Search Results - "Fukui, Yamato"
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Uterine receptivity, embryo attachment, and embryo invasion: Multistep processes in embryo implantation
Published in Reproductive medicine and biology (01-07-2019)“…Background Recurrent implantation failure is a critical issue in IVF‐ET treatment. Successful embryo implantation needs appropriate molecular and cellular…”
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Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations
Published in Nature communications (19-12-2019)“…Uterine adenomyosis is a benign disorder that often co-occurs with endometriosis and/or leiomyoma, and impairs quality of life. The genomic features of…”
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Constant Activation of STAT3 Contributes to the Development of Adenomyosis in Females
Published in Endocrinology (Philadelphia) (01-05-2022)“…Adenomyosis is a benign uterine disease that causes dysmenorrhea, heavy menstrual bleeding, and infertility; however, its pathophysiology remains unclear…”
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Uterine Epithelial Progesterone Receptor Governs Uterine Receptivity Through Epithelial Cell Differentiation
Published in Endocrinology (Philadelphia) (01-12-2020)“…Progesterone receptor (PGR) is indispensable for pregnancy in mammals. Uterine PGR responds to the heightened levels of ovarian progesterone (P4) after…”
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Uterine Epithelial LIF Receptors Contribute to Implantation Chamber Formation in Blastocyst Attachment
Published in Endocrinology (Philadelphia) (01-11-2021)“…Recent studies have demonstrated that the formation of an implantation chamber composed of a uterine crypt, an implantation-competent blastocyst, and uterine…”
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CD206+ M2-Like Macrophages Are Essential for Successful Implantation
Published in Frontiers in immunology (23-10-2020)“…Macrophages (MΦs) play important roles in implantation. Depletion of CD11b+ pan-MΦs in CD11b-diphtheria-toxin-receptor (DTR) mice is reported to cause…”
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Differential roles of uterine epithelial and stromal STAT3 coordinate uterine receptivity and embryo attachment
Published in Scientific reports (23-09-2020)“…Although it has been reported that uterine signal transducer and activator of transcription 3 (STAT3) is essential for embryo implantation, the exact roles of…”
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DNA Methylation and Histone Modification Are the Possible Regulators of Preimplantation Blastocyst Activation in Mice
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-02-2023)“…Under ovarian hormone control, dormant blastocysts obtain implantation capacity (known as blastocyst activation) through their global gene expression. After…”
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Retinoblastoma protein promotes uterine epithelial cell cycle arrest and necroptosis for embryo invasion
Published in EMBO reports (03-02-2021)“…Retinoblastoma protein (RB) encoded by Rb1 is a prominent inducer of cell cycle arrest (CCA). The hormone progesterone (P 4 ) promotes CCA in the uterine…”
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Levonorgestrel Inhibits Embryo Attachment by Eliminating Uterine Induction of Leukemia Inhibitory Factor
Published in Endocrinology (Philadelphia) (01-02-2020)“…Abstract Progestogens including progesterone (P4) and levonorgestrel (LNG) are clinically used for multiple purposes such as contraception and infertility…”
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The EZH2–PRC2–H3K27me3 axis governs the endometrial cell cycle and differentiation for blastocyst invasion
Published in Cell death & disease (18-05-2023)“…Infertility occurs in 15% of couples worldwide. Recurrent implantation failure (RIF) is one of the major problems in in vitro fertilization and embryo transfer…”
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A gene network of uterine luminal epithelium organizes mouse blastocyst implantation
Published in Reproductive medicine and biology (01-01-2022)“…Purpose The receptive endometrium is critical for blastocyst implantation. In mice, after blastocysts enter the uterine cavities on day 4 of pregnancy (day…”
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Uterine Receptivity is Reflected by LIF Expression in the Cervix
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-05-2022)“…Recurrent implantation failure is a major problem in assisted reproductive technology (ART). Although ART systems have evolved rapidly over the decades, it is…”
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Pregnancy is associated with reduced progression of symptomatic adenomyosis: a retrospective pilot study
Published in BMC pregnancy and childbirth (04-09-2023)“…Abstract Background Adenomyosis is a common gynecological disease in women of reproductive age and causes various symptoms such as dysmenorrhea and heavy…”
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Multi-physics simulation of oxygen diffusion in PSZ–Ti composites during spark plasma sintering process
Published in Computational materials science (01-12-2014)“…[Display omitted] •Fabrication of PSZ–Ti composite for implant material.•Multi-physics simulation of spark plasma sintering by finite element…”
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KRAS mutations in uterine endometrium are associated with gravidity and parity
Published in Cell death & disease (11-05-2020)Get full text
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Blood Vessel Invasion Is a Strong Predictor of Postoperative Recurrence in Endometrial Cancer
Published in International journal of gynecological cancer (01-06-2018)“…Although lymphovascular space invasion is a prognostic factor for the recurrence of resectable endometrial cancer, the differential impacts of lymphatic vessel…”
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Levonorgestrel-Releasing Intrauterine System Improves Menorrhagia-Related Quality of Life in Patients with Symptomatic Adenomyosis
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-03-2023)“…Levonorgestrel-releasing intrauterine system (LNG-IUS) relieves dysmenorrhea and heavy menstrual bleeding (HMB) in adenomyosis. However, its efficacy on…”
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Spatiotemporally distinct roles of cyclooxygenase-1 and cyclooxygenase-2 at fetomaternal interface in mice
Published in JCI insight (27-08-2024)“…Embryo implantation is crucial for ensuring a successful pregnancy outcome and subsequent child health. The intrauterine environment during the…”
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