Search Results - "Funai, Yuta"

Quantitative analysis of gastrointestinal fluid absorption and secretion to estimate luminal fluid dynamics in rats by Funai, Yuta, Ichijo, Kazuki, Suzuki, Satoru, Tateishi, Yuta, Inoue, Katsuhisa, Tamai, Ikumi, Shirasaka, Yoshiyuki

“…The drug absorption profile is dependent on the luminal drug concentration, which in turn is influenced by the gastrointestinal (GI) fluid dynamics. In the…”
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Effect of Osmolality on the Pharmacokinetic Interaction between Apple Juice and Atenolol in Rats by Funai, Yuta, Shirasaka, Yoshiyuki, Ishihara, Marika, Takemura, Miyuki, Ichijo, Kazuki, Kishimoto, Hisanao, Inoue, Katsuhisa

“…A recent clinical study reported that the ingestion of apple juice (AJ) markedly reduced the plasma concentration of atenolol; however, our in vitro study…”
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Osmolality of Orally Administered Solutions Influences Luminal Water Volume and Drug Absorption in Intestine by Ichijo, Kazuki, Oda, Rika, Ishihara, Marika, Okada, Ren, Moteki, Yuri, Funai, Yuta, Horiuchi, Takuya, Kishimoto, Hisanao, Shirasaka, Yoshiyuki, Inoue, Katsuhisa

“…Intestinal water absorption is reportedly influenced by luminal osmolality. In this study, we examined whether differences in the osmolality of the vehicle…”
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P218 - Quantitative prediction of oral drug absorption by kinetically analyzing gastrointestinal water dynamics by Shirasaka, Yoshiyuki, Suzuki, Satoru, Funai, Yuta, Takemura, Miyuki, Tateishi, Yuta, Ichijo, Kazuki, Okada, Ren, Ishihara, Marika, Oda, Rika, Eguchi, Akari, Kishimoto, Hisanao, Inoue, Katsuhisa

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Effect of ingested fluid volume and solution osmolality on intestinal drug absorption: Impact on drug interaction with beverages by Funai, Yuta, Takemura, Miyuki, Inoue, Katsuhisa, Shirasaka, Yoshiyuki

“…It was recently shown that osmolality-dependent fluid movement is a significant factor causing the clinically observed apple juice (AJ)-atenolol interaction…”
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3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV‑2 Agents by Konno, Sho, Kobayashi, Kiyotaka, Senda, Miki, Funai, Yuta, Seki, Yuta, Tamai, Ikumi, Schäkel, Laura, Sakata, Kyousuke, Pillaiyar, Thanigaimalai, Taguchi, Akihiro, Taniguchi, Atsuhiko, Gütschow, Michael, Müller, Christa E, Takeuchi, Koh, Hirohama, Mikako, Kawaguchi, Atsushi, Kojima, Masaki, Senda, Toshiya, Shirasaka, Yoshiyuki, Kamitani, Wataru, Hayashi, Yoshio

“…The novel coronavirus, SARS-CoV-2, has been identified as the causative agent for the current coronavirus disease (COVID-19) pandemic. 3CL protease (3CLpro)…”
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