Search Results - "Fukazawa, Yugo"

Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers by Lanjakornsiripan, Darin, Pior, Baek-Jun, Kawaguchi, Daichi, Furutachi, Shohei, Tahara, Tomoaki, Katsuyama, Yu, Suzuki, Yutaka, Fukazawa, Yugo, Gotoh, Yukiko

“…Non-pial neocortical astrocytes have historically been thought to comprise largely a nondiverse population of protoplasmic astrocytes. Here we show that…”
Get full text

Region‐ and neuronal‐subtype‐specific expression of Na,K‐ATPase alpha and beta subunit isoforms in the mouse brain by Murata, Koshi, Kinoshita, Tomoki, Ishikawa, Tatsuya, Kuroda, Kazuki, Hoshi, Minako, Fukazawa, Yugo

“…Na,K‐ATPase is a ubiquitous molecule contributing to the asymmetrical distribution of Na+ and K+ ions across the plasma membrane and maintenance of the…”
Get full text

Optogenetic Control of Synaptic AMPA Receptor Endocytosis Reveals Roles of LTD in Motor Learning by Kakegawa, Wataru, Katoh, Akira, Narumi, Sakae, Miura, Eriko, Motohashi, Junko, Takahashi, Akiyo, Kohda, Kazuhisa, Fukazawa, Yugo, Yuzaki, Michisuke, Matsuda, Shinji

“…Long-term depression (LTD) of AMPA-type glutamate receptor (AMPA receptor)-mediated synaptic transmission has been proposed as a cellular substrate for…”
Get full text

Occludin and tricellulin facilitate formation of anastomosing tight-junction strand network to improve barrier function by Saito, Akira C, Higashi, Tomohito, Fukazawa, Yugo, Otani, Tetsuhisa, Tauchi, Masashi, Higashi, Atsuko Y, Furuse, Mikio, Chiba, Hideki

“…Tight junctions (TJs) are composed of a claudin-based anastomosing network of TJ strands at which plasma membranes of adjacent epithelial cells are closely…”
Get full text

Optogenetic countering of glial acidosis suppresses glial glutamate release and ischemic brain damage by Beppu, Kaoru, Sasaki, Takuya, Tanaka, Kenji F, Yamanaka, Akihiro, Fukazawa, Yugo, Shigemoto, Ryuichi, Matsui, Ko

“…The brain demands high-energy supply and obstruction of blood flow causes rapid deterioration of the healthiness of brain cells. Two major events occur upon…”
Get full text

Tight junction formation by a claudin mutant lacking the COOH‐terminal PDZ domain‐binding motif by Fujiwara, Sachiko, Nguyen, Thanh Phuong, Furuse, Kyoko, Fukazawa, Yugo, Otani, Tetsuhisa, Furuse, Mikio

“…Claudin‐based tight junctions (TJs) are formed at the most apical part of cell–cell contacts in epithelial cells. Previous studies suggest that scaffolding…”
Get full text

EpCAM proteolysis and release of complexed claudin-7 repair and maintain the tight junction barrier by Higashi, Tomohito, Saito, Akira C, Fukazawa, Yugo, Furuse, Mikio, Higashi, Atsuko Y, Ono, Masahiro, Chiba, Hideki

“…TJs maintain the epithelial barrier by regulating paracellular permeability. Since TJs are under dynamically fluctuating intercellular tension, cells must…”
Get full text

Effects of TAMP family on the tight junction strand network and barrier function in epithelial cells by Saito, Akira C., Endo, Chisato, Fukazawa, Yugo, Higashi, Tomohito, Chiba, Hideki

“…Occludin, tricellulin, and marvelD3 belong to the tight junction (TJ)‐associated MARVEL protein family. Occludin and tricellulin jointly contribute to TJ…”
Get full text

Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain by Kim, Sun Kwang, Hayashi, Hideaki, Ishikawa, Tatsuya, Shibata, Keisuke, Shigetomi, Eiji, Shinozaki, Youichi, Inada, Hiroyuki, Roh, Seung Eon, Kim, Sang Jeong, Lee, Gihyun, Bae, Hyunsu, Moorhouse, Andrew J, Mikoshiba, Katsuhiko, Fukazawa, Yugo, Koizumi, Schuichi, Nabekura, Junichi

“…Long-term treatments to ameliorate peripheral neuropathic pain that includes mechanical allodynia are limited. While glial activation and altered nociceptive…”
Get full text

Reconstitution of functional tight junctions with individual claudin subtypes in epithelial cells by Furuse, Mikio, Nakatsu, Daiki, Hempstock, Wendy, Sugioka, Shiori, Ishizuka, Noriko, Furuse, Kyoko, Sugawara, Taichi, Fukazawa, Yugo, Hayashi, Hisayoshi

“…The claudin family of membrane proteins is responsible for the backbone structure and function of tight junctions (TJs), which regulate the paracellular…”
Get full text

Transient astrocytic mGluR5 expression drives synaptic plasticity and subsequent chronic pain in mice by Danjo, Yosuke, Shigetomi, Eiji, Hirayama, Yukiho J, Kobayashi, Kenji, Ishikawa, Tatsuya, Fukazawa, Yugo, Shibata, Keisuke, Takanashi, Kenta, Parajuli, Bijay, Shinozaki, Youichi, Kim, Sun Kwang, Nabekura, Junichi, Koizumi, Schuichi

