Search Results - "Fukue, Yoshihiko"
-
1
Ghrelin Directly Regulates Bone Formation
Published in Journal of bone and mineral research (01-05-2005)“…To clarify the role of ghrelin in bone metabolism, we examined the effect of ghrelin in vitro and in vivo. Ghrelin and its receptor, GHS‐R1a, were identified…”
Get full text
Journal Article -
2
Ingested Medium-Chain Fatty Acids Are Directly Utilized for the Acyl Modification of Ghrelin
Published in Endocrinology (Philadelphia) (01-05-2005)“…Ghrelin, an acylated brain and gut peptide, is primarily produced by endocrine cells of the gastric mucosa for secretion into the circulation. The major active…”
Get full text
Journal Article -
3
Molecular Forms of Hypothalamic Ghrelin and Its Regulation by Fasting and 2-Deoxy-d-Glucose Administration
Published in Endocrinology (Philadelphia) (01-06-2005)“…Ghrelin, an endogenous ligand for the GH secretagogue receptor, is a hormone expressed in stomach and other tissues, such as hypothalamus, testis, and…”
Get full text
Journal Article -
4
Dysfunction of muscarinic acetylcholine receptors as a substantial basis for progressive neurological deterioration in GM3-only mice
Published in Behavioural brain research (05-01-2010)“…To examine the effects of deletion of gangliosides on the nervous system by avoiding masking effects with the remaining structures, we established double…”
Get full text
Journal Article -
5
Regulation of gonadotropin secretion and puberty onset by neuromedin U
Published in FEBS letters (12-06-2006)“…Neuromedin U (NMU), an anorexigenic peptide, was originally isolated from porcine spinal cord in 1985. As NMU is abundant in the anterior pituitary gland, we…”
Get full text
Journal Article -
6
Disruption of the Prepulse Inhibition of the Startle Reflex in Vasopressin V1b Receptor Knockout Mice: Reversal by Antipsychotic Drugs
Published in Neuropsychopharmacology (New York, N.Y.) (01-11-2005)“…In the present study, we investigated whether mice lacking the arginine vasopressin (AVP) V1b receptor (V1bR) exhibit deficits of prepulse inhibition (PPI) of…”
Get full text
Journal Article -
7
V1a receptor knockout mice exhibit impairment of spatial memory in an eight-arm radial maze
Published in Neuroscience letters (19-02-2004)“…In this study, we examined the performance of vasopressin V1a receptor (V1aR) and vasopressin V1b receptor (V1bR) knockout (KO) mice compared to wild-type (WT)…”
Get full text
Journal Article -
8
Characteristics of behavioral abnormalities in α1d-adrenoceptors deficient mice
Published in Behavioural brain research (01-07-2004)Get full text
Journal Article -
9
The Pharmacological Characterization of Attentional Processes Using a Two-lever Choice Reaction Time Task in Rats
Published in Biological & pharmaceutical bulletin (01-12-2002)“…Activating the noradrenergic and cholinergic systems is known to enhance attentional processes, while stimulating dopaminergic, serotonergic, and GABAergic…”
Get full text
Journal Article -
10
Ghrelin deficiency does not influence feeding performance
Published in Regulatory peptides (10-01-2008)“…Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor that is synthesized predominantly in the stomach. Previous studies demonstrated…”
Get full text
Journal Article Conference Proceeding -
11
Reduced motor and sensory functions and emotional response in GM3-only mice: Emergence from early stage of life and exacerbation with aging
Published in Behavioural brain research (02-03-2009)“…Sialic acid-containing glycosphingolipids (gangliosides) have been believed to play a role in the regulation and protection of nervous tissues. To clarify…”
Get full text
Journal Article -
12
Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway
Published in Nature medicine (01-10-2004)“…Neuromedin U (NMU) is a hypothalamic neuropeptide that regulates body weight and composition. Here we show that mice lacking the gene encoding NMU (Nmu(-/-)…”
Get full text
Journal Article -
13
Characteristics of behavioral abnormalities in alpha1d-adrenoceptors deficient mice
Published in Behavioural brain research (09-07-2004)“…To investigate the functional role of alpha1d-adrenergic receptor (alpha1d-AR) in the CNS, we have generated mutant mice lacking the alpha1d-AR using a gene…”
Get full text
Journal Article -
14
-
15
Characteristics of behavioral abnormalities in α 1d-adrenoceptors deficient mice
Published in Behavioural brain research (2004)“…To investigate the functional role of α 1d-adrenergic receptor (α 1d-AR) in the CNS, we have generated mutant mice lacking the α 1d-AR using a gene targeting…”
Get full text
Journal Article