Search Results - "Fukada, Sandra Y"

Strontium Calcium Phosphate Nanotubes as Bioinspired Building Blocks for Bone Regeneration by Tovani, Camila B, Oliveira, Tamires M, Soares, Mariana P. R, Nassif, Nadine, Fukada, Sandra Y, Ciancaglini, Pietro, Gloter, Alexandre, Ramos, Ana P

“…Calcium phosphate (CaP)-based ceramics are the most investigated materials for bone repairing and regeneration. However, the clinical performance of commercial…”
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Galectin-3 Deficiency Reduces the Severity of Experimental Autoimmune Encephalomyelitis by Jiang, Hui-Rong, Al Rasebi, Zakeya, Mensah-Brown, Eric, Shahin, Allen, Xu, Damo, Goodyear, Carl S, Fukada, Sandra Y, Liu, Fu-Tong, Liew, Foo Y, Lukic, Miodrag L

“…Galectin-3 (Gal-3) is a member of the beta-galactoside-binding lectin family and plays an important role in inflammation. However, the precise role of Gal-3 in…”
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Regulation of type 17 helper T-cell function by nitric oxide during inflammation by Niedbala, Wanda, Alves-Filho, Jose C, Fukada, Sandra Y, Vieira, Silvio Manfredo, Mitani, Akio, Sonego, Fabiane, Mirchandani, Ananda, Nascimento, Daniele C, Cunha, Fernando Q, Liew, Foo Y

“…Type 17 helper T (Th17) cells are implicated in the pathogenesis many of human autoimmune diseases. Development of Th17 can be enhanced by the activation of…”
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Osteoprotective Effects of IL-33/ST2 Link to Osteoclast Apoptosis by Lima, Izabella L.A, Macari, Soraia, Madeira, Mila F.M, Rodrigues, Letícia F.D, Colavite, Priscila M, Garlet, Gustavo P, Soriani, Frederico M, Teixeira, Mauro M, Fukada, Sandra Y, Silva, Tarcília A

“…The relevance of IL-33 and its receptor ST2 for bone remodeling is not well-defined. Our aim was to assess the role and underlying mechanisms of IL-33/ST2 in…”
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IL-33 Mediates Antigen-Induced Cutaneous and Articular Hypernociception in Mice by Verri, Waldiceu A., Guerrero, Ana T. G., Fukada, Sandra Y., Valerio, Daniel A., Cunha, Thiago M., Xu, Damo, Ferreira, Sérgio H., Liew, Foo Y., Cunha, Fernando Q.

“…IL-33, a new member of the IL-1 family, signals through its receptor ST2 and induces T helper 2 (Th2) cytokine synthesis and mediates inflammatory response. We…”
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Interleukin-33 Receptor (ST2) Deficiency Improves the Outcome of Staphylococcus aureus -Induced Septic Arthritis by Staurengo-Ferrari, Larissa, Trevelin, Silvia C, Fattori, Victor, Nascimento, Daniele C, de Lima, Kalil A, Pelayo, Jacinta S, Figueiredo, Florêncio, Casagrande, Rubia, Fukada, Sandra Y, Teixeira, Mauro M, Cunha, Thiago M, Liew, Foo Y, Oliveira, Rene D, Louzada-Junior, Paulo, Cunha, Fernando Q, Alves-Filho, José C, Verri, Waldiceu A

“…The ST2 receptor is a member of the Toll/IL-1R superfamily and interleukin-33 (IL-33) is its agonist. Recently, it has been demonstrated that IL-33/ST2 axis…”
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Hydrogen Sulfide Augments Neutrophil Migration through Enhancement of Adhesion Molecule Expression and Prevention of CXCR2 Internalization: Role of ATP-Sensitive Potassium Channels by Dal-Secco, Daniela, Cunha, Thiago M, Freitas, Andressa, Alves-Filho, Jose Carlos, Souto, Fabricio O, Fukada, Sandra Y, Grespan, Renata, Alencar, Nylane M. N, Neto, Alberto F, Rossi, Marcos A, Ferreira, Sergio H, Hothersall, John S, Cunha, Fernando Q

