Search Results - "Fukano, Reiji"

Alectinib for relapsed or refractory anaplastic lymphoma kinase‐positive anaplastic large cell lymphoma: An open‐label phase II trial by Fukano, Reiji, Mori, Tetsuya, Sekimizu, Masahiro, Choi, Ilseung, Kada, Akiko, Saito, Akiko Moriya, Asada, Ryuta, Takeuchi, Kengo, Terauchi, Takashi, Tateishi, Ukihide, Horibe, Keizo, Nagai, Hirokazu

“…Anaplastic lymphoma kinase (ALK) inhibition is expected to be a promising therapeutic strategy for ALK‐positive malignancies. We aimed to examine the efficacy…”
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Necrotic Change of Tunica Media Plays a Key Role in the Development of Coronary Artery Lesions in Kawasaki Disease by Okada, Seigo, Sakai, Aiko, Ohnishi, Yuji, Yasudo, Hiroki, Motonaga, Takahiro, Fukano, Reiji, Waniishi, Takako, Sugiyama, Masaya, Hasegawa, Shunji

“…Background: Alarmins resulting from cell death or oxidative stress are involved in the development of Kawasaki disease (KD) vasculitis. In a previous study, we…”
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Sarcopenia and obesity in long-term survivors of childhood leukemia/lymphoma: a report from a single institution by Nakayama, Hideki, Noguchi, Maiko, Fukano, Reiji, Ueda, Tamaki, Taguchi, Shizu, Yoshimaru, Kenichi, Namie, Michiko, Shimokawa, Mototsugu, Okamura, Jun

“…Background The incidence and background factors of sarcopenia and obesity in long-term survivors of childhood leukemia/lymphoma were not clear in Japan…”
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Prognostic value of minimal disseminated disease assessed using digital polymerase chain reaction for 3'ALK assays in pediatric anaplastic lymphoma kinasepositive anaplastic large cell lymphoma by Fukano, Reiji, Iijima-Yamashita, Yuka, Iwafuchi, Hideto, Nakazawa, Atsuko, Saito, Akiko M., Takimoto, Tetsuya, Sekimizu, Masahiro, Suehiro, Yutaka, Yamasaki, Takahiro, Hasegawa, Shunji, Mori, Tetsuya, Horibe, Keizo

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Modeling and targeting of erythroleukemia by hematopoietic genome editing by Iacobucci, Ilaria, Qu, Chunxu, Varotto, Elena, Janke, Laura J., Yang, Xu, Seth, Aman, Shelat, Anang, Friske, Jake D., Fukano, Reiji, Yu, Jiyang, Freeman, Burgess B., Kennedy, James A., Sperling, Adam S., Zheng, Rena, Wang, Yingzhe, Jogiraju, Harini, Dickerson, Kirsten M., Payne-Turner, Debbie, Morris, Sarah M., Hollis, Emily S., Ghosn, Nina, Haggard, Georgia E., Lindsley, R. Coleman, Ebert, Benjamin L., Mullighan, Charles G.

“…Acute erythroid leukemia (AEL) is characterized by a distinct morphology, mutational spectrum, lack of preclinical models, and poor prognosis. Here, using…”
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Histological characteristics of matrix metalloproteinase‐9 and tissue inhibitor of metalloproteinases‐1 in asthmatic murine model during A(H1N1)pdm09 infection by Kimura, Sasagu, Yasudo, Hiroki, Oga, Atsunori, Fukano, Reiji, Matsushige, Takeshi, Hamano, Hiroki, Hasegawa, Hideki, Nakajima, Noriko, Ainai, Akira, Itoh, Hiroshi, Shirabe, Komei, Toda, Shoichi, Atsuta, Ryo, Hasegawa, Shunji

“…Pandemic influenza virus A(H1N1)pdm09 infection occurred in healthy children and young adults, but asthmatic patients presented more rapid progression of…”
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The Effect of Vitamin K2 Supplementation on PIVKA-II Levels in Patients with Severe Motor and Intellectual Disabilities Undergoing Long-Term Tube Feeding by Ohmori, Hiromitsu, Kato, Akihiko, Shirai, Yuka, Fukano, Reiji, Nagae, Akiko, Yamasaki, Masami, Komenaka, Junko, Imamura, Eiji, Kumode, Masao, Miyachi, Takafumi

“…Nutritional support is essential for patients with severe motor and intellectual disabilities (SMID) to ensure the smooth provision of medical care. These…”
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Interleukin-33/ST2 Axis as Potential Biomarker and Therapeutic Target in Kawasaki Disease by Okada, Seigo, Yasudo, Hiroki, Ohnishi, Yuji, Matsuguma, Chie, Fukano, Reiji, Motonaga, Takahiro, Waniishi, Takako, Hasegawa, Shunji

