Search Results - "Fumagalli, Giorgio G."

MRI visual rating scales in the diagnosis of dementia: evaluation in 184 post-mortem confirmed cases by Harper, Lorna, Fumagalli, Giorgio G, Barkhof, Frederik, Scheltens, Philip, O'Brien, John T, Bouwman, Femke, Burton, Emma J, Rohrer, Jonathan D, Fox, Nick C, Ridgway, Gerard R, Schott, Jonathan M

“…Accurately distinguishing between different degenerative dementias during life is challenging but increasingly important with the prospect of disease-modifying…”
Get full text

MiRNA Profiling in Plasma Neural-Derived Small Extracellular Vesicles from Patients with Alzheimer's Disease by Serpente, Maria, Fenoglio, Chiara, D'Anca, Marianna, Arcaro, Marina, Sorrentino, Federica, Visconte, Caterina, Arighi, Andrea, Fumagalli, Giorgio G, Porretti, Laura, Cattaneo, Alessandra, Ciani, Miriam, Zanardini, Roberta, Benussi, Luisa, Ghidoni, Roberta, Scarpini, Elio, Galimberti, Daniela

“…Small extracellular vesicles (EVs) are able to pass from the central nervous system (CNS) into peripheral blood and contain molecule markers of their parental…”
Get full text

miRNA Expression Is Increased in Serum from Patients with Semantic Variant Primary Progressive Aphasia by Serpente, Maria, Ghezzi, Laura, Fenoglio, Chiara, Buccellato, Francesca R, Fumagalli, Giorgio G, Rotondo, Emanuela, Arcaro, Marina, Arighi, Andrea, Galimberti, Daniela

“…Primary progressive aphasia (PPA) damages the parts of the brain that control speech and language. There are three clinical PPA variants: nonfluent/agrammatic…”
Get full text

Testing the 2018 NIA-AA research framework in a retrospective large cohort of patients with cognitive impairment: from biological biomarkers to clinical syndromes by Carandini, Tiziana, Arighi, Andrea, Sacchi, Luca, Fumagalli, Giorgio G, Pietroboni, Anna M, Ghezzi, Laura, Colombi, Annalisa, Scarioni, Marta, Fenoglio, Chiara, De Riz, Milena A, Marotta, Giorgio, Scarpini, Elio, Galimberti, Daniela

“…According to the 2018 NIA-AA research framework, Alzheimer's disease (AD) is not defined by the clinical consequences of the disease, but by its underlying…”
Get full text

Amyloid PET imaging and dementias: potential applications in detecting and quantifying early white matter damage by Pietroboni, Anna M, Colombi, Annalisa, Carandini, Tiziana, Sacchi, Luca, Fenoglio, Chiara, Marotta, Giorgio, Arighi, Andrea, De Riz, Milena A, Fumagalli, Giorgio G, Castellani, Massimo, Bozzali, Marco, Scarpini, Elio, Galimberti, Daniela

“…Positron emission tomography (PET) with amyloid tracers (amy-PET) allows the quantification of pathological amyloid deposition in the brain tissues, including…”
Get full text

A Novel Automated Chemiluminescence Method for Detecting Cerebrospinal Fluid Amyloid-Beta 1-42 and 1-40, Total Tau and Phosphorylated-Tau: Implications for Improving Diagnostic Performance in Alzheimer's Disease by Arcaro, Marina, Fenoglio, Chiara, Serpente, Maria, Arighi, Andrea, Fumagalli, Giorgio G, Sacchi, Luca, Floro, Stefano, D'Anca, Marianna, Sorrentino, Federica, Visconte, Caterina, Perego, Alberto, Scarpini, Elio, Galimberti, Daniela

“…Recently, a fully automated instrument for the detection of the Cerebrospinal Fluid (CSF) biomarker for Alzheimer’s disease (AD) (low concentration of…”
Get full text

Parieto-occipital sulcus widening differentiates posterior cortical atrophy from typical Alzheimer disease by Fumagalli, Giorgio G., Basilico, Paola, Arighi, Andrea, Mercurio, Matteo, Scarioni, Marta, Carandini, Tiziana, Colombi, Annalisa, Pietroboni, Anna M., Sacchi, Luca, Conte, Giorgio, Scola, Elisa, Triulzi, Fabio, Scarpini, Elio, Galimberti, Daniela

“…•Parieto-occipital sulcus visual rating scale can distinguish PCA from typical AD.•Visual rating scales have been validated using VBM and Brainvisa…”
Get full text