“…Activation of astrocytes has a profound effect on brain plasticity and is critical for the pathophysiology of several neurological disorders including…”
Get full text

Application of an optogenetic byway for perturbing neuronal activity via glial photostimulation by Sasaki, Takuya, Beppu, Kaoru, Tanaka, Kenji F, Fukazawa, Yugo, Shigemoto, Ryuichi, Matsui, Ko

“…Dynamic activity of glia has repeatedly been demonstrated, but if such activity is independent from neuronal activity, glia would not have any role in the…”
Get full text

Endogenous opioids in the olfactory tubercle and their roles in olfaction and quality of life by Murata, Koshi, Maegawa, Ayako, Imoto, Yoshimasa, Fujieda, Shigeharu, Fukazawa, Yugo

“…Olfactory dysfunctions decrease daily quality of life (QOL) in part by reducing the pleasure of eating. Olfaction plays an essential role in flavor sensation…”
Get full text

Synaptic pruning through glial synapse engulfment upon motor learning by Morizawa, Yosuke M., Matsumoto, Mami, Nakashima, Yuka, Endo, Narumi, Aida, Tomomi, Ishikane, Hiroshi, Beppu, Kaoru, Moritoh, Satoru, Inada, Hitoshi, Osumi, Noriko, Shigetomi, Eiji, Koizumi, Schuichi, Yang, Guang, Hirai, Hirokazu, Tanaka, Kohichi, Tanaka, Kenji F., Ohno, Nobuhiko, Fukazawa, Yugo, Matsui, Ko

“…Synaptic pruning is a fundamental process of neuronal circuit refinement in learning and memory. Accumulating evidence suggests that glia participates in…”
Get full text

Orexin directly excites orexin neurons through orexin 2 receptor by Yamanaka, Akihiro, Tabuchi, Sawako, Tsunematsu, Tomomi, Fukazawa, Yugo, Tominaga, Makoto

“…Orexin neurons (hypocretin neurons) have a critical role in the regulation of sleep/wakefulness, especially in the maintenance of arousal. Here, we revealed…”
Get full text

CAPS1 is involved in hippocampal synaptic plasticity and hippocampus-associated learning by Ishii, Chiaki, Shibano, Natsumi, Yamazaki, Mio, Arima, Tomoki, Kato, Yuna, Ishii, Yuki, Shinoda, Yo, Fukazawa, Yugo, Sadakata, Tetsushi, Sano, Yoshitake, Furuichi, Teiichi

“…Calcium-dependent activator protein for secretion 1 (CAPS1) is a key molecule in vesicular exocytosis, probably in the priming step. However, CAPS1’s role in…”
Get full text

Expression mapping, quantification, and complex formation of GluD1 and GluD2 glutamate receptors in adult mouse brain by Nakamoto, Chihiro, Konno, Kohtarou, Miyazaki, Taisuke, Nakatsukasa, Ena, Natsume, Rie, Abe, Manabu, Kawamura, Meiko, Fukazawa, Yugo, Shigemoto, Ryuichi, Yamasaki, Miwako, Sakimura, Kenji, Watanabe, Masahiko

“…In the cerebellum, GluD2 is exclusively expressed in Purkinje cells, where it regulates synapse formation and regeneration, synaptic plasticity, and motor…”
Get full text

Advantages of Acute Brain Slices Prepared at Physiological Temperature in the Characterization of Synaptic Functions by Eguchi, Kohgaku, Velicky, Philipp, Hollergschwandtner, Elena, Itakura, Makoto, Fukazawa, Yugo, Danzl, Johann Georg, Shigemoto, Ryuichi

“…Acute brain slice preparation is a powerful experimental model for investigating the characteristics of synaptic function in the brain. Although brain tissue…”
Get full text

Distribution of mRNA for GPR143, a receptor of 3,4-L-dihydroxyphenylalanine, and of immunoreactivities for nicotinic acetylcholine receptors in the nigrostriatal and mesolimbic regions by Kasahara, Yuka, Masukawa, Daiki, Nakamura, Yoshie, Murata, Koshi, Hashimoto, Tatsuo, Takizawa, Kohtaro, Koga, Motokazu, Nakamura, Fumio, Fukazawa, Yugo, Funakoshi, Kengo, Goshima, Yoshio

“…•We investigated the distribution of GPR143, a receptor of DOPA, and nAChR subunits.•GPR143 mRNA signals exist in the nigrostrial and mesolimbic dopaminergic…”
Get full text

Cellular Profiles of Prodynorphin and Preproenkephalin mRNA-Expressing Neurons in the Anterior Olfactory Tubercle of Mice by Maegawa, Ayako, Murata, Koshi, Kuroda, Kazuki, Fujieda, Shigeharu, Fukazawa, Yugo

“…The olfactory tubercle (OT) is a striatal region that receives olfactory inputs. mRNAs of prodynorphin (Pdyn) and preproenkephalin (Penk), precursors of…”
Get full text