Search Results - "Fukasawa, Masatomo"

A novel carbapenem antibiotic, SM-7338 structure-activity relationships by Sunagawa, M, Matsumura, H, Inoue, T, Fukasawa, M, Kato, M

“…A series of new carbapenem compounds, which have a pyrrolidin-3'-ylthio group substituted with various aminocarbonyl group at C-5' position as C-2 side chain,…”
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Comparison of two carbapenems, SM-7338 and imipenem: affinities for penicillin-binding proteins and morphological changes by Sumita, Y, Fukasawa, M, Okuda, T

“…We investigated the binding affinities of SM-7338 for penicillin-binding proteins (PBPs) and the morphological changes induced by it compared with those of…”
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Liposomal Amphotericin B by Fukasawa, Masatomo

“…Liposomal amphotericin B (AmBisome™) is a DDS (drug delivery system) formulation of amphotericin B (AMPH-B), and has been developed in an attempt to reduce the…”
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Structure-activity relationships of carbapenem and penem compounds for the convulsive property by Sunagawa, M, Matsumura, H, Fukasawa, M

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PC-766B, a new macrolide antibiotic produced by Nocardia brasiliensis. I. Taxonomy, fermentation and biological activity by Kumagai, K, Taya, K, Fukui, A, Fukasawa, M, Fukui, M, Nabeshima, S

“…An actinomycete strain SC-4710, a new soil isolate, was found to produce a new macrolide antibiotic, PC-766B. Chemotaxonomic analysis of the producing organism…”
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Synthesis and antibacterial activity of novel carbapenems with a catechol or hydroxypyridone moiety by Sunagawa, M, Sasaki, A, Yamaga, H, Shinagawa, H, Fukasawa, M, Sumita, Y

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A new series of carbapenem antibiotics with 5'-substituted pyrrolidinylthio group at C-2 position by Sunagawa, M, Matsumura, H, Inoue, T, Fukasawa, M, Kato, M

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New penem compounds with 5'-substituted pyrrolidinylthio group as a C-2 side chain; comparison of their biological properties with those of carbapenem compounds by Sunagawa, M, Matsumura, H, Inoue, T, Fukasawa, M

“…A series of new penem compounds with a C-2 side chain consisting of a pyrrolidin-3'-ylthio group substituted with various aminocarbonyl groups at the C-5'…”
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New orally active cephalosporin esters by Yamada, H, Ueda, S, Mutoh, M, Nagata, H, Nouda, H, Fukasawa, M, Okuda, T

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A novel character of acylaminobenzylpenicillin apalcillin, in binding to penicillin-binding proteins of Escherichia coli and Pseudomonas aeruginosa by Fukasawa, M, Noguchi, H, Mitsuhashi, S, Ishino, F, Matsuhashi, M, Komatsu, T

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IN VITRO AND IN VIVO POSTANTIBIOTIC EFFECT OF MEROPENEM by Tanio, Tomoharu, Fukasawa, Masatomo

“…In vitro and in vivo postantibiotic effects (PAE) of meropenem (MEPM) were compared with those of imipenem (IPM) or imipenem/cilastatin (IPM/CS) for in vivo…”
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Isolation of two types of Pseudomonas aeruginosa mutants highly sensitive to a specific group of beta-lactam antibiotics and with defect in penicillin-binding proteins by Noguchi, H, Fukasawa, M, Komatsu, T, Iyobe, S, Mitsuhashi, S

“…Two types of mutants highly sensitive to beta-lactam antibiotics were obtained from Pseudomonas aeruginosa PAO 2142 by treatment with…”
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MODE OF ACTION OF MEROPENEM, A NEW CARBAPENEM ANTIBIOTIC by Sumita, Yoshihiro, Tada, Eiko, Nouda, Hiroshi, Okuda, Takao, Fukasawa, Masatomo

“…We investigated the binding affinities of meropenem (MEPM) for penicillin-binding proteins (PBPs) and the morphological changes induced by it in Escherichia…”
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IN VITRO ANTIBACTERIAL ACTIVITY OF MEROPENEM by Fukasawa, Masatomo, Sumita, Yoshihiro, Tada, Eiko, Okuda, Takao

“…The in vitro antibacterial activity of meropenem (MEPM), a new carbapenem antibiotic, was compared with those of imipenem (IPM), cefazolin, cefotiam,…”
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EFFICACY OF MEROPENEM AGAINST EXPERIMENTAL RESPIRATORY TRACT INFECTION AND INTRA-RENAL INFECTION IN GUINEA PIGS by Tanio, Tomoharu, Sasaki, Tokiko, Okuda, Takao, Fukasawa, Masatomo

“…The in vivo efficacies of meropenem (MEPM), a new parenteral carbapenem, against experimental respiratory tract infection and intra-renal infection in guinea…”
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ASSAY OF MEROPENEM IN BODY FLUIDS AND TISSUES by Tomio, Teiji, Nouda, Hiroshi, Kohzuki, Tsuneo, Kato, Masuhiro, Okuda, Takao, Fukasawa, Masatomo

“…We performed a microbiological assay (bioasay) and HPLC methods for quantitative determination of meropenem (MEPM) in body fluid and tissue samples. When the…”
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GENERAL PHARMACOLOGICAL STUDIES ON MEROPENEM: EFFECTS ON RESPIRATION, CIRCULATORY SYSTEM AND OTHERS by Fukasawa, Masatomo, Sugimoto, Shin-ichi, Miyagishi, Akira, Edwards, J. R., Grindey, A. J.

“…The effects of meropenem (MEPM) on respiration, circulatory system and others were investigated as parts of a general pharmacological study of this antibiotic…”
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BACTERIOLOGICAL EVALUATIONS OF CEFPIRAMIDE (SM-1652): A NEW PARENTERALLY ACTIVE ANTI-PSEUDOMONAL CEPHALOSPORIN DERIVATIVE by KATO, MASUHIRO, FUKASAWA, MASATOMO, INOUE, MATSUHISA, MITSUHASHI, SUSUMU

“…In vitro and in vivo microbiological evaluations of cefpiramide (CPM, SM-1652) were compared with those of newly developed cephalosporins. The following…”
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IN VITRO AND IN VIVO MICROBIOLOGICAL EVALUATION OF CEFPIRAMIDE (SM-1652) by OKUDA, TAKAO, FUKASAWA, MASATOMO, NOGUCHI, HIROSHI, KOMATSU, TOSHIAKI, YANO, KUNIICHIRO

“…In vitro and in vivo microbiological evaluation of cefpiramide (CPM, SM-1652) has been carried out and, the following results were obtained. 1) Cefpiramide…”
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CEFPIRAMIDE (SM-1652), A NEW BROAD-SPECTRUM CEPHALOSPORIN: AFFINITY TO PENICILLINBINDING PROTEINS AND MORPHOLOGICAL ALTERATION by FUKASAWA, MASATOMO, KATO, MASUHIRO, OKUDA, TAKAO, KOMATSU, TOSHIAKI, YANO, KUNIICHIRO

“…Cefpiramide (CPM, SM-1652) is a new broad-spectrum cephalosporin with marked antipseudomonal activity. Effect of cefpiramide on penicillin binding proteins…”
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