Search Results - "Fuki, Ilia"

Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo by Wang, Xun, Collins, Heidi L, Ranalletta, Mollie, Fuki, Ilia V, Billheimer, Jeffrey T, Rothblat, George H, Tall, Alan R, Rader, Daniel J

“…Macrophage ATP-binding cassette transporter A1 (ABCA1), scavenger receptor class B type I (SR-BI), and ABCG1 have been shown to promote cholesterol efflux to…”
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Lecithin: Cholesterol Acyltransferase Expression Has Minimal Effects on Macrophage Reverse Cholesterol Transport In Vivo by TANIGAWA, Hiroyuki, BILLHEIMER, Jeffrey T, TOHYAMA, Jun-Ichiro, FUKI, Ilia V, NG, Dominic S, ROTHBLAT, George H, RADER, Daniel J

“…Lecithin:cholesterol acyltransferase (LCAT) catalyzes the formation of plasma cholesteryl ester, plays a key role in high-density lipoprotein metabolism, and…”
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Overexpression of Apolipoprotein F Reduces HDL Cholesterol Levels In Vivo by Lagor, William R., Brown, Robert J., Toh, Sue-Anne, Millar, John S., Fuki, Ilia V., de la Llera-Moya, Margarita, Yuen, Tiffany, Rothblat, George, Billheimer, Jeffrey T., Rader, Daniel J.

“…Apolipoprotein F (ApoF) is a protein component of several lipoprotein classes including HDL. It is also known as lipid transfer inhibitor protein (LTIP) based…”
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Pathways by Which Reconstituted High-Density Lipoprotein Mobilizes Free Cholesterol From Whole Body and From Macrophages by Cuchel, Marina, Lund-Katz, Sissel, de la Llera-Moya, Margarita, Millar, John S, Chang, David, Fuki, Ilia, Rothblat, George H, Phillips, Michael C, Rader, Daniel J

“…OBJECTIVE—Reconstituted high-density lipoprotein (rHDL) is of interest as a potential novel therapy for atherosclerosis because of its ability to promote free…”
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Adipocyte Enhancer-Binding Protein 1 Is a Potential Novel Atherogenic Factor Involved in Macrophage Cholesterol Homeostasis and Inflammation by Majdalawieh, Amin, Zhang, Lei, Fuki, Ilia V., Rader, Daniel J., Ro, Hyo-Sung

“…Peroxisome proliferator-activated receptor γl (PPARγl) and liver X receptor α (LXRα) play pivotal roles in macrophage cholesterol homeostasis and inflammation,…”
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Endogenously Produced Endothelial Lipase Enhances Binding and Cellular Processing of Plasma Lipoproteins via Heparan Sulfate Proteoglycan-mediated Pathway by Fuki, Ilia V., Blanchard, Nadine, Jin, Weijun, Marchadier, Dawn H.L., Millar, John S., Glick, Jane M., Rader, Daniel J.

“…Endothelial lipase (EL) is a new member of the triglyceride lipase gene family, which includes lipoprotein lipase (LpL) and hepatic lipase (HL). Enzymatic…”
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A naturally occurring variant of endothelial lipase associated with elevated HDL exhibits impaired synthesis[S] by Brown, Robert J., Edmondson, Andrew C., Griffon, Nathalie, Hill, Theophelus B., Fuki, Ilia V., Badellino, Karen O., Li, Mingyao, Wolfe, Megan L., Reilly, Muredach P., Rader, Daniel J.

“…Human endothelial lipase (EL) is a member of a family of lipases and phospholipases that are involved in the metabolism of plasma lipoproteins. EL displays a…”
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Potent and Selective PPAR-α Agonist LY518674 Upregulates Both ApoA-I Production and Catabolism in Human Subjects With the Metabolic Syndrome by Millar, John S., Duffy, Danielle, Gadi, Ramprasad, Bloedon, LeAnne T., Dunbar, Richard L., Wolfe, Megan L., Movva, Rajesh, Shah, Ashish, Fuki, Ilia V., McCoy, Mary, Harris, Cynthia J., Wang, Ming-Dauh, Howey, Daniel C., Rader, Daniel J.

