Search Results - "Fukumura, Masayuki"
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A Staphylococcus pro-apoptotic peptide induces acute exacerbation of pulmonary fibrosis
Published in Nature communications (24-03-2020)“…Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal disease of unknown etiology; however, apoptosis of lung alveolar epithelial cells plays a role in…”
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2
Inhibition of lung microbiota-derived proapoptotic peptides ameliorates acute exacerbation of pulmonary fibrosis
Published in Nature communications (23-03-2022)“…Idiopathic pulmonary fibrosis is an incurable disease of unknown etiology. Acute exacerbation of idiopathic pulmonary fibrosis is associated with high…”
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3
Nucleocytoplasmic shuttling of the human parainfluenza virus type 2 phosphoprotein
Published in Virology (New York, N.Y.) (01-02-2019)“…Human parainfluenza virus type 2 phosphoprotein (P) is an essential component of viral polymerase. The P gene encodes both P and accessory V proteins by a…”
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4
A versatile platform technology for recombinant vaccines using non-propagative human parainfluenza virus type 2 vector
Published in Scientific reports (09-09-2019)“…Ectopic protein with proper steric structure was efficiently loaded onto the envelope of the F gene-defective BC-PIV vector derived from human parainfluenza…”
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5
Non-propagative human parainfluenza virus type 2 nasal vaccine robustly protects the upper and lower airways against SARS-CoV-2
Published in iScience (17-12-2021)“…We developed an intranasal vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using the replication-incompetent human parainfluenza…”
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6
A Cytoplasmic RNA Vector Derived from Nontransmissible Sendai Virus with Efficient Gene Transfer and Expression
Published in Journal of Virology (01-07-2000)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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7
Next Generation RNA/Protein‐Carrying Vector With Pleiotropic Activity
Published in Reviews in medical virology (01-11-2024)“…ABSTRACT Human parainfluenza virus type 2 (hPIV2), one of the causative agents of infantile common cold, is a non‐segmented negative‐sense RNA virus with a…”
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8
Rescue of ischemic brain injury by adenoviral gene transfer of glial cell line-derived neurotrophic factor after transient global ischemia in gerbils
Published in Brain research (08-12-2000)“…Glial cell line-derived neurotrophic factor (GDNF), a member of the transforming growth factor (TGF)–β superfamily, is one of the most potent neurotrophic…”
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9
Sendai Virus Vector-mediated Gene Transfer of Glial Cell Line-Derived Neurotrophic Factor Prevents Delayed Neuronal Death after Transient Global Ischemia in Gerbils
Published in Experimental Animals (01-04-2003)“…We have developed a cytoplasmic replicating virus vector of Sendai virus (SeV) that infects and replicates in most mammalian cells, including neurons, and…”
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10
Cloning, sequencing, and expression of the gene encoding the Clostridium stercorarium xylanase C in Escherichia coli
Published in Bioscience, biotechnology, and biochemistry (01-09-1999)“…The nucleotide sequence of the Clostridium stercorarium F-9 xynC gene, encoding a xylanase XynC, consists of 3,093 bp and encodes a 1,031-amino acids with a…”
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11
The Nasal Epithelium as a Factory for Systemic Protein Delivery
Published in Molecular therapy (01-02-2002)“…We have previously shown that recombinant Sendai virus (SeV) produces efficient in vivo airway epithelial gene transfer. The ability to produce therapeutic…”
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Abstract 3253: Novel gene & protein-carrying vector BC-PIV expressing immunomodulatory molecules potently stimulates anti-tumor immunity against solid tumors in mice
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Background: Cancer immunotherapy such as immune-checkpoint inhibitors or CAR-T cell therapy has emerged as an effective therapeutic modality for some…”
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13
Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma
Published in Cancer Letters (18-07-2003)“…Neuroblastoma (NBL) is a common pediatric cancer originated from the neuronal precursor cells of sympathoadrenal lineage. NBLs show a variety of clinical…”
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Book Review Journal Article -
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Nucleotide Sequence of the Clostridium stercorarium xynB Gene Encoding an Extremely Thermostable Xylanase, and Characterization of the Translated Product
Published in Bioscience, biotechnology, and biochemistry (01-01-1995)“…The nucleotides of the xynB gene of Clostridium stercorarium F-9 were sequenced. The structural gene consists of an open reading frame of 1161 bp encoding a…”
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15
Human parainfluenza virus type 2 vector induces dendritic cell maturation without viral RNA replication/transcription
Published in Human gene therapy (01-07-2013)“…The dendritic cell (DC), a most potent antigen-presenting cell, plays a key role in vaccine therapy against infectious diseases and malignant tumors. Although…”
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16
Process of Thermal Denaturation of Xylanase (XynB) from Clostridium stercorarium F-9
Published in Bioscience, biotechnology, and biochemistry (01-01-1995)“…The thermal denaturation process of Clostridium stercorarium F-9 xylanase (XynB) was studied by monitoring remaining activity and recovered activity of the…”
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17
Recombinant Sendai virus‐mediated gene transfer to vasculature: a new class of efficient gene transfer vector to the vascular system
Published in The FASEB journal (01-05-2001)Get full text
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Efficient gene transfer to airway epithelium using recombinant Sendai virus
Published in Nature biotechnology (01-09-2000)“…Clinical studies of gene therapy for cystic fibrosis (CF) suggest that the key problem is the efficiency of gene transfer to the airway epithelium. The…”
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19
Accommodation of foreign genes into the Sendai virus genome: sizes of inserted genes and viral replication
Published in FEBS letters (06-08-1999)“…Sendai virus (SeV) is an enveloped virus with a negative sense genome RNA of about 15.3 kb. We previously established a system to recover an infectious virus…”
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Recombinant Sendai virus‐mediated gene transfer to vasculature: a new class of efficient gene transfer vector to the vascular system
Published in The FASEB journal (01-05-2001)“…ABSTRACT Unsolved issues in clinical gene therapy for cardiovascular diseases include gene transfer efficiency and the requirement of a longer exposure time…”
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