Search Results - "Funakoshi, Yuji"

Ubiquitin-specific protease TRE17/USP6 promotes tumor cell invasion through the regulation of glycoprotein CD147 intracellular trafficking by Ogura, Yukino, Ohbayashi, Norihiko, Kanaho, Yasunori, Kawaguchi, Atsushi, Funakoshi, Yuji

“…Disordered expression and distribution of plasma membrane proteins at the cell surface leads to diverse malignant phenotypes in tumors, including cell…”
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Molecular Mechanisms of N-Formyl-Methionyl-Leucyl-Phenylalanine-Induced Superoxide Generation and Degranulation in Mouse Neutrophils: Phospholipase D Is Dispensable by Sato, Takanobu, Hongu, Tsunaki, Sakamoto, Megumi, Funakoshi, Yuji, Kanaho, Yasunori

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Regulation of PIP5K activity by Arf6 and its physiological significance by Funakoshi, Yuji, Hasegawa, Hiroshi, Kanaho, Yasunori

“…The phospholipid kinase phosphatidylinositol 4‐phosphate 5‐kinase (PIP5K) catalyzes the phosphorylation of the membrane phospholipid phosphatidylinositol…”
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Phospholipase D2 promotes disease progression of renal cell carcinoma through the induction of angiogenin by Kandori, Shuya, Kojima, Takahiro, Matsuoka, Taeko, Yoshino, Takayuki, Sugiyama, Aiko, Nakamura, Eijiro, Shimazui, Toru, Funakoshi, Yuji, Kanaho, Yasunori, Nishiyama, Hiroyuki

“…A hallmark of clear cell renal cell carcinoma (ccRCC) is the presence of intracellular lipid droplets (LD) and it is assumed that phosphatidic acid (PA)…”
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Mechanism of mRNA deadenylation: evidence for a molecular interplay between translation termination factor eRF3 and mRNA deadenylases by Funakoshi, Yuji, Doi, Yusuke, Hosoda, Nao, Uchida, Naoyuki, Osawa, Masanori, Shimada, Ichio, Tsujimoto, Masafumi, Suzuki, Tsutomu, Katada, Toshiaki, Hoshino, Shin-ichi

“…In eukaryotes, shortening of the 3'-poly(A) tail is the rate-limiting step in the degradation of most mRNAs, and two major mRNA deadenylase…”
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Assessment of Arf6 Deletion in PLB-985 Differentiated in Neutrophil-Like Cells and in Mouse Neutrophils: Impact on Adhesion and Migration by Bourgoin, Sylvain G., Kanaho, Yasunori, Funakoshi, Yuji, Hongu, Tsunaki, Rollet-Labelle, Emmanuelle, Davis, Lynn, Gamara, Jouda, Aoudjit, Fawzi

“…Chemoattractant sensing, adhesiveness, and migration are critical events underlying the recruitment of neutrophils (PMNs) to sites of inflammation or…”
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Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase by Hosoda, Nao, Funakoshi, Yuji, Hirasawa, Masato, Yamagishi, Ryota, Asano, Yukako, Miyagawa, Ryu, Ogami, Koichi, Tsujimoto, Masafumi, Hoshino, Shin-ichi

“…Tob is a member of the anti‐proliferative protein family, which functions in transcription and mRNA decay. We have previously demonstrated that Tob is involved…”
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Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes by Lee, SangJoon, Ishitsuka, Akari, Kuroki, Takahiro, Lin, Yu-Hsien, Shibuya, Akira, Hongu, Tsunaki, Funakoshi, Yuji, Kanaho, Yasunori, Nagata, Kyosuke, Kawaguchi, Atsushi

“…Asthma is a chronic inflammatory disease of the airways associated with excess production of Th2 cytokines and lung eosinophil accumulation. This inflammatory…”
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Activation of the Small G Protein Arf6 by Dynamin2 through Guanine Nucleotide Exchange Factors in Endocytosis by Okada, Risa, Yamauchi, Yohei, Hongu, Tsunaki, Funakoshi, Yuji, Ohbayashi, Norihiko, Hasegawa, Hiroshi, Kanaho, Yasunori

“…The small G protein Arf6 and the GTPase dynamin2 (Dyn2) play key roles in clathrin-mediated endocytosis (CME). However, their functional relationship remains…”
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Translation Termination Factor eRF3 Mediates mRNA Decay through the Regulation of Deadenylation by Hosoda, Nao, Kobayashi, Tetsuo, Uchida, Naoyuki, Funakoshi, Yuji, Kikuchi, Yoshiko, Hoshino, Shinichi, Katada, Toshiaki

