Search Results - "Fumene Feruglio, Paolo"

Myocardial Infarction Activates CCR2+ Hematopoietic Stem and Progenitor Cells by Dutta, Partha, Sager, Hendrik B., Stengel, Kristy R., Naxerova, Kamila, Courties, Gabriel, Saez, Borja, Silberstein, Lev, Heidt, Timo, Sebas, Matthew, Sun, Yuan, Wojtkiewicz, Gregory, Feruglio, Paolo Fumene, King, Kevin, Baker, Joshua N., van der Laan, Anja M., Borodovsky, Anna, Fitzgerald, Kevin, Hulsmans, Maarten, Hoyer, Friedrich, Iwamoto, Yoshiko, Vinegoni, Claudio, Brown, Dennis, Di Carli, Marcelo, Libby, Peter, Hiebert, Scott W., Scadden, David T., Swirski, Filip K., Weissleder, Ralph, Nahrendorf, Matthias

“…Following myocardial infarction (MI), myeloid cells derived from the hematopoietic system drive a sharp increase in systemic leukocyte levels that correlates…”
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Hybrid PET-optical imaging using targeted probes by Nahrendorf, Matthias, Keliher, Edmund, Marinelli, Brett, Waterman, Peter, Feruglio, Paolo Fumene, Fexon, Lioubov, Pivovarov, Misha, Swirski, Filip K., Pittet, Mikael J., Vinegoni, Claudio, Weissleder, Ralph, Wilson, Brian

“…Fusion imaging of radionuclide-based molecular (PET) and structural data [x-ray computed tomography (CT)] has been firmly established. Here we show that…”
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WNT5A/JNK and FGF/MAPK Pathways Regulate the Cellular Events Shaping the Vertebrate Limb Bud by Gros, Jerome, Hu, Jimmy Kuang-Hsien, Vinegoni, Claudio, Feruglio, Paolo Fumene, Weissleder, Ralph, Tabin, Clifford J.

“…The vertebrate limb is a classical model for understanding patterning of three-dimensional structures during embryonic development. Although decades of…”
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Real-time in vivo imaging of the beating mouse heart at microscopic resolution by Lee, Sungon, Vinegoni, Claudio, Feruglio, Paolo Fumene, Fexon, Lyuba, Gorbatov, Rostic, Pivoravov, Misha, Sbarbati, Andrea, Nahrendorf, Matthias, Weissleder, Ralph

“…Real-time imaging of moving organs and tissues at microscopic resolutions represents a major challenge in studying the complex biology of live animals. Here we…”
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High Dynamic Range Fluorescence Imaging by Vinegoni, Claudio, Fumene Feruglio, Paolo, Weissleder, Ralph

“…Fluorescence acquisition and image display over a high dynamic range is highly desirable. However, the limited dynamic range of current photodetectors and…”
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Mapping molecular agents distributions in whole mice hearts using born-normalized optical projection tomography by Vinegoni, Claudio, Fumene Feruglio, Paolo, Razansky, Daniel, Gorbatov, Rostic, Ntziachristos, Vasilis, Sbarbati, Andrea, Nahrendorf, Matthias, Weissleder, Ralph

“…To date there is a lack of tools to map the spatio-temporal dynamics of diverse cells in experimental heart models. Conventional histology is labor intensive…”
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Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease by McAlpine, Cameron S., Park, Joseph, Griciuc, Ana, Kim, Eunhee, Choi, Se Hoon, Iwamoto, Yoshiko, Kiss, Máté G., Christie, Kathleen A., Vinegoni, Claudio, Poller, Wolfram C., Mindur, John E., Chan, Christopher T., He, Shun, Janssen, Henrike, Wong, Lai Ping, Downey, Jeffrey, Singh, Sumnima, Anzai, Atsushi, Kahles, Florian, Jorfi, Mehdi, Feruglio, Paolo Fumene, Sadreyev, Ruslan I., Weissleder, Ralph, Kleinstiver, Benjamin P., Nahrendorf, Matthias, Tanzi, Rudolph E., Swirski, Filip K.

“…Communication within the glial cell ecosystem is essential for neuronal and brain health 1 – 3 . The influence of glial cells on the accumulation and clearance…”
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Diminished Reactive Hematopoiesis and Cardiac Inflammation in a Mouse Model of Recurrent Myocardial Infarction by Cremer, Sebastian, Schloss, Maximilian J., Vinegoni, Claudio, Foy, Brody H., Zhang, Shuang, Rohde, David, Hulsmans, Maarten, Fumene Feruglio, Paolo, Schmidt, Stephen, Wojtkiewicz, Greg, Higgins, John M., Weissleder, Ralph, Swirski, Filip K., Nahrendorf, Matthias