Profiling of ubiquitination pathway genes in peripheral cells from patients with frontotemporal dementia due to C9ORF72 and GRN mutations by Serpente, Maria, Fenoglio, Chiara, Cioffi, Sara M G, Bonsi, Rossana, Arighi, Andrea, Fumagalli, Giorgio G, Ghezzi, Laura, Scarpini, Elio, Galimberti, Daniela

“…We analysed the expression levels of 84 key genes involved in the regulated degradation of cellular protein by the ubiquitin-proteasome system in peripheral…”
Get full text

Diogenes syndrome in dementia: a case report by Sacchi, Luca, Rotondo, Emanuela, Pozzoli, Sara, Fiorentini, Alessio, Schinco, Giuseppina, Mandelli, Clara, Coppola, Carlotta, Fumagalli, Giorgio G., Carandini, Tiziana, Pietroboni, Anna M., Galimberti, Daniela, Triulzi, Fabio, Marotta, Giorgio, Scarpini, Elio, Cesari, Matteo, Brambilla, Paolo, Arighi, Andrea

“…Diogenes syndrome is a neurobehavioural syndrome characterised by domestic squalor, hoarding and lack of insight. It is an uncommon but high-mortality…”
Get full text

Alzheimer's Disease Diagnosis: Discrepancy between Clinical, Neuroimaging, and Cerebrospinal Fluid Biomarkers Criteria in an Italian Cohort of Geriatric Outpatients: A Retrospective Cross-sectional Study by Dolci, Giulia A M, Damanti, Sarah, Scortichini, Valeria, Galli, Alessandro, Rossi, Paolo D, Abbate, Carlo, Arosio, Beatrice, Mari, Daniela, Arighi, Andrea, Fumagalli, Giorgio G, Scarpini, Elio, Inglese, Silvia, Marcucci, Maura

“…The role of cerebrospinal fluid (CSF) biomarkers, and neuroimaging in the diagnostic process of Alzheimer's disease (AD) is not clear, in particular in the…”
Get full text

CSF β-amyloid and white matter damage: a new perspective on Alzheimer’s disease by Pietroboni, Anna M, Scarioni, Marta, Carandini, Tiziana, Basilico, Paola, Cadioli, Marcello, Giulietti, Giovanni, Arighi, Andrea, Caprioli, Michela, Serra, Laura, Sina, Clara, Fenoglio, Chiara, Ghezzi, Laura, Fumagalli, Giorgio G, De Riz, Milena A, Calvi, Alberto, Triulzi, Fabio, Bozzali, Marco, Scarpini, Elio, Galimberti, Daniela

“…ObjectiveTo assess the connection between amyloid pathology and white matter (WM) macrostructural and microstructural damage in demented patients compared with…”
Get full text

Caregiver Tele-Assistance for Reduction of Emotional Distress During the COVID-19 Pandemic. Psychological Support to Caregivers of People with Dementia: The Italian Experience by Rotondo, Emanuela, Galimberti, Daniela, Mercurio, Matteo, Giardinieri, Giulia, Forti, Sara, Vimercati, Roberto, Borracci, Vittoria, Fumagalli, Giorgio G, Pietroboni, Anna M, Carandini, Tiziana, Nobili, Alessandro, Scarpini, Elio, Arighi, Andrea

“…COVID-19 pandemic worsened vulnerability of patients with dementia (PWD). This new reality associated with government restriction and isolation worsened stress…”
Get more information

Quantitative susceptibility mapping of the normal-appearing white matter as a potential new marker of disability progression in multiple sclerosis by Pietroboni, Anna M., Colombi, Annalisa, Contarino, Valeria E., Russo, Francesco Maria Lo, Conte, Giorgio, Morabito, Aurelia, Siggillino, Silvia, Carandini, Tiziana, Fenoglio, Chiara, Arighi, Andrea, De Riz, Milena A., Arcaro, Marina, Sacchi, Luca, Fumagalli, Giorgio G., Bianchi, Anna Maria, Triulzi, Fabio, Scarpini, Elio, Galimberti, Daniela

“…Objectives To investigate the normal-appearing white matter (NAWM) susceptibility in a cohort of newly diagnosed multiple sclerosis (MS) patients and to…”
Get full text

Predominant right temporal lobe atrophy: Clinical, neuropsychological and structural differences based on amyloid status by Di Napoli, Jacopo, Arighi, Andrea, Conte, Giorgio, Carandini, Tiziana, Sacchi, Luca, Arcaro, Marina, Fenoglio, Chiara, Sorrentino, Federica, Mercurio, Matteo, Pietroboni, Anna M., Giardinieri, Giulia, Triulzi, Fabio, Galimberti, Daniela, Scarpini, Elio, Fumagalli, Giorgio G.

