Search Results - "Fung, Eva"
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Reader response: SYNGAP1 encephalopathy: A distinctive generalized developmental and epileptic encephalopathy
Published in Neurology (25-02-2020)Get full text
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Cyclometalated Palladium(II) N-Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression
Published in Angewandte Chemie International Edition (19-09-2016)“…Palladium(II) complexes are generally reactive toward substitution/reduction, and their biological applications are seldom explored. A new series of…”
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Luminescent organoplatinum(II) complexes containing bis(N-heterocyclic carbene) ligands selectively target the endoplasmic reticulum and induce potent photo-toxicity
Published in Chemical communications (Cambridge, England) (01-01-2013)“…A panel of luminescent platinum(II) complexes containing bidentate N-heterocyclic carbene ligands selectively localize to the endoplasmic reticulum (ER)…”
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4
β-catenin downregulates Dicer to promote ovarian cancer metastasis
Published in Oncogene (26-10-2017)“…Ovarian cancer is a nearly uniform lethal disease and its highly aggressive metastatic phenotype portends a poor prognosis. Lack of a well-controlled, relevant…”
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An Antitumor Bis(N‐Heterocyclic Carbene)Platinum(II) Complex That Engages Asparagine Synthetase as an Anticancer Target
Published in Angewandte Chemie International Edition (05-08-2019)“…New anticancer platinum(II) compounds with distinctive modes of action are appealing alternatives to combat the drug resistance and improve the efficacy of…”
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Improving Consistency and Accuracy of Neonatal Amplitude-Integrated Electroencephalography
Published in American journal of perinatology (01-02-2024)“…This study aimed to improve the utilization of amplitude-integrated electroencephalography (aEEG) in a neonatal unit by improving aEEG documentation, aEEG…”
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Controlled cellular redox, repressive hemin utilization and adaptive stress responses are crucial to metronidazole tolerance of Porphyromonas gingivalis persisters
Published in Journal of clinical periodontology (01-10-2018)“…Background Antimicrobial‐tolerant microbial persisters critically account for various infections and inflammation. This study identified the characteristics of…”
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Recessive mutations in POLR1C cause a leukodystrophy by impairing biogenesis of RNA polymerase III
Published in Nature communications (07-07-2015)“…A small proportion of 4H (Hypomyelination, Hypodontia and Hypogonadotropic Hypogonadism) or RNA polymerase III (POLR3)-related leukodystrophy cases are…”
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Expansion of the clinical and molecular spectrum of WWOX‐related epileptic encephalopathy
Published in American journal of medical genetics. Part A (01-03-2023)“…WWOX biallelic loss‐of‐function pathogenic single nucleotide variants (SNVs) and copy number variants (CNVs) including exonic deletions and duplications cause…”
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Anti-N-methyl-d-aspartate receptor encephalitis in children: Incidence and experience in Hong Kong
Published in Brain & development (Tokyo. 1979) (01-06-2018)“…The study aims to analyze the incidence, clinical features, investigation findings and treatment outcomes of anti-N-methyl-d-aspartate receptor encephalitis in…”
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Review and update of the Hong Kong Epilepsy Guideline on status epilepticus
Published in Hong Kong medical journal = Xianggang yi xue za zhi (01-02-2017)“…Convulsive status epilepticus is the most extreme form of seizure. It is a medical and neurological emergency that requires prompt and appropriate treatment…”
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Ketamine use for super-refractory status epilepticus in children
Published in Hong Kong medical journal = Xianggang yi xue za zhi (01-12-2020)Get full text
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Exome sequencing in paediatric patients with movement disorders
Published in Orphanet journal of rare diseases (15-01-2021)“…Movement disorders are a group of heterogeneous neurological diseases including hyperkinetic disorders with unwanted excess movements and hypokinetic disorders…”
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Toward Proteome-Scale Identification and Quantification of Isoaspartyl Residues in Biological Samples
Published in Journal of proteome research (01-10-2009)“…Deamidation of asparaginyl and isomerization of aspartyl residues in proteins produce a mixture of aspartyl and isoaspartyl residues, the latter being involved…”
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Infantile to late adulthood onset facioscapulohumeral dystrophy type 1: a case series
Published in Hong Kong medical journal = Xianggang yi xue za zhi (01-12-2021)“…A 14-year-old boy who first presented with symptoms of facioscapulohumeral muscular dystrophy type 1 from age 11 years. (a-c)Axial T1-weighted and (d-f) short…”
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Risk of tuberculosis in patients with spondyloarthritis: data from a centralized electronic database in Hong Kong
Published in BMC musculoskeletal disorders (10-12-2020)“…Tuberculosis (TB) is one of the most infectious comorbidities in spondyloarthritis (SpA). Our goals were to determine the crude incidence rate of and risk…”
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Deep brain stimulation of the anterior nucleus of the thalamus for drug‐resistant epilepsy: Long‐term efficacy and outcomes from a prospective cohort
Published in Surgical practice (01-02-2023)“…Aim The anterior nucleus of the thalamus (ANT) has been one of the deep brain stimulation (DBS) targets for drug‐resistant epilepsy. This study aims to…”
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Bifurcating Fragmentation Behavior of Gas-Phase Tryptic Peptide Dications in Collisional Activation
Published in Journal of the American Society for Mass Spectrometry (01-12-2008)“…Collision-activated dissociation (CAD) of tryptic peptides is a cornerstone of mass spectrometry-based proteomics research. Principal component analysis of a…”
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Guillain-Barré syndrome in children – High occurrence of Miller Fisher syndrome in East Asian region
Published in Brain & development (Tokyo. 1979) (01-11-2022)“…Guillain-Barré syndrome (GBS) is a rare acquired immune-mediated polyneuropathy. Updated population-based data concerning paediatric GBS is needed. Paediatric…”
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Electron Ionization Dissociation of Singly and Multiply Charged Peptides
Published in Journal of the American Chemical Society (29-07-2009)“…A new tandem mass spectrometry technique, electron ionization dissociation (EID), employs irradiation of trapped cations [M + nH] n+ (n ≥ 1) by fast electrons…”
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