Search Results - "Fukada, S Y"
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Chemokines in Oral Inflammatory Diseases: Apical Periodontitis and Periodontal Disease
Published in Journal of dental research (01-04-2007)“…The inflammatory oral diseases are characterized by the persistent migration of polymorphonuclear leukocytes, monocytes, lymphocytes, plasma and mast cells,…”
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Book Review Journal Article -
2
HBP/O-GlcNAcylation Metabolic Axis Regulates Bone Resorption Outcome
Published in Journal of dental research (01-04-2023)“…Osteoclasts play a key role in the regulation of bone mass and are highly active metabolically. Here we show that a metabolic reprogramming toward the…”
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Journal Article -
3
IL-33 Exacerbates Periodontal Disease through Induction of RANKL
Published in Journal of dental research (01-07-2015)“…Cytokines mediate the balance between protective and destructive immunity in periodontitis. We sought to investigate the role of IL-33 in periodontitis. The…”
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Journal Article -
4
NLRP12 Attenuates Inflammatory Bone Loss in Experimental Apical Periodontitis
Published in Journal of dental research (01-04-2019)“…Apical periodontitis is an inflammatory disorder that results from the host immune response to microbial infection through the dental pulp, leading to alveolar…”
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5
NOD2 Contributes to Porphyromonas gingivalis–induced Bone Resorption
Published in Journal of dental research (01-11-2014)“…The NOD-like receptors are cytoplasmic proteins that sense microbial by-products released by invasive bacteria. Although NOD1 and NOD2 are functionally…”
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Journal Article -
6
iNOS -derived Nitric Oxide Modulates Infection-stimulated Bone Loss
Published in Journal of dental research (01-12-2008)“…Nitric oxide (NO) derived from inducible nitric oxide synthase (iNOS) plays an important role in host defense, as well as in inflammation-induced tissue…”
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