Search Results - "Fukuzawa, Akiko"

Pharmacological profile of semotiadil fumarate, a novel calcium antagonist, in rat experimental angina model by Mori, Tomohiro, Ishigai, Yutaka, Fukuzawa, Akiko, Chiba, Kiyoshi, Shibano, Toshiro

“…1 The aim of the present study was to determine whether antianginal efficacy of semotiadil fumarate (SD‐3211), a structurally novel calcium antagonist, is…”
Get full text

Rational Design and Evaluation of New Lead Compound Structures for Selective βARK1 Inhibitors by Iino, Minoru, Furugori, Taketoshi, Mori, Tomohiro, Moriyama, Sachiko, Fukuzawa, Akiko, Shibano, Toshiro

“…β-Adrenergic receptor kinase 1 (βARK1) and cyclic adenosine 5‘-monophosphate-dependent protein kinase A (PKA) have structurally similar adenine-binding pockets…”
Get full text

Role of bradykinin-NO pathway in prevention of cardiac hypertrophy by ACE inhibitor in rat cardiomyocytes by Ishigai, Y, Mori, T, Ikeda, T, Fukuzawa, A, Shibano, T

“…To examine whether the bradykinin-nitric oxide (NO) pathway directly participates in the antihypertrophic property of angiotensin-converting enzyme (ACE)…”
Get full text

Evaluation of high trough-to-peak ratio of perindopril in SHR by Moriyama, Sachiko, Ishigai, Yutaka, Mori, Tomohiro, Fukuzawa, Akiko, Shibano, Toshiro

“…The trough-to-peak ratio (T/P) has been a clinically useful parameter to assess the effectiveness of antihypertentive drugs over the dose interval. However,…”
Get full text

Involvement of reduction of PAI-1 in beneficial effects of perindopril on prevention of stroke by Morivama, Sachiko, Ishigai, Yutaka, Mori, Tomohiro, Fukuzawa, Akiko, Shibano, Toshiro, Kubo, Hideo

“…Plasma plasminogen activator inhibitor-1 (PAI-1) would participate in coronary thrombotic process in patients with myocardial infarction. However, the role of…”
Get full text

Blockade of the slow component of the delayed rectifier potassium currents by carvedilol in Xenopus oocytes by Ishigai, Yutaka, Mori, Tomohiro, Moriyama, Sachiko, Fukuzawa, Akiko, Shibano, Toshiro, Kubo, Hideo

“…In the present study, we examined whether carvedilol, α_1 and β blocker, affects slow component of I_K (I_Ks ) channels expressed in Xenopus oocytes. cRNAs…”
Get full text

Carvedilol improved survival rate without affecting blood pressure in Dahl salt-sensitive rats by Mori, Tomohiro, Ishigai, Yutaka, Moriyama, Sachiko, Furugohri, Taketoshi, Fukuzawa, Akiko, Shibano, Toshiro

“…Dahl salt-sensitive (DS) rat has recently been demonstrated as a unique model for heart failure. In the present study, we examined the effects of carvedilol,…”
Get full text

Rational design and evaluation of new lead compound structures for selective betaARK1 inhibitors by Iino, Minoru, Furugori, Taketoshi, Mori, Tomohiro, Moriyama, Sachiko, Fukuzawa, Akiko, Shibano, Toshiro

“…Beta-adrenergic receptor kinase 1 (betaARK1) and cyclic adenosine 5'-monophosphate-dependent protein kinase A (PKA) have structurally similar adenine-binding…”
Get full text

Asp278 of Human β-Adrenergic Receptor Kinase 1 Is Essential for Phosphorylation Activity by Iino, Minoru, Furugohri, Taketoshi, Fukuzawa, Akiko, Shibano, Toshiro

“…Asp278 of β-adrenergic receptor kinase 1 (βARK1) was suggested to play a key role in substrate recognition of β2-adrenergic receptors in our previous study, in…”
Get full text

Role of bradykinin-no pathway in prevention of cardiac hypertrophy by ace inhibitor by Ishigai, Yutaka, Mori, Tomohiro, Ikeda, Toshiko, Furugohri, Taketoshi, Fukuzawa, Akiko, Shibano, Toshiro

Get full text

Carvedilol improved survival rate in dahl salt-sensitive rats as a model for heart failure by Mori, Tomohiro, Ishigai, Yutaka, Moriyama, Sachiko, Furugohri, Taketoshi, Fukuzawa, Akiko, Shibano, Toshiro

Get full text

Evaluation of High Trough-to-Peak Ratio of Perindopril in Shr by Moriyama, Sachiko, Ishigai, Yutaka, Mori, Tomohiro, Fukuzawa, Akiko, Shibano, Toshiro

Get full text

Lack of correlation of hypotensive effects with prevention of cardiac hypertrophy by perindopril after ligation of rat coronary artery by Chiba, Kiyoshi, Moriyama, Sachiko, Ishigai, Yutaka, Fukuzawa, Akiko, Irie, Kiyoshi, Shibano, Toshiro

“…1 The present study was designed to test the hypothesis that beneficial effects of angiotensin converting enzyme (ACE)inhibitors are independent of a fall in…”
Get full text

P-309 - Involvement of bradykinin-NO pathway in the antihypertrophic effects of perindoprilat in the rat neonatal cardiac myocytes by Ishigai, Yutaka, Mori, Tomohiro, Fukuzawa, Akiko, Shibano, Toshiro

Get full text

Involvement of bradykinin-NO pathway in the antihypertrophic effects of perindoprilat in the rat neonatal cardiac myocytes by Ishigai, Yutaka, Mori, Tomohiro, Fukuzawa, Akiko, Shibano, Toshiro

Get full text

O-146 - Involvement of reduction of PAI-1 in beneficial effects of perindopril on prevention of stroke by Morivama, Sachiko, Ishigai, Yutaka, Mori, Tomohiro, Fukuzawa, Akiko, Shibano, Toshiro, Kubo, Hideo

Get full text

O-222 - Blockade of the slow component of the delayed rectifier potassium currents by carvedilol in Xenopus oocytes by Ishigai, Yutaka, Mori, Tomohiro, Moriyama, Sachiko, Fukuzawa, Akiko, Shibano, Toshiro, Kubo, Hideo

Get full text

Effects of perindopril on tissue angiotensin- converting enzyme activity in rats with myocardial infarction by Moriyama, Sachiko, Chiba, Kiyoshi, Ishisai, Yutaka, Fukuzawa, Akiko, Irie, Kiyoshi, Watanabe, Yoshifumi, Ashida, Shinichiro

Get full text

P-121 - Effects of perindopril on tissue angiotensin- converting enzyme activity in rats with myocardial infarction by Moriyama, Sachiko, Chiba, Kiyoshi, Ishisai, Yutaka, Fukuzawa, Akiko, Irie, Kiyoshi, Watanabe, Yoshifumi, Ashida, Shinichiro

Get full text

P-215 - Perindopril, a novel angiotensin-converting enzyme inhibitor, restores diminished endothelium-mediated vasodilation in rats with myocardial infarction by Ishigai, Yutaka, Chiba, Kiyoshi, Moriyama, Sachiko, Fukuzawa, Akiko, Irie, Kiyoshi, Watanabe, Yoshifumi, Ashida, Shinichiro

Get full text