Search Results - "Fults, D W"
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The Life of Rudolf Nissen: Advancing Surgery Through Science and Principle
Published in World journal of surgery (01-06-2011)“…Rudolf Nissen (1896–1981) was a surgeon whose career began in Germany during the first third of the 20th century, a period of rapid progress in biomedical…”
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2
Sporadic medulloblastomas contain PTCH mutations
Published in Cancer research (Chicago, Ill.) (01-03-1997)“…Nevoid basal cell carcinoma syndrome (NBCCS), or Gorlin's syndrome, is an autosomal dominant disorder that predisposes to developmental defects and various…”
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3
Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice
Published in Oncogene (12-08-2004)“…Medulloblastoma (MB) is a malignant brain tumor that arises in the cerebellum of children. Activation of the Sonic hedgehog/Patched (Shh/Ptc) signaling pathway…”
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4
pp60c-src in the developing cerebellum
Published in Molecular and Cellular Biology (01-01-1985)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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c-Myc Enhances Sonic Hedgehog-Induced Medulloblastoma Formation from Nestin-Expressing Neural Progenitors in Mice
Published in Neoplasia (New York, N.Y.) (01-05-2003)“…Medulloblastomas are malignant brain tumors that arise in the cerebella of children. The presumed cellsof-origin are undifferentiated precursors of granule…”
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6
Astrocytoma and pineoblastoma arising sequentially in the fourth ventricle of the same patient. Case report and molecular analysis
Published in Pediatric neurosurgery (01-01-1997)“…The sequential appearance of two different brain tumors in the same patient without intervening radiation or chemotherapy is a rare event, most often seen in…”
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7
Rig is a Novel Ras-Related Protein and Potential Neural Tumor Suppressor
Published in Proceedings of the National Academy of Sciences - PNAS (23-07-2002)“…The Ras superfamily consists of a large group of monomeric GTPases demonstrating homology to Ras oncoproteins. Although structurally similar, Ras-superfamily…”
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8
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort
Published in The lancet oncology (01-06-2018)“…Medulloblastoma is associated with rare hereditary cancer predisposition syndromes; however, consensus medulloblastoma predisposition genes have not been…”
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9
An early developmental phase of pp60c-src expression in the neural ectoderm
Published in Developmental biology (01-09-1986)“…The expression of the normal cellular src protein (pp60c-src) was investigated in the early chick embryo during gastrulation and neurulation by…”
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10
rek, a Gene Expressed in Retina and Brain, Encodes a Receptor Tyrosine Kinase of the Axl/Tyro3 Family
Published in The Journal of biological chemistry (15-11-1996)“…Rek (retina-expressed kinase) has been identified as a putative novel receptor-type tyrosine kinase of the Axl/Tyro3 family with a potential role in neural…”
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11
Loss of heterozygosity on chromosome 10 in human glioblastoma multiforme
Published in Genomics (San Diego, Calif.) (1989)“…Recessive mutations, revealed by loss of the wild-type allele, have been associated with the development of a variety of cancers in children and adults…”
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12
Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and medulloblastomas
Published in Cancer research (Chicago, Ill.) (01-08-2004)“…The phosphatidylinositol 3'-kinase pathway is activated in multiple advanced cancers, including glioblastomas, through inactivation of the PTEN tumor…”
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13
MYC Expression Promotes the Proliferation of Neural Progenitor Cells in Culture and In Vivo
Published in Neoplasia (New York, N.Y.) (01-01-2002)“…Primitive neuroectodermal tumors. (20PNETs) are pediatric brain tumors that result from defects in signaling molecules governing the growth and differentiation…”
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14
EPENDYMOMA
Published in Neuro-oncology (Charlottesville, Va.) (01-06-2012)Get full text
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PEDIATRICS LABORATORY RESEARCH
Published in Neuro-oncology (Charlottesville, Va.) (01-11-2011)Get full text
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Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid
Published in Cancer research (Chicago, Ill.) (01-02-2005)“…Through digital karyotyping of permanent medulloblastoma cell lines, we found that the homeobox gene OTX2 was amplified more than 10-fold in three cell lines…”
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Molecular, genetic, and cellular pathogenesis of neurofibromas and surgical implications
Published in Neurosurgery (01-01-2006)“…Neurofibromatosis 1 (NF1) is a common autosomal dominant disease characterized by complex and multicellular neurofibroma tumors. Significant advances have been…”
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18
c-src and other proto-oncogenes implicated in neuronal differentiation
Published in Molecular and chemical neuropathology (01-02-1989)“…The proto-oncogene c-src has been implicated in the development and mature function of the nervous system. pp60c-src, the protein product of the c-src gene, is…”
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Spontaneous hemorrhage associated with a pilomyxoid astrocytoma: Case report
Published in Journal of neurosurgery (01-08-2003)“…Pilomyxoid astrocytomas have been identified as a more aggressive variant of pilocytic astrocytomas that occur in infants and in young children. These tumors…”
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pp60 super(c-src) in the developing cerebellum
Published in Molecular and cellular biology (01-01-1985)“…pp60 super(c-src) was localized in the cerebellum of developing chicken embryos by immunoperoxidase staining with antisera raised against bacterially expressed…”
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