Search Results - "Fukuda, Michiko"
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Development of an orally-administrable tumor vasculature-targeting therapeutic using annexin A1-binding D-peptides
Published in PloS one (06-01-2021)“…We previously reported that IF7 peptide, which binds to the annexin A1 (ANXA1) N-terminus, functions as a tumor vasculature-targeted drug delivery vehicle…”
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Sentential inference bridging between lexical/grammatical knowledge and text comprehension among native Chinese speakers learning Japanese
Published in PloS one (13-04-2023)“…The current study explored the role of sentential inference in connecting lexical/grammatical knowledge and overall text comprehension in foreign language…”
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The transcription factor ATF2 promotes melanoma metastasis by suppressing protein fucosylation
Published in Science signaling (08-12-2015)“…Melanoma is one of the most lethal skin cancers worldwide, primarily because of its propensity to metastasize. Thus, the elucidation of mechanisms that govern…”
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Annexin A1 expression is correlated with malignant potential of renal cell carcinoma
Published in International journal of urology (01-02-2019)“…Objectives To evaluate the expression of annexin A1 protein in patients with renal cell carcinoma. Methods Annexin A1 expression was examined in renal cell…”
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Essential role of gastric gland mucin in preventing gastric cancer in mice
Published in The Journal of clinical investigation (01-03-2012)“…Gastric gland mucin secreted from the lower portion of the gastric mucosa contains unique O-linked oligosaccharides (O-glycans) having terminal α1,4-linked…”
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Tumor suppressor function of laminin-binding alpha -dystroglycan requires a distinct beta 3-N- acetylglucosaminyltransferase
Published in Proceedings of the National Academy of Sciences - PNAS (21-07-2009)“…alpha -Dystroglycan ( alpha -DG) represents a highly glycosylated cell surface molecule that is expressed in the epithelial cell-basement membrane (BM)…”
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Tumor suppressor function of laminin-binding α-dystroglycan requires a distinct β3-N-acetylglucosaminyltransferase
Published in Proceedings of the National Academy of Sciences - PNAS (21-07-2009)“…α-Dystroglycan (α-DG) represents a highly glycosylated cell surface molecule that is expressed in the epithelial cell-basement membrane (BM) interface and…”
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Vaccination inhibits the human adenoviral transduction in a mouse keratoconjunctivitis model
Published in Vaccine (11-06-2021)“…Adenovirus infections are a major cause of epidemic keratoconjunctivitis (EKC), which can lead to corneal subepithelial infiltrates and multifocal corneal…”
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Targeted drug delivery to tumor vasculature by a carbohydrate mimetic peptide
Published in Proceedings of the National Academy of Sciences - PNAS (06-12-2011)“…Although numerous carbohydrates play significant roles in mammalian cells, carbohydrate-based drug discovery has not been explored due to the technical…”
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Correction to: Tumor vasculature-targeted 10B delivery by an Annexin A1-binding peptide boosts effects of boron neutron capture therapy
Published in BMC cancer (29-01-2021)“…An amendment to this paper has been published and can be accessed via the original article…”
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Tumor vasculature-targeted 10B delivery by an Annexin A1-binding peptide boosts effects of boron neutron capture therapy
Published in BMC cancer (15-01-2021)“…Abstract Background p -Boronophenylalanine ( 10 BPA) is a powerful 10 B drug used in current clinical trials of BNCT. For BNCT to be successful, a high (500…”
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Overcoming the blood–brain barrier by Annexin A1-binding peptide to target brain tumours
Published in British journal of cancer (24-11-2020)“…Background Annexin A1 is expressed specifically on the tumour vasculature surface. Intravenously injected IF7 targets tumour vasculature via annexin A1. We…”
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Determination of Carbohydrate Structure Recognized by Prostate-specific F77 Monoclonal Antibody through Expression Analysis of Glycosyltransferase Genes
Published in The Journal of biological chemistry (06-06-2014)“…This study reports the determination of the carbohydrate epitope of monoclonal antibody F77 previously raised against human prostate cancer PC-3 cells (Zhang,…”
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Carbohydrate Sequence of the Prostate Cancer-associated Antigen F77 Assigned by a Mucin O-Glycome Designer Array
Published in The Journal of biological chemistry (06-06-2014)“…Monoclonal antibody F77 was previously raised against human prostate cancer cells and has been shown to recognize a carbohydrate antigen, but the carbohydrate…”
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Analysis of A4gnt Knockout Mice Reveals an Essential Role for Gastric Sulfomucins in Preventing Gastritis Cystica Profunda
Published in The journal of histochemistry and cytochemistry (01-10-2019)“…Gastric adenocarcinoma cells secrete sulfomucins, but their role in gastric tumorigenesis remains unclear. To address that question, we generated A4gnt/Chst4…”
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Overexpression of Zinc‐Finger Protein 777 (ZNF777) Inhibits Proliferation at Low Cell Density Through Down‐Regulation of FAM129A
Published in Journal of cellular biochemistry (01-06-2015)“…ABSTRACT Krüppel‐associated box‐containing zinc finger proteins (KRAB‐ZFPs) regulate a wide range of cellular processes. KRAB‐ZFPs have a KRAB domain, which…”
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Peptide-displaying phage technology in glycobiology
Published in Glycobiology (Oxford) (01-03-2012)“…Phage display technology is an emerging drug discovery tool. Using that approach, short peptides that mimic part of a carbohydrate's conformation are selected…”
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Natural Antibiotic Function of a Human Gastric Mucin against Helicobacter pylori Infection
Published in Science (American Association for the Advancement of Science) (13-08-2004)“…Helicobacter pylori infects the stomachs of nearly a half the human population, yet most infected individuals remain asymptomatic, which suggests that there is…”
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Core3 O-Glycan Synthase Suppresses Tumor Formation and Metastasis of Prostate Carcinoma PC3 and LNCaP Cells through Down-regulation of α2β1 Integrin Complex
Published in The Journal of biological chemistry (19-06-2009)“…Although there are numerous reports of carbohydrates enriched in cancer cells, very few studies have addressed the functions of carbohydrates present in normal…”
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Carbohydrate Mimetic Peptides as Research Reagent and Therapeutic
Published in Biological & pharmaceutical bulletin (01-10-2012)“…Although numerous carbohydrates play significant roles in mammalian cells, development of carbohydrate-based reagents and therapeutics are hampered by the…”
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