“…In this study, we have addressed the role of H(2)S in modulating neutrophil migration in either innate (LPS-challenged naive mice) or adaptive (methylated BSA…”
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Hepatic Osteodystrophy: The Mechanism of Bone Loss in Hepatocellular Disease and the Effects of Pamidronate Treatment by Spirlandeli, Adriano L., Dick-de-Paula, Ingrid, Zamarioli, Ariane, Jorgetti, Vanda, Ramalho, Leandra N.Z., Nogueira-Barbosa, Marcello H., Volpon, Jose B., Jordão, Alceu A., Cunha, Fernando Q., Fukada, Sandra Y., de Paula, Francisco J.A.

“…The present study was designed to evaluate the bone phenotypes and mechanisms involved in bone disorders associated with hepatic osteodystrophy. Hepatocellular…”
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IL‐33 attenuates EAE by suppressing IL‐17 and IFN‐γ production and inducing alternatively activated macrophages by Jiang, Hui‐Rong, Milovanović, Marija, Allan, Debbie, Niedbala, Wanda, Besnard, Anne‐Galle, Fukada, Sandra Y., Alves‐Filho, Jose C., Togbe, Dieudonnée, Goodyear, Carl S., Linington, Christopher, Xu, Damo, Lukic, Miodrag L., Liew, Foo Y.

“…Interleukin (IL)‐33, a member of the IL‐1 cytokine family, is an important modulator of the immune system associated with several immune‐mediated disorders…”
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Cigarette smoke induces miR-132 in Th17 cells that enhance osteoclastogenesis in inflammatory arthritis by Donate, Paula B., de Lima, Kalil Alves, Peres, Raphael S., Almeida, Fausto, Fukada, Sandra Y., Silva, Tarcilia A., Nascimento, Daniele C., Cecilio, Nerry T., Talbot, Jhimmy, Oliveira, Rene D., Passos, Geraldo A., Alves-Filho, José Carlos, Cunha, Thiago M., Louzada-Junior, Paulo, Liew, Foo Y., Cunha, Fernando Q.

“…Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by joint destruction and severe morbidity. Cigarette smoking (CS) can exacerbate the…”
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AMPKα1 negatively regulates osteoclastogenesis and mitigates pathological bone loss by Ribeiro, Mariana S.P., Venturini, Lucas G.R., Speck-Hernandez, Cesar A., Alabarse, Paulo V.G., Xavier, Thais, Taira, Thaise M., Duffles, Letícia F., Cunha, Fernando Q., Fukada, Sandra Y.

“…Osteoclasts are specialized cells responsible for bone resorption, a highly energy-demanding process. Focus on osteoclast metabolism could be a key for the…”
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A nontoxic strontium nanoparticle that holds the potential to act upon osteocompetent cells: An in vitro and in vivo characterization by Hayann, Larwsk, da Rocha, Vitor Freire, Cândido, Marina Ferreira, Vicente, Raphael Martini, Andrilli, Luiz H. S., Fukada, Sandra Y., Brassesco, María Sol, Ciancaglini, Pietro, Engel, Edgard Eduard, Ramos, Ana Paula

“…Estrogen deficiency, long‐term immobilization, and/or aging are commonly related to bone mass loss, thus increasing the risk of fractures. One option for bone…”
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The flavonoid quercetin inhibits titanium dioxide (TiO2)-induced chronic arthritis in mice by Borghi, Sergio M., Mizokami, Sandra S., Pinho-Ribeiro, Felipe A., Fattori, Victor, Crespigio, Jefferson, Clemente-Napimoga, Juliana T., Napimoga, Marcelo H., Pitol, Dimitrius L., Issa, João P.M., Fukada, Sandra Y., Casagrande, Rubia, Verri, Waldiceu A.

