Search Results - "Fumo, Gerard"

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  1. 1
    17-Allylamino-17-demethoxygeldanamycin (17-AAG) is effective in down-regulating mutated, constitutively activated KIT protein in human mast cells

    17-Allylamino-17-demethoxygeldanamycin (17-AAG) is effective in down-regulating mutated, constitutively activated KIT protein in human mast cells by Fumo, Gerard, Akin, Cem, Metcalfe, Dean D., Neckers, Len

    Published in Blood (01-02-2004)
    “…Mutations in the proto-oncogene c-kit cause constitutive kinase activity of its product, KIT protein, and are associated with human mastocytosis and…”
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  2. 2
    A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib

    A novel form of mastocytosis associated with a transmembrane c-kit mutation and response to imatinib by Akin, Cem, Fumo, Gerard, Yavuz, Akif S., Lipsky, Peter E., Neckers, Len, Metcalfe, Dean D.

    Published in Blood (15-04-2004)
    “…Mutational analysis of the c-kit gene in a patient with a previously undescribed variant of mast cell disease revealed a germline mutation, Phe522Cys, within…”
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    A method of directed random mutagenesis of the yeast chromosome shows that the iso-1-cytochrome c heme ligand His18 is essential

    A method of directed random mutagenesis of the yeast chromosome shows that the iso-1-cytochrome c heme ligand His18 is essential by Fumo, Gerard, Spitzer, Jennifer S., Fetrow, Jacquelyn S.

    Published in Gene (16-10-1995)
    “…A method to perform site-directed random mutagenesis directly in the yeast chromosomal DNA at the iso-1-cytochrome c-encoding gene locus ( CYCI) is described…”
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