Search Results - "Fukuda, Hokuto"

Attenuation of Post‐Traumatic Osteoarthritis After Anterior Cruciate Ligament Injury Via Inhibition of Hedgehog Signaling by Takada, Shinichiro, Nakamura, Eiichiro, Sabanai, Ken, Tsukamoto, Manabu, Otomo, Hajime, Kanoh, Shinkichi, Murai, Teppei, Fukuda, Hokuto, Okada, Yasuaki, Uchida, Soshi, Sakai, Akinori

“…ABSTRACT We aimed to investigate whether post‐traumatic osteoarthritis (PTOA) progression is appropriately represented by a PTOA mouse model using a unique…”
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Chronic obstructive pulmonary disease severity in middle-aged and older men with osteoporosis associates with decreased bone formation by Tsukamoto, Manabu, Mori, Toshiharu, Nakamura, Eiichiro, Okada, Yasuaki, Fukuda, Hokuto, Yamanaka, Yoshiaki, Sabanai, Ken, Wang, Ke-Yong, Hanagiri, Takeshi, Kuboi, Satoshi, Yatera, Kazuhiro, Sakai, Akinori

“…Chronic obstructive pulmonary disease (COPD) is a risk factor for osteoporosis. Nevertheless, much remains unclear regarding the bone metabolism dynamics…”
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Systemic bone loss, impaired osteogenic activity and type I muscle fiber atrophy in mice with elastase-induced pulmonary emphysema: Establishment of a COPD-related osteoporosis mouse model by Tsukamoto, Manabu, Mori, Toshiharu, Wang, Ke-Yong, Okada, Yasuaki, Fukuda, Hokuto, Naito, Keisuke, Yamanaka, Yoshiaki, Sabanai, Ken, Nakamura, Eiichiro, Yatera, Kazuhiro, Sakai, Akinori

“…Although it is suggested that chronic obstructive pulmonary disease (COPD) and bone are related, almost all of the pathological mechanisms of COPD-related…”
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Disruption of the aldehyde dehydrogenase 2 gene increases the bone anabolic response to intermittent PTH treatment in an ovariectomized mouse model by Kosugi, Kenji, Tajima, Takafumi, Menuki, Kunitaka, Okuma, Kayoko Furukawa, Tokuda, Kotaro, Fukuda, Hokuto, Okada, Yasuaki, Tsukamoto, Manabu, Yamanaka, Yoshiaki, Zenke, Yukichi, Sakai, Akinori

“…Aldehyde dehydrogenase 2 (ALDH2) is the enzyme that oxidizes the acetaldehyde produced by alcohol metabolism. This variant not only affects the response to…”
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Cortical bone loss due to skeletal unloading in aldehyde dehydrogenase 2 gene knockout mice is associated with decreased PTH receptor expression in osteocytes by Tajima, Takafumi, Menuki, Kunitaka, Okuma, Kayoko Furukawa, Tsukamoto, Manabu, Fukuda, Hokuto, Okada, Yasuaki, Kosugi, Kenji, Yamanaka, Yoshiaki, Uchida, Soshi, Sakai, Akinori

“…Aldehyde dehydrogenase 2 (ALDH2) is the enzyme that degrades and detoxifies the acetaldehyde produced by alcohol metabolism. In our previous study, we found…”
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Disruption of the Aldehyde Dehydrogenase 2 Gene Results in No Increase in Trabecular Bone Mass Due to Skeletal Loading in Association with Impaired Cell Cycle Regulation Through p21 Expression in the Bone Marrow Cells of Mice by Okuma, Kayoko Furukawa, Menuki, Kunitaka, Tsukamoto, Manabu, Tajima, Takafumi, Fukuda, Hokuto, Okada, Yasuaki, Mori, Toshiharu, Tsuchiya, Takuto, Kawamoto, Toshihiro, Yoshida, Yasuhiro, Uchida, Soshi, Sakai, Akinori

“…Approximately 45% of people of East Asian descent have the inactive aldehyde dehydrogenase 2 (ALDH2) phenotype. The enzyme defect of ALDH2 has been found to…”
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