“…Titanium dioxide (TiO2) is a common component of orthopedic prosthesis. However, prosthesis wear releases TiO2, which induces inflammation and osteolysis in…”
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IL‐33 attenuates the development of experimental autoimmune uveitis by Barbour, Mark, Allan, Debbie, Xu, Heping, Pei, Cheng, Chen, Mei, Niedbala, Wanda, Fukada, Sandra Y., Besnard, Anne‐Galle, Alves‐Filho, Jose C., Tong, Xiaoguang, Forrester, John V., Liew, Foo Yew, Jiang, Hui‐Rong

“…Interleukin‐33 (IL‐33) is associated with several important immune‐mediated disorders. However, its role in uveitis, an important eye inflammatory disease, is…”
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Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice by Ramos‐Junior, Erivan S, Leite, Gisele A, Carmo‐Silva, Cecilia C, Taira, Thaise M, Neves, Karla B, Colón, David F, da Silva, Lea AB, Salvador, Sergio L, Tostes, Rita C, Cunha, Fernando Q, Fukada, Sandra Y

“…ABSTRACT Chemerin is an adipokine that regulates adipogenesis and metabolic functions of mature adipocytes mainly through the activation of chemokine‐like…”
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Nitric oxide enhances Th9 cell differentiation and airway inflammation by Niedbala, Wanda, Besnard, Anne-Gaelle, Nascimento, Daniele Carvalho, Donate, Paula Barbim, Sonego, Fabiane, Yip, Edwin, Guabiraba, Rodrigo, Chang, Hyun-Dong, Fukada, Sandra Y., Salmond, Robert J., Schmitt, Edgar, Bopp, Tobias, Ryffel, Bernhard, Liew, Foo Y.

“…Th9 cells protect hosts against helminthic infection but also mediate allergic disease. Here we show that nitric oxide (NO) promotes Th9 cell polarization of…”
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Analysis of the mechanisms underlying the vasorelaxant action of angiotensin II in the isolated rat carotid by Tirapelli, Carlos R., Fukada, Sandra Y., de Godoy, Márcio A.F., de Oliveira, Ana M.

“…It has been suggested that low concentrations of angiotensin II cause vasoconstriction whereas high concentrations evoke vasodilation. Thus, this work aimed to…”
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Nitric oxide-induced regulatory T cells inhibit Th17 but not Th1 cell differentiation and function by Niedbala, Wanda, Besnard, Anne-Gaelle, Jiang, Hui R, Alves-Filho, Jose C, Fukada, Sandra Y, Nascimento, Daniela, Mitani, Akio, Pushparaj, Peter, Alqahtani, Mohammed H, Liew, Foo Y

“…NO is a free radical with pleiotropic functions. We have shown earlier that NO induces a population of CD4(+)CD25(+)Foxp3(-) regulatory T cells (NO-Tregs) that…”
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ST2 regulates bone loss in a site‐dependent and estrogen‐dependent manner by Macari, Soraia, Madeira, Mila F. M., Lima, Izabella L. A., Pereira, Thaís S. F., Dias, George J., Cirelli, Joni A., de Molon, Rafael S., Fukada, Sandra Y., Szawka, Raphael E., Garlet, Gustavo P., Teixeira, Mauro M., Silva, Tarcília A.

“…Interleukin‐33 (IL‐33) and its receptor, ST2, are implicated in bone remodeling. The lack of estrogen after menopause results in an accelerated bone loss. Here…”
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Role of regulatory T cells in long-term immune dysfunction associated with severe sepsis by Nascimento, Daniele C, Alves-Filho, José C, Sônego, Fabiane, Fukada, Sandra Y, Pereira, Marcelo S, Benjamim, Claudia, Zamboni, Dario S, Silva, João S, Cunha, Fernando Q

“…OBJECTIVE:To investigate the role of regulatory T cells in the modulation of long-term immune dysfunction during experimental sepsis. It is well established…”
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