Search Results - "Fuller, David"
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Pattern sensitivity of ampakine-hypoxia interactions for evoking phrenic motor facilitation in anesthetized rat
Published in Journal of neurophysiology (01-02-2024)“…Repeated hypoxic episodes can produce a sustained (>60 min) increase in neural drive to the diaphragm. The requirement of repeated hypoxic episodes (vs. a…”
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2
Ampakines increase diaphragm activation following mid-cervical contusion injury in rats
Published in Experimental neurology (01-06-2024)“…Ampakines are positive allosteric modulators of AMPA receptors. We hypothesized that low-dose ampakine treatment increases diaphragm electromyogram (EMG)…”
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3
Respiratory neuroplasticity – Overview, significance and future directions
Published in Experimental neurology (01-01-2017)“…Neuroplasticity is an important property of the neural system controlling breathing. However, our appreciation for its importance is still relatively new, and…”
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4
Ampakines Stimulate Diaphragm Activity after Spinal Cord Injury
Published in Journal of neurotrauma (15-12-2021)“…Respiratory compromise after cervical spinal cord injury (SCI) is a leading cause of mortality and morbidity. Most SCIs are incomplete, and spinal respiratory…”
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5
Osteopathic Approach to the Treatment of a Patient With Idiopathic Iliohypogastric Neuralgia
Published in The Journal of the American Osteopathic Association (01-12-2020)“…Iliohypogastric neuralgia is an uncommon etiology of lower abdominal pain caused by entrapment of the iliohypogastric nerve. Conventional management consists…”
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6
Alternative models for markets with nonconvexities
Published in European journal of operational research (01-09-2017)“…•Near equilibrium market models when firms have discrete variables.•Extending minimum uplift to allow price-sensitive, non-dispatchable demand.•Minimum…”
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Ampakine pretreatment enables a single hypoxic episode to produce phrenic motor facilitation with no added benefit of additional episodes
Published in Journal of neurophysiology (01-10-2021)“…Repeated short episodes of hypoxia produce a sustained increase in phrenic nerve output lasting well beyond acute intermittent hypoxia (AIH) exposure (i.e.,…”
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8
Targeting drug or gene delivery to the phrenic motoneuron pool
Published in Journal of neurophysiology (01-01-2023)“…Phrenic motoneurons (PhrMNs) innervate diaphragm myofibers. Located in the ventral gray matter (lamina IX), PhrMNs form a column extending from approximately…”
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Intermittent hypoxia and neurorehabilitation
Published in Journal of applied physiology (1985) (15-12-2015)“…In recent years, it has become clear that brief, repeated presentations of hypoxia [i.e., acute intermittent hypoxia (AIH)] can boost the efficacy of more…”
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10
Automated Classification of Whole Body Plethysmography Waveforms to Quantify Breathing Patterns
Published in Frontiers in physiology (20-08-2021)“…Whole body plethysmography (WBP) monitors respiratory rate and depth but conventional analysis fails to capture the diversity of waveforms. Our first purpose…”
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11
Characterizing the structural rearrangement of the bacterial nucleoid by Dps
Published in Biophysical journal (10-02-2023)Get full text
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12
Revealing the accessibility and surface morphology of the Escherichia coli nucleoid by genetically encoded live-cell single-particle tracking
Published in Biophysical journal (10-02-2023)Get full text
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13
The respiratory neuromuscular system in Pompe disease
Published in Respiratory physiology & neurobiology (01-11-2013)“…Highlights • Pompe disease occurs due to mutations in the gene encoding the lysosomal enzyme acid α-glucosidase (GAA). • Respiratory insufficiency and tongue…”
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14
An analysis of differential gene expression in peripheral nerve and muscle utilizing RNA sequencing after polyethylene glycol nerve fusion in a rat sciatic nerve injury model
Published in PloS one (04-09-2024)“…Application of polyethylene glycol (PEG) to a peripheral nerve injury at the time of primary neurorrhaphy is thought to prevent Wallerian degeneration via…”
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15
Autonomous control of ventilation through closed-loop adaptive respiratory pacing
Published in Scientific reports (14-12-2020)“…Mechanical ventilation is the standard treatment when volitional breathing is insufficient, but drawbacks include muscle atrophy, alveolar damage, and reduced…”
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More Information on Osteopathic Manipulative Medicine Consultations for Hospitalized Patients
Published in The Journal of the American Osteopathic Association (01-04-2020)Get full text
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17
Prolonged diaphragm activation using closed loop optogenetic stimulation
Published in The FASEB journal (01-05-2022)“…Diaphragm dysfunction in individuals with late stage neuromuscular disease and cervical spinal cord injury is a substantial problem, often resulting in…”
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18
Ampakine‐Hypoxia Induced Phrenic Motor Facilitation is Not Prevented by Intrathecal Methysergide
Published in The FASEB journal (01-05-2022)“…Hypoxia‐induced sustained increases in phrenic nerve burst amplitude lasting beyond the hypoxic stimulus are generally accepted to require repeated bouts of…”
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19
The Pattern of Ampakine and Hypoxia Exposure Determines Phrenic Motor Facilitation
Published in The FASEB journal (01-05-2022)“…Phrenic motor facilitation (pMF) is a persistent increase in phrenic nerve activity upon the removal of a triggering stimuli. A variety of stimulation…”
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20
Split Thickness Skin Graft to Lower Leg
Published in Journal of orthopaedic trauma (01-08-2016)“…The purpose of this video is to demonstrate the steps of harvesting, meshing, and applying a split thickness skin graft (STSG) to a lower leg to cover a…”
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