Search Results - "Fukudome, Eugene Y."
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Identification of citrullinated histone H3 as a potential serum protein biomarker in a lethal model of lipopolysaccharide-induced shock
Published in Surgery (01-09-2011)“…Background Circulating proteins may serve as biomarkers for the early diagnosis and treatment of shock. We have recently demonstrated that treatment with…”
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Journal Article -
2
Surviving blood loss without blood transfusion in a swine poly-trauma model
Published in Surgery (01-08-2009)“…Background We have demonstrated previously that valproic acid (VPA), a histone deacetylase inhibitor, can improve survival in lethal models of hemorrhagic…”
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Journal Article -
3
National perioperative outcomes of flap coverage for pressure ulcers from 2005 to 2015 using American College of Surgeons National Surgical Quality Improvement Program
Published in Archives of plastic surgery (01-09-2018)“…Complication rates after flap coverage for pressure ulcers have been high historically. These patients have multiple risk factors associated with poor wound…”
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Journal Article -
4
Pharmacologic resuscitation decreases circulating cytokine-induced neutrophil chemoattractant-1 levels and attenuates hemorrhage-induced acute lung injury
Published in Surgery (01-08-2012)“…Background Acute lung injury (ALI) is a complication of hemorrhagic shock (HS). Histone deacetylase inhibitors, such as valproic acid (VPA), can improve…”
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Journal Article -
5
Protective effect of suberoylanilide hydroxamic acid against LPS-induced septic shock in rodents
Published in Shock (Augusta, Ga.) (01-11-2009)“…We have recently found that suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor, improves survival in a lethal model of hemorrhagic shock…”
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Journal Article -
6
Surviving lethal septic shock without fluid resuscitation in a rodent model
Published in Surgery (01-08-2010)“…Background We have recently demonstrated that treatment with suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor, before a lethal dose of…”
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Journal Article Conference Proceeding -
7
Histone Deacetylase Inhibitor Treatment Attenuates MAP Kinase Pathway Activation and Pulmonary Inflammation Following Hemorrhagic Shock in a Rodent Model
Published in The Journal of surgical research (01-07-2012)“…Background Hemorrhagic shock activates cellular stress signals and can lead to systemic inflammatory response, organ injury, and death. We have previously…”
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Journal Article -
8
Surgical outcomes of sternal rigid plate fixation from 2005 to 2016 using the American College of Surgeons-National Surgical Quality Improvement Program database
Published in Archives of plastic surgery (01-07-2019)“…Sternal rigid plate fixation (RPF) has been adopted in recent years in high-risk cases to reduce complications associated with steel wire cerclage, the…”
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Journal Article -
9
Histone deacetylase inhibitor suberoylanilide hydroxamic acid attenuates Toll-like receptor 4 signaling in lipopolysaccharide-stimulated mouse macrophages
Published in The Journal of surgical research (01-12-2012)“…Abstract Objective We have previously demonstrated that pretreatment and posttreatment of animals with suberoylanilide hydroxamic acid (SAHA), a histone…”
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Journal Article -
10
Creating a “pro-survival” phenotype through epigenetic modulation
Published in Surgery (01-09-2012)“…Background We demonstrated recently that treatment with suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor, improved survival in a rodent…”
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Journal Article -
11
Pharmacologic Resuscitation Promotes Survival and Attenuates Hemorrhage-Induced Activation of Extracellular Signal-Regulated Kinase 1/2
Published in The Journal of surgical research (01-09-2010)“…Background Hemorrhage is the leading cause of preventable trauma-related deaths, and histone deacetylase inhibitors (HDACI) such as valproic acid (VPA) can…”
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Journal Article Conference Proceeding -
12
Identification of a Novel Potential Biomarker in a Model of Hemorrhagic Shock and Valproic Acid Treatment
Published in The Journal of surgical research (01-03-2010)“…Background The initial management of a poly-trauma patient requires evaluation for potential hemorrhage and ongoing monitoring to assess the efficacy of…”
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Journal Article -
13
The Current State of Surgical Ergonomics Education in U.S. Surgical Training: A Survey Study
Published in Annals of surgery (01-04-2019)“…OBJECTIVE:The aim of this study was to characterize the current state of surgical ergonomics education in the United States. BACKGROUND:The burden of…”
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Journal Article -
14
National perioperative outcomes of flap coverage for pressure ulcers from 2005 to 2015 using American College of Surgeons National Surgical Quality Improvement Program
Published in Archives of plastic surgery (2018)“…Background Complication rates after flap coverage for pressure ulcers have been high historically. These patients have multiple risk factors associated with…”
Get full text
Journal Article -
15
Surgical outcomes of sternal rigid plate fixation from 2005 to 2016 using the American College of Surgeons-National Surgical Quality Improvement Program database
Published in Archives of plastic surgery (2019)“…Background Sternal rigid plate fixation (RPF) has been adopted in recent years in high-risk cases to reduce complications associated with steel wire cerclage,…”
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Journal Article -
16
Outpatient Prosthetic-Based Reconstruction during COVID-19 Pandemic Possible in Selected Patients without Increased Complications
Published in Plastic and reconstructive surgery (1963) (01-06-2023)“…Following the reopening of elective surgery, the authors' division transitioned from inpatient admission to same-day discharge for immediate prosthetic breast…”
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Journal Article -
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Surgical management of hidradenitis suppurativa: procedural trends and risk factors
Published in The Journal of surgical research (01-09-2018)“…Hidradenitis suppurativa (HS) is a chronic debilitating cutaneous disorder. The recalcitrant nature of this disease may require surgery in severe cases. We…”
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Journal Article -
18
Referrals of Plastic Surgery Patients to Integrative Medicine Centers: A Review of Resource Utility
Published in Annals of plastic surgery (01-07-2019)“…BACKGROUNDIntegrative medicine (IM) centers are becoming more established nationwide and provide an expansive range of therapeutic services. Given the high…”
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Journal Article -
19
Integrative Medicine in Plastic Surgery: A Systematic Review of Our Literature
Published in Annals of plastic surgery (01-04-2019)“…BACKGROUNDSurveys have reported that as high as 80% of plastic surgery patients utilize integrative medicine approaches including natural products (NPs) and…”
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Journal Article -
20
Topical nitroglycerin for the treatment of intraoperative microsurgical vasospasm
Published in Microsurgery (01-07-2018)“…Background Papaverine remains a popular agent to treat intraoperative microsurgical vasospasm. However, the recent shortage has forced surgeons to trial…”
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