“…Messenger RNA decay, which is a regulated process intimately linked to translation, begins with the deadenylation of the poly(A) tail at the 3′ end. However,…”
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Molecular mechanisms of fMLP-induced superoxide generation and degranulation in mouse neutrophils by Kanaho, Yasunori, Sato, Takanobu, Hongu, Tsunaki, Funakoshi, Yuji

“…In this manuscript, involvement of PLD in fMLP-induced superoxide generation and degranulation were re-investigated using PLD−/− neutrophils, and the molecular…”
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The scaffold protein JIP3 functions as a downstream effector of the small GTPase ARF6 to regulate neurite morphogenesis of cortical neurons by Suzuki, Atsushi, Arikawa, Chihiro, Kuwahara, Yuji, Itoh, Kouichi, Watanabe, Masatomo, Watanabe, Hiroshi, Suzuki, Teruhiko, Funakoshi, Yuji, Hasegawa, Hiroshi, Kanaho, Yasunori

“…The small GTPase ADP-ribosylation factor 6 (ARF6) plays crucial roles in a wide variety of cell functions. To better understand the molecular mechanisms of…”
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Coupling of Hydrodynamic and Wave Models: Case Study for Hurricane Floyd (1999) Hindcast by Funakoshi, Yuji, Hagen, Scott C, Bacopoulos, Peter

“…This paper demonstrates a practical application of coupling a hydrodynamic model with a wave model for the calculation of storm tide elevations in the St…”
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Tissue‐ and development‐dependent expression of the small GTPase Arf6 in mice by Akiyama, Masahiro, Zhou, Miao, Sugimoto, Rika, Hongu, Tsunaki, Furuya, Momoko, Funakoshi, Yuji, Kato, Mitsuyasu, Hasegawa, Hiroshi, Kanaho, Yasunori

“…The small GTPase Arf6 is a member of the Arf (ADP‐ribosylation factor) family. Although the function of Arf6 has been heavily studied at the cellular level,…”
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The GTP-binding Release Factor eRF3 as a Key Mediator Coupling Translation Termination to mRNA Decay by Kobayashi, Tetsuo, Funakoshi, Yuji, Hoshino, Shin-Ichi, Katada, Toshiaki

“…GTP is essential for eukaryotic translation termination, where the release factor 3 (eRF3) complexed with eRF1 is involved as the guanine nucleotide-binding…”
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Phosphatidylinositol 4-Phosphate 5-Kinase Is Indispensable for Mouse Spermatogenesis1 by Hasegawa, Hiroshi, Noguchi, Junko, Yamashita, Misuzu, Okada, Risa, Sugimoto, Rika, Furuya, Momoko, Unoki, Takamitsu, Funakoshi, Yuji, Baba, Tadashi, Kanaho, Yasunori

“…The lipid kinase phosphatidylinositol 4-phosphate 5-kinase (PIP5K) produces a versatile signaling phospholipid, phosphatidylinositol 4,5-bisphosphate. Three…”
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NMDA receptor-mediated PIP5K activation to produce PI(4,5)P₂ is essential for AMPA receptor endocytosis during LTD by Unoki, Takamitsu, Matsuda, Shinji, Kakegawa, Wataru, Van, Ngo Thai Bich, Kohda, Kazuhisa, Suzuki, Atsushi, Funakoshi, Yuji, Hasegawa, Hiroshi, Yuzaki, Michisuke, Kanaho, Yasunori

“…NMDA receptor activation leads to clathrin-dependent endocytosis of postsynaptic AMPA receptors. Although this process controls long-term depression (LTD)…”
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Assessing the Performance of a Northern Gulf of Mexico Tidal Model Using Satellite Imagery by Medeiros, Stephen, Hagen, Scott, Chaouch, Naira, Feyen, Jesse, Temimi, Marouane, Weishampel, John, Funakoshi, Yuji, Khanbilvardi, Reza

“…Tidal harmonic analysis simulations along with simulations spanning four specific historical time periods in 2003 and 2004 were conducted to test the…”
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PLD1 promotes tumor invasion by regulation of MMP-13 expression via NF-κB signaling in bladder cancer by Nagumo, Yoshiyuki, Kandori, Shuya, Tanuma, Kozaburo, Nitta, Satoshi, Chihara, Ichiro, Shiga, Masanobu, Hoshi, Akio, Negoro, Hiromitsu, Kojima, Takahiro, Mathis, Bryan J., Funakoshi, Yuji, Nishiyama, Hiroyuki

“…Invasion of bladder cancer (BC) cells from the mucosa into the muscle layer is canonical for BC progression while phospholipase D isoform 1 (PLD1) is known to…”
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Phospholipase D signalling and its involvement in neurite outgrowth by Kanaho, Yasunori, Funakoshi, Yuji, Hasegawa, Hiroshi

“…Since the original discovery and structural elucidation of the mammalian phospholipase D (PLD), its potential to play a role in the lipid signalling pathway…”
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