“…Recurrent myocardial infarction (MI) is common in patients with coronary artery disease and is associated with high mortality. Long-term reprogramming of…”
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Advanced Motion Compensation Methods for Intravital Optical Microscopy by Vinegoni, Claudio, Sungon Lee, Feruglio, Paolo Fumene, Weissleder, Ralph

“…Intravital microscopy has emerged in the recent decade as an indispensible imaging modality for the study of the microdynamics of biological processes in live…”
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Fluorescence microscopy tensor imaging representations for large-scale dataset analysis by Vinegoni, Claudio, Fumene Feruglio, Paolo, Courties, Gabriel, Schmidt, Stephen, Hulsmans, Maarten, Lee, Sungon, Wang, Rui, Sosnovik, David, Nahrendorf, Matthias, Weissleder, Ralph

“…Understanding complex biological systems requires the system-wide characterization of cellular and molecular features. Recent advances in optical imaging…”
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Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response by Giedt, Randy J., Fumene Feruglio, Paolo, Pathania, Divya, Yang, Katherine S., Kilcoyne, Aoife, Vinegoni, Claudio, Mitchison, Timothy J., Weissleder, Ralph

“…Mitochondria, which are essential organelles in resting and replicating cells, can vary in number, mass and shape. Past research has primarily focused on…”
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Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging by Vinegoni, Claudio, Fumene Feruglio, Paolo, Brand, Christian, Lee, Sungon, Nibbs, Antoinette E, Stapleton, Shawn, Shah, Sunil, Gryczynski, Ignacy, Reiner, Thomas, Mazitschek, Ralph, Weissleder, Ralph

“…This protocol enables accurate models of the pharmacokinetics and pharmacodynamics of drug action to be determined, using simultaneous dual-channel two-photon…”
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In Vivo Imaging of Drug-Induced Mitochondrial Outer Membrane Permeabilization at Single-Cell Resolution by EARLEY, Sarah, VINEGONI, Claudio, DUNHAM, Joshua, GORBATOV, Rostic, FERUGLIO, Paolo Fumene, WEISSLEDER, Ralph

“…Observing drug responses in the tumor microenvironment in vivo can be technically challenging. As a result, cellular responses to molecularly targeted cancer…”
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Improved intravital microscopy via synchronization of respiration and holder stabilization by Lee, Sungon, Vinegoni, Claudio, Feruglio, Paolo Fumene, Weissleder, Ralph

“…A major challenge in high-resolution intravital confocal and multiphoton microscopy is physiologic tissue movement during image acquisition. Of the various…”
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Sequential average segmented microscopy for high signal-to-noise ratio motion-artifact-free in vivo heart imaging by Vinegoni, Claudio, Lee, Sungon, Feruglio, Paolo Fumene, Marzola, Pasquina, Nahrendorf, Matthias, Weissleder, Ralph

“…In vivo imaging is often severely compromised by cardiovascular and respiratory motion. Highly successful motion compensation techniques have been developed…”
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High throughput transmission optical projection tomography using low cost graphics processing unit by Vinegoni, Claudio, Fexon, Lyuba, Feruglio, Paolo Fumene, Pivovarov, Misha, Figueiredo, Jose-Luiz, Nahrendorf, Matthias, Pozzo, Antonio, Sbarbati, Andrea, Weissleder, Ralph

“…We implement the use of a graphics processing unit (GPU) in order to achieve real time data processing for high-throughput transmission optical projection…”
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Imaging of molecular probe activity with Born-normalized fluorescence optical projection tomography by Vinegoni, Claudio, Fumene Feruglio, Paolo, Cortez-Retamozo, Virna, Razansky, Daniel, Medoff, Benjamin D, Ntziachristos, Vasilis, Sbarbati, Andrea, Pittet, Mikael, Weissleder, Ralph

“…Optical projection tomography is a new ex vivo imaging technique that allows imaging of whole organs in three dimensions at high spatial resolutions. In this…”
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Noise suppressed, multifocus image fusion for enhanced intraoperative navigation by Feruglio, Paolo Fumene, Vinegoni, Claudio, Fexon, Lioubov, Thurber, Greg, Sbarbati, Andrea, Weissleder, Ralph

“…Current intraoperative imaging systems are typically not able to provide ‘sharp’ images over entire large areas or entire organs. Distinct structures such as…”
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Fluorescence anisotropy imaging in drug discovery by Vinegoni, Claudio, Feruglio, Paolo Fumene, Gryczynski, Ignacy, Mazitschek, Ralph, Weissleder, Ralph

“…Non-invasive measurement of drug-target engagement can provide critical insights in the molecular pharmacology of small molecule drugs. Fluorescence…”
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Extended dynamic range imaging for noise mitigation in fluorescence anisotropy imaging by Feruglio, Paolo Fumene, Vinegoni, Claudio, Weissleder, Ralph

“…Significance: Fluorescence polarization (FP) and fluorescence anisotropy (FA) microscopy are powerful imaging techniques that allow to translate the common FP…”
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