, Z., Leung, P.C., Fung, K.P., Lam, F.F.Y.

“…Danshen and Gegen are two commonly used Chinese herbal medicines for treatment of cardiovascular diseases. The aim of the present study was to elucidate the…”
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Mechanisms of the relaxant effect of a Danshen and Gegen formulation on rat isolated cerebral basilar artery by Lam, F.F.Y., Deng, S.Y., Ng, E.S.K., Yeung, J.H.K., Kwan, Y.W., Lau, C.B.S., Koon, J.C.M., Zhou, L., Zuo, Z., Leung, P.C., Fung, K.P.

“…Danshen (root of Salvia miltiorrhiza) and Gegen (root of Pueraria lobata) are two herbs used in traditional Chinese medicine, most commonly for their putative…”
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Macrophage activation by polysaccharide biological response modifier isolated from Aloe vera L. var. chinensis (Haw.) Berg by Liu, C., Leung, M.Y.K., Koon, J.C.M., Zhu, L.F., Hui, Y.Z., Yu, B., Fung, K.P.

“…A mannose-rich polysaccharide biological response modifier (BRM), derived from Aloe vera L. var. chinensis (Haw.) Berg., was demonstrated to be a potent murine…”
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Induction of apoptosis by green tea catechins in human prostate cancer DU145 cells by Chung, L.Y., Cheung, T.C., Kong, S.K., Fung, K.P., Choy, Y.M., Chan, Z.Y., Kwok, T.T.

“…Green tea catechins (GTCs) including (−)-epigallocatechin-3-gallate (EGCG), (−)-epigallocatechin (EGC), (−)-epicatechin-3-gallate (ECG) and (−)-epicatechin…”
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Differential effect of Coriolus versicolor (Yunzhi) extract on cytokine production by murine lymphocytes in vitro by Ho, C.Y., Lau, Clara B.S., Kim, C.F., Leung, K.N., Fung, K.P., Tse, T.F., Chan, Helen H.L., Chow, Moses S.S.

“…Being one of the commonly used Chinese medicinal herbs, Coriolus versicolor (CV), also named as Yunzhi, was known to possess both anti-tumor and…”
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0428: Evaluation of the Renal Ultrasound Findings Associated with Melamine-Tainted Milk Products by Lau, Kevin C.H, Kan, Elaine Y.L, Lui, C.Y, Chong, Anida S.F, Tam, Godfrey K.F, Fung, K.P

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Antioxidation of human low density lipoprotein by unconjugated and conjugated bilirubins by Wu, Tai-Wing, Fung, K.P., Wu, Jun, Yang, Chih-Chin, Weisel, Richard D.

“…We demonstrate here that both unconjugated bilirubin (Bu) and conjugated bilirubin (Bc) can protect human low density lipoprotein (LDL) against oxidation by…”
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Effects Of CUF2 On Cytokine Release From Airway Cells Of Asthmatic Children by Wong, Y.O, Sung, R.Y.T, Li, A.M, Zhao, Y, Leung, T.F, Wong, R, Li, K, Fung, K.P

“…Conclusions We demonstrated that airway cells in sputum are partly active and only some cytokines (such as GM-CSF) responded to further stimulation, and the…”
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Effects of the Chinese Herbal Formula CUF2 on Cytokine Release from Human Mast Cell Line by Wong, Y.O, Sung, R.Y.T, Li, K, Zhao, Y, Li, A.M.C, Fung, K.P

“…CUF2 had inhibitory effects on interleukin (IL)-6, tumor necrosis factor- alpha (TNF-α) and granulocyte-macrophage colony-stimulating factor (GM-CSF)…”
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