Search Results - "Fung, Cyra"

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  1. 1
    FG-3019, a Human Monoclonal Antibody Recognizing Connective Tissue Growth Factor, is Subject to Target-Mediated Drug Disposition

    FG-3019, a Human Monoclonal Antibody Recognizing Connective Tissue Growth Factor, is Subject to Target-Mediated Drug Disposition by Brenner, Mitchell C., Krzyzanski, Wojciech, Chou, James Z., Signore, Pierre E., Fung, Cyra K., Guzman, David, Li, Dongxia, Zhang, Weihua, Olsen, David R., Nguyen, Viet-Tam L., Koo, Carolyn W., Sternlicht, Mark D., Lipson, Kenneth E.

    Published in Pharmaceutical research (01-08-2016)
    “…Purpose To evaluate and model the pharmacokinetic and pharmacodynamic behavior in rats of FG-3019, a human monoclonal antibody targeting connective tissue…”
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  2. 2
    Combination treatment with tenapanor and sevelamer synergistically reduces urinary phosphorus excretion in rats

    Combination treatment with tenapanor and sevelamer synergistically reduces urinary phosphorus excretion in rats by King, Andrew J, Kohler, Jill, Fung, Cyra, Jiang, Zhengfeng, Quach, Allison, Kumaraswamy, Padmapriya, Chertow, Glenn M, Rosenbaum, David P

    “…The majority of patients with chronic kidney disease (CKD) receiving dialysis do not achieve target serum phosphorus concentrations, despite treatment with…”
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  3. 3
    RDX013, a Novel, Oral, Small Molecule Being Developed for Treatment of Hyperkalemia, Increases Colonic Secretion and Fecal Excretion of Potassium: PO1136

    RDX013, a Novel, Oral, Small Molecule Being Developed for Treatment of Hyperkalemia, Increases Colonic Secretion and Fecal Excretion of Potassium: PO1136 by Kozuka, Kenji, Siegel, Matthew, King, Andrew J., Kohler, Jill N., Jiang, Zhengfeng, Quach, Allison, Fung, Cyra, He, Ying, Kumaraswamy, Padmapriya, He, Limin, Le, Cathy M., Tran, Catarina, Caldwell, Jeremy, Rosenbaum, David P., Jacobs, Jeffrey

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  4. 4
    Sa1555 - Inhibition of Gastrointestinal (GI) Nhe3 Normalizes GI Transit in Models of Opioid-Induced Constipation, Multiple Sclerosis and Cystic Fibrosis

    Sa1555 - Inhibition of Gastrointestinal (GI) Nhe3 Normalizes GI Transit in Models of Opioid-Induced Constipation, Multiple Sclerosis and Cystic Fibrosis by King, Andrew J., Fung, Cyra, Nguyen, Henry, White, Kathy, Dragoli, Dean, Hodges, Craig A., Caldwell, Jeremy S.

    Published in Gastroenterology (New York, N.Y. 1943) (01-05-2018)
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  5. 5
    Abstract 16852: Inhibition of Hypoxia-Inducible Factor Prolyl Hydroxylase Reduces Infarct Size and Improves Cardiac Function in a Rat Model of Myocardial Ischemia Reperfusion Injury

    Abstract 16852: Inhibition of Hypoxia-Inducible Factor Prolyl Hydroxylase Reduces Infarct Size and Improves Cardiac Function in a Rat Model of Myocardial Ischemia Reperfusion Injury by Signore, Pierre, Wei, Zhihua, Fung, Cyra, Russell, Loren, Arend, Michael, Flippin, Lee, Walkinshaw, Gail, del Balzo, Ughetta

    Published in Circulation (New York, N.Y.) (22-11-2011)
    “…Abstract only Hypoxia-inducible factor (HIF) has been shown to have cardioprotective effects when stabilized prior to a cardiac ischemic event. In the present…”
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