“…Background Predominant right temporal atrophy is a radiological sign usually associated with frontotemporal dementia but this sign can also be present in…”
Get full text

The loss of macular ganglion cells begins from the early stages of disease and correlates with brain atrophy in multiple sclerosis patients by Pietroboni, Anna M, Dell’Arti, Laura, Caprioli, Michela, Scarioni, Marta, Carandini, Tiziana, Arighi, Andrea, Ghezzi, Laura, Fumagalli, Giorgio G, De Riz, Milena A, Basilico, Paola, Colombi, Annalisa, Benatti, Eleonora, Triulzi, Fabio, Scarpini, Elio, Viola, Francesco, Galimberti, Daniela

“…Background: The importance of neurodegeneration in multiple sclerosis (MS) is increasingly well recognized. Objectives: To evaluate retinal pathology using…”
Get full text

Niemann-Pick Type C 1 (NPC1) and NPC2 Gene Variability in Demented Patients with Evidence of Brain Amyloid Deposition by Sorrentino, Federica, Arighi, Andrea, Serpente, Maria, Arosio, Beatrice, Arcaro, Marina, Visconte, Caterina, Rotondo, Emanuela, Vimercati, Roberto, Ferri, Evelyn, Fumagalli, Giorgio G, Pietroboni, Anna M, Carandini, Tiziana, Scarpini, Elio, Fenoglio, Chiara, Galimberti, Daniela

“…Variants in Niemann-Pick Type C genes (NPC1 and NPC2) have been suggested to play a role as risk or disease modifying factors for Alzheimer's disease (AD). The…”
Get more information

Amyloid PET as a marker of normal-appearing white matter early damage in multiple sclerosis: correlation with CSF β-amyloid levels and brain volumes by Pietroboni, Anna M., Carandini, Tiziana, Colombi, Annalisa, Mercurio, Matteo, Ghezzi, Laura, Giulietti, Giovanni, Scarioni, Marta, Arighi, Andrea, Fenoglio, Chiara, De Riz, Milena A., Fumagalli, Giorgio G., Basilico, Paola, Serpente, Maria, Bozzali, Marco, Scarpini, Elio, Galimberti, Daniela, Marotta, Giorgio

“…Purpose The disease course of multiple sclerosis (MS) is unpredictable, and reliable prognostic biomarkers are needed. Positron emission tomography (PET) with…”
Get full text

Diencephalic versus Hippocampal Amnesia in Alzheimer's Disease: The Possible Confabulation-Misidentification Phenotype by Abbate, Carlo, Trimarchi, Pietro D, Fumagalli, Giorgio G, Gallucci, Alessia, Tomasini, Emanuele, Fracchia, Stefania, Rebecchi, Isabella, Morello, Elisabetta, Fontanella, Anna, Parisi, Paola M R, Tartarone, Federica, Giunco, Fabrizio, Ciccone, Simona, Nicolini, Paola, Lucchi, Tiziano, Arosio, Beatrice, Inglese, Silvia, Rossi, Paolo D

“…Alzheimer's disease (AD) is clinically heterogeneous, including the classical-amnesic (CA-) phenotype and some variants. We aim to describe a further…”
Get more information

Evidence of CNS β-amyloid deposition in Nasu-Hakola disease due to the TREM2 Q33X mutation by Ghezzi, Laura, Carandini, Tiziana, Arighi, Andrea, Fenoglio, Chiara, Arcaro, Marina, De Riz, Milena, Pietroboni, Anna M, Fumagalli, Giorgio G, Basilico, Paola, Calvi, Alberto, Scarioni, Marta, Colombi, Annalisa, Serpente, Maria, Marotta, Giorgio, Benti, Riccardo, Scarpini, Elio, Galimberti, Daniela

Get full text

CSF β-amyloid predicts prognosis in patients with multiple sclerosis by Pietroboni, Anna M, Caprioli, Michela, Carandini, Tiziana, Scarioni, Marta, Ghezzi, Laura, Arighi, Andrea, Cioffi, Sara, Cinnante, Claudia, Fenoglio, Chiara, Oldoni, Emanuela, De Riz, Milena A, Basilico, Paola, Fumagalli, Giorgio G, Colombi, Annalisa, Giulietti, Giovanni, Serra, Laura, Triulzi, Fabio, Bozzali, Marco, Scarpini, Elio, Galimberti, Daniela

“…Background: The importance of predicting disease progression in multiple sclerosis (MS) has increasingly been recognized, and hence reliable biomarkers are…”
Get full text