“…The study of PPAR-alpha activation on apoA-I production in humans has been limited to fibrates, relatively weak PPAR-alpha agonists that may have other…”
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Effects of nevirapine and efavirenz on HDL cholesterol levels and reverse cholesterol transport in mice by Tohyama, Junichiro, Billheimer, Jeffrey T, Fuki, Ilia V, Rothblat, George H, Rader, Daniel J, Millar, John S

“…Abstract Objective The mechanism by which non-nucleoside reverse transcriptase inhibitors (NNRTIs) increase HDL cholesterol (HDL-C) in HIV+ patients and the…”
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Endothelial Lipase Promotes the Catabolism of ApoB-Containing Lipoproteins by Broedl, Uli C, Maugeais, Cyrille, Millar, John S, Jin, Weijun, Moore, Ryan E, Fuki, Ilia V, Marchadier, Dawn, Glick, Jane M, Rader, Daniel J

“…Endothelial lipase (EL) has been found to be a key enzyme in high-density lipoprotein (HDL) metabolism in mice, leading to the concept that inhibition of EL…”
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Endothelial lipase is less effective at influencing HDL metabolism in vivo in mice expressing apoA-II by Broedl, Uli C., Jin, Weijun, Fuki, Ilia V., Millar, John S., Rader, Daniel J.

“…Endothelial lipase (EL) plays an important physiological role in modulating HDL metabolism. Data suggest that plasma contains an inhibitor of EL, and previous…”
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Proprotein Covertases Are Responsible for Proteolysis and Inactivation of Endothelial Lipase by Jin, Weijun, Fuki, Ilia V., Seidah, Nabil G., Benjannet, Suzanne, Glick, Jane M., Rader, Daniel J.

“…Plasma lipoprotein metabolism is tightly regulated by several members of the triglyceride lipase family, including endothelial lipase (EL) and lipoprotein…”
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Role of N-linked glycosylation in the secretion and activity of endothelial lipase by Miller, Gwen C., Long, Christopher J., Bojilova, Ekaterina D., Marchadier, Dawn, Badellino, Karen O., Blanchard, Nadine, Fuki, Ilia V., Glick, Jane M., Rader, Daniel J.

“…Human endothelial lipase (EL), a member of the triglyceride lipase gene family, has five potential N-linked glycosylation sites, two of which are conserved in…”
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Normal Production Rate of Apolipoprotein B in LDL Receptor–Deficient Mice by Millar, John S, Maugeais, Cyrille, Fuki, Ilia V, Rader, Daniel J

“…The low density lipoprotein (LDL) receptor is well known for its role in mediating the removal of apolipoprotein B (apoB)-containing lipoproteins from plasma…”
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Structural basis of endothelial lipase tropism for HDL by Broedl, Uli C., Jin, Weijun, Fuki, Ilia V., Glick, Jane M., Rader, Daniel J.

“…Lipoprotein lipase (LPL) and endothelial lipase (EL), the most closely related enzymes among the members of the triglyceride lipase gene family with regard to…”
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Transmembrane and cytoplasmic domains of syndecan mediate a multi-step endocytic pathway involving detergent-insoluble membrane rafts by FUKI, Ilia V., MEYER, Marie E., WILLIAMS, Kevin Jon

“…Syndecan heparan sulphate proteoglycans directly mediate a novel endocytic pathway. Using Chinese hamster ovary cells expressing the human syndecan 1 core…”
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Perlecan Heparan Sulfate Proteoglycan by Fuki, Ilia V., Iozzo, Renato V., Williams, Kevin Jon

“…Cell surface heparan sulfate proteoglycans (HSPGs) participate in the catabolism of many physiologically important ligands. We previously reported that…”
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PPARγ activation redirects macrophage cholesterol from fecal excretion to adipose tissue uptake in mice via SR-BI by Toh, Sue-Anne, Millar, John S., Billheimer, Jeffrey, Fuki, Ilia, Naik, Snehal U., Macphee, Colin, Walker, Max, Rader, Daniel J.

“…PPARγ agonists, used in the treatment of Type 2 diabetes, can raise HDL-cholesterol, therefore could potentially stimulate macrophage-to-feces reverse…”
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Both the Peroxisome Proliferator-Activated Receptor δ Agonist, GW0742, and Ezetimibe Promote Reverse Cholesterol Transport in Mice by Reducing Intestinal Reabsorption of HDL-Derived Cholesterol by Briand, François, Naik, Snehal U., Fuki, Ilia, Millar, John S., Macphee, Colin, Walker, Max, Billheimer, Jeffrey, Rothblat, George, Rader, Daniel J.

“…Peroxisome proliferator‐activated receptor δ (PPARδ) agonism increases HDL cholesterol and has therefore the potential to stimulate macrophage‐to‐feces reverse…”
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Transmembrane and cytoplasmic domains of syndecan mediate a multi-step endocytic pathway involving detergent-insoluble membrane rafts by Fuki, I V, Meyer, M E, Williams, K J

“…Syndecan heparan sulphate proteoglycans directly mediate a novel endocytic pathway. Using Chinese hamster ovary cells expressing the human syndecan 1 core…”
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