Search Results - "Fukushi, Abekura"
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Revisited Metabolic Control and Reprogramming Cancers by Means of the Warburg Effect in Tumor Cells
Published in International journal of molecular sciences (02-09-2022)“…Aerobic glycolysis is an emerging hallmark of many human cancers, as cancer cells are defined as a “metabolically abnormal system”. Carbohydrates are…”
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GM1a ganglioside-binding domain peptide inhibits host adhesion and inflammatory response of enterotoxigenic Escherichia coli heat-labile enterotoxin-B in HCT-8 cells
Published in Scientific reports (06-10-2023)“…Enterotoxigenic Escherichia coli (ETEC) is a major cause of illness and death but has no effective therapy. The heat-labile enterotoxin LT is a significant…”
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Mycobacterium tuberculosis glycolipoprotein LprG inhibits inflammation through NF‐κB signaling of ERK1/2 and JNK in LPS‐induced murine macrophage cells
Published in Journal of cellular biochemistry (01-04-2022)“…Mycobacterium tuberoculosis (Mtb) is a contagious pathogen that causes human tuberculosis (TB). TB is a major global health threat that causes 9.6 million…”
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Naturally-Occurring Tyrosinase Inhibitors Classified by Enzyme Kinetics and Copper Chelation
Published in International journal of molecular sciences (05-05-2023)“…Currently, there are three major assaying methods used to validate in vitro whitening activity from natural products: methods using mushroom tyrosinase, human…”
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Up‐regulation of inflammatory reactions by MPT32, a secreted protein of Mycobacterium tuberculosis in RAW264.7 macrophages
Published in Journal of cellular biochemistry (01-09-2023)“…Tuberculosis (TB) is caused by Mycobacterium tuberculosis (Mtb) and is still one of the global health burdens. The occurrence of various cases and multidrug…”
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3′-sialyllactose targets cell surface protein, SIGLEC-3, and induces megakaryocyte differentiation and apoptosis by lipid raft-dependent endocytosis
Published in Glycoconjugate journal (01-04-2020)“…3′-sialyllactose is one of the abundant components in human milk oligosaccharides (HMOs) that protect infants from various viral infections in early stages of…”
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Esculentoside H inhibits colon cancer cell migration and growth through suppression of MMP‐9 gene expression via NF‐kB signaling pathway
Published in Journal of cellular biochemistry (01-06-2019)“…A water‐soluble saponin, Esculentoside H (EsH), 3‐O‐(O‐β‐d‐glucopyranosyl‐(1→4)‐β‐d‐xylopyranosyl)‐28‐β‐d‐glucopyranosylphytolaccagenin has been isolated and…”
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Transcriptional Activation of Human GD3 Synthase (hST8Sia I) Gene in Curcumin-Induced Autophagy in A549 Human Lung Carcinoma Cells
Published in International journal of molecular sciences (02-07-2018)“…Curcumin, a natural polyphenolic compound isolated from the plant , is known to induce autophagy in various cancer cells, including lung cancer. In the present…”
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Oldenlandia diffusa suppresses metastatic potential through inhibiting matrix metalloproteinase-9 and intercellular adhesion molecule-1 expression via p38 and ERK1/2 MAPK pathways and induces apoptosis in human breast cancer MCF-7 cells
Published in Journal of ethnopharmacology (04-01-2017)“…Oldenlandia diffusa (OD) has long been known as an apoptotic inducer in breast tumors in ethnomedicine. To scientifically confirm the anti-breast cancer…”
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Regulation of human β-galactoside α2,6-sialyltransferase (hST6Gal I) gene expression during differentiation of human osteoblastic MG-63 cells
Published in Glycoconjugate journal (01-12-2020)“…In this study, we found that gene expression of the human β-galactoside α2,6-sialyltransferase (hST6Gal I) was specifically increased during differentiation of…”
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4‐O‐carboxymethylascochlorin protected against microglial‐mediated neurotoxicity in SH‐SY5Y and BV2 cocultured cells from LPS–induced neuroinflammation and death by inhibiting MAPK, NF‐κB, and Akt pathways
Published in Journal of cellular biochemistry (01-02-2019)“…In our previous studies, structurally similar compounds of ascochlorin and ascofuranone exhibited anti‐inflammatory activity. Neural inflammation plays a…”
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Avenanthramide C Suppresses Matrix Metalloproteinase-9 Expression and Migration Through the MAPK/NF- κB Signaling Pathway in TNF-α-Activated HASMC Cells
Published in Frontiers in pharmacology (25-03-2021)“…In oat ingredients, flavonoids and phenolic acids are known to be the most important phenolic compounds. In phenolic compounds, wide-ranging biological…”
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Ganglioside GM3 suppresses lipopolysaccharide‐induced inflammatory responses in rAW 264.7 macrophage cells through NF‐κB, AP‐1, and MAPKs signaling
Published in Journal of cellular biochemistry (01-01-2018)“…Gangliosides are known to specifically inhibit vascular leukocyte recruitment and consequent interaction with the injured endothelium, the basic inflammatory…”
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Mycobacterium tuberculosis–Secreted Protein, ESAT-6, Inhibits Lipopolysaccharide-Induced MMP-9 Expression and Inflammation Through NF-κB and MAPK Signaling in RAW 264.7 Macrophage Cells
Published in Inflammation (01-02-2020)“…-20pt?> Mycobacterium tuberculosis (Mtb) is a pathogenic bacterium that causes contagious tuberculosis (TB). Recently, Mtb-secreted proteins have been…”
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4- O -Carboxymethylascochlorin Inhibits Expression Levels of on Inflammation-Related Cytokines and Matrix Metalloproteinase-9 Through NF-κB/MAPK/TLR4 Signaling Pathway in LPS-Activated RAW264.7 Cells
Published in Frontiers in pharmacology (27-03-2019)“…Toll-like receptor 4 (TLR4) and matrix metalloproteinase-9 (MMP-9) are known to play important roles in inflammatory diseases such as arteriosclerosis and…”
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Exogenous and Endogeneous Disialosyl Ganglioside GD1b Induces Apoptosis of MCF-7 Human Breast Cancer Cells
Published in International journal of molecular sciences (30-04-2016)“…Gangliosides have been known to play a role in the regulation of apoptosis in cancer cells. This study has employed disialyl-ganglioside GD1b to apoptosis in…”
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Ascofuranone inhibits lipopolysaccharide-induced inflammatory response via NF-kappaB and AP-1, p-ERK, TNF-α, IL-6 and IL-1β in RAW 264.7 macrophages
Published in PloS one (2017)“…The natural fungal compound ascofuranone…”
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Jellyfish extract induces apoptotic cell death through the p38 pathway and cell cycle arrest in chronic myelogenous leukemia K562 cells
Published in PeerJ (San Francisco, CA) (19-01-2017)“…Jellyfish species are widely distributed in the world's oceans, and their population is rapidly increasing. Jellyfish extracts have several biological…”
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Sialyllactose suppresses angiogenesis by inhibiting VEGFR-2 activation, and tumor progression
Published in Oncotarget (29-08-2017)Get full text
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A novel Mycobacterium Tuberculosis antigen, MTB48 enhances inflammatory response in LPS-induced RAW264.7 macrophage immune cells
Published in Molecular immunology (01-02-2024)“…Mtb (Mycobacterium tuberculosis) is a pathogenic bacterium that causes tuberculosis infection (TB). Mtb-secreted proteins have recently been investigated as…”
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