“…— Kawasaki disease (KD) is an acute, self-limiting, febrile systemic vasculitis of unknown cause associated with the development of coronary artery lesions…”
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Low NUDT15 expression levels due to biallelic NUDT15 variants and 6‐mercaptopurine intolerance by Yoshida, Masanori, Brown, Scott A., Moriyama, Takaya, Nishii, Rina, Tsujimoto, Shin‐ichi, Yamada, Yuji, Yoshida, Kaoru, Shirai, Ryota, Osumi, Tomoo, Utano, Tomoyuki, Fukano, Reiji, Kudo, Ko, Sakaguchi, Kimiyoshi, Arakawa, Yuki, Koh, Katsuyoshi, Sekiguchi, Masahiro, Sekimizu, Masahiro, Miyamura, Takako, Ishida, Hisashi, Inukai, Takeshi, Tomizawa, Daisuke, Kiyokawa, Nobutaka, Kato, Motohiro, Yang, Jun J.

“…Summary 6‐Mercaptopurine (6‐MP) is widely used for the treatment of paediatric leukaemia and lymphoma. Recently, germline variants in the NUDT15 gene have been…”
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A single-center analysis of chronic graft-versus-host disease-free, relapse-free survival after alternative donor stem cell transplantation in children with hematological malignancies by Inagaki, Jiro, Fukano, Reiji, Noguchi, Maiko, Okamura, Jun

“…We assessed the clinical outcomes of allogeneic hematopoietic stem cell transplantation (SCT) from alternative donors for pediatric patients with hematological…”
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Rituximab-combined anthracycline-free chemotherapy in newly diagnosed paediatric and adolescent patients with non-high-risk aggressive mature B cell lymphoma: protocol for a single-arm, open-label, multicentre, phase II study (the Japan Children’s Cancer Group Multicentre Trial, JPLSG B-NHL-20) by Sekimizu, Masahiro, Fukano, Reiji, Koga, Yuhki, Mitsui, Tetsuo, Fujita, Naoto, Mori, Takeshi, Hori, Daiki, Tanaka, Makito, Ohki, Kentaro, Iwafuchi, Hideto, Nakazawa, Atsuko, Mori, Tetsuya, Kobayashi, Ryoji, Hashimoto, Hiroya, M. Saito, Akiko, Kamei, Michi

“…IntroductionChildren and adolescents with mature B cell non-Hodgkin lymphoma (B-NHL) are treated with short-intensive chemotherapy. The burden of short-term…”
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BRAF V600E -positive cells as molecular markers of bone marrow disease in pediatric Langerhans cell histiocytosis by Kudo, Ko, Toki, Tsutomu, Kanezaki, Rika, Tanaka, Tatsuhiko, Kamio, Takuya, Sato, Tomohiko, Sasaki, Shinya, Imamura, Masaru, Imai, Chihaya, Ando, Kumiko, Kakuda, Harumi, Doi, Takehiko, Kawaguchi, Hiroshi, Irie, Masahiro, Sasahara, Yoji, Tamura, Akihiro, Hasegawa, Daiichiro, Itakura, Yosuke, Watanabe, Kenichiro, Sakamoto, Kenichi, Shioda, Yoko, Kato, Motohiro, Kudo, Kazuko, Fukano, Reiji, Sato, Atsushi, Yagasaki, Hiroshi, Kanegane, Hirokazu, Kato, Itaru, Umeda, Katsutsugu, Adachi, Souichi, Kataoka, Tatsuki, Kurose, Akira, Nakazawa, Atsuko, Terui, Kiminori, Ito, Etsuro

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A Phase I/II Study of Crizotinib for Recurrent or Refractory Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma and a Phase I Study of Crizotinib for Recurrent or Refractory Neuroblastoma : Study Protocol for a Multicenter Single-arm Open-label Trial by Sekimizu, Masahiro, Osumi, Tomoo, Fukano, Reiji, Koga, Yuhki, Kada, Akiko, Saito, Akiko M, Mori, Tetsuya

“…Crizotinib is an inhibitor of multiple tyrosine kinases, including the anaplastic lymphoma kinase (ALK). Responses to crizotinib have also been reported in…”
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The effect of graft‐versus‐host disease on outcomes after allogeneic stem cell transplantation for refractory lymphoblastic lymphoma in children and young adults by Mitsui, Tetsuo, Fujita, Naoto, Koga, Yuhki, Fukano, Reiji, Osumi, Tomoo, Hama, Asahito, Koh, Katsuyoshi, Kakuda, Harumi, Inoue, Masami, Fukuda, Takahiro, Yabe, Hiromasa, Takita, Junko, Shimada, Akira, Hashii, Yoshiko, Sato, Atsushi, Atsuta, Yoshiko, Kanda, Yoshinobu, Suzumiya, Junji, Kobayashi, Ryoji

“…Background Patients with relapsed or refractory lymphoblastic lymphoma (LBL) have a poor prognosis. The efficacy of allogeneic blood stem cell transplantation…”
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Successful outcome with reduced-intensity condition regimen followed by allogeneic hematopoietic stem cell transplantation for relapsed or refractory anaplastic large-cell lymphoma by Fukano, Reiji, Mori, Tetsuya, Fujita, Naoto, Kobayashi, Ryoji, Mitsui, Tetsuo, Kato, Koji, Suzuki, Ritsuro, Suzumiya, Junji, Fukuda, Takahiro, Shindo, Motohiro, Maseki, Nobuo, Shimoyama, Tatsu, Okada, Keiko, Inoue, Masami, Inagaki, Jiro, Hashii, Yoshiko, Sato, Atsushi, Tabuchi, Ken

“…We report a retrospective analysis of 38 patients (age ≤ 30 years) who underwent allogeneic hematopoietic stem cell transplantation (allo-SCT) for relapsed or…”
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Haematopoietic stem cell transplantation for relapsed or refractory anaplastic large cell lymphoma: a study of children and adolescents in Japan by Fukano, Reiji, Mori, Tetsuya, Kobayashi, Ryoji, Mitsui, Tetsuo, Fujita, Naoto, Iwasaki, Fuminori, Suzumiya, Junji, Chin, Motoaki, Goto, Hiroaki, Takahashi, Yoshiyuki, Hara, Junichi, Park, Yong‐Dong, Inoue, Masami, Koga, Yuhki, Inagaki, Jiro, Sakamaki, Hisashi, Adachi, Souichi, Kawa, Keisei, Kato, Koji, Suzuki, Ritsuro

“…Summary To evaluate haematopoietic stem cell transplantation (HSCT) in children and adolescents, we reviewed the records of 47 patients who were ≤18 years, had…”
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Hematopoietic stem cell transplantation following unsuccessful salvage treatment for relapsed acute lymphoblastic leukemia in children by Inagaki, Jiro, Fukano, Reiji, Noguchi, Maiko, Kurauchi, Koichiro, Tanioka, Shinji, Okamura, Jun

“…Background For children who experience a re‐induction failure or multiple recurrences following the first relapse of acute lymphoblastic leukemia (ALL), it is…”
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A Multicenter, Open-label, Clinical Trial to Assess the Effectiveness and Safety of Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced-intensity Conditioning in Relapsed/refractory Anaplastic Large-cell Lymphoma in Children by Kada, Akiko, Fukano, Reiji, Mori, Tetsuya, Kamei, Michi, Tanaka, Fumiko, Ueyama, Junichi, Sekimizu, Masahiro, Osumi, Tomoo, Mori, Takeshi, Koga, Yuhki, Ohki, Kentaro, Fujita, Naoto, Mitsui, Tetsuo, Saito, Akiko M, Hashimoto, Hiroya, Kobayashi, Ryoji

“…No standard treatment for relapsed or refractory anaplastic large-cell lymphoma (ALCL) has been established. This study is a multicenter, open-label trial to…”
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Effective VCR/DEX pulse maintenance therapy in the KYCCSG ALL-02 protocol for pediatric acute lymphoblastic leukemia by Okamoto, Yasuhiro, Koga, Yuki, Inagaki, Jiro, Ozono, Shuichi, Ueda, Koichiro, Shimoura, Maiko, Itonaga, Nobuyoshi, Shinkoda, Yuichi, Moritake, Hiroshi, Nomura, Yuko, Nakayama, Hideki, Hotta, Noriko, Hidaka, Yasufumi, Shimonodan, Hidemi, Suga, Naohiro, Tanabe, Takayuki, Nakashima, Kentaro, Fukano, Reiji, Kawano, Yoshifumi

“…In a previous study of childhood acute lymphoblastic leukemia (ALL) by the Kyushu–Yamaguchi Children’s Cancer Study Group, ALL-96, we achieved a 72.1 % 5-year…”
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Phase II trial of CH5424802 (alectinib hydrochloride) for recurrent or refractory ALK-positive anaplastic large cell lymphoma: study protocol for a non-randomized non-controlled trial by Nagai, Hirokazu, Fukano, Reiji, Sekimizu, Masahiro, Kada, Akiko, M Saito, Akiko, Asada, Ryuta, Mori, Tetsuya

“…Currently, a standard therapy has not been established for recurrent or refractory anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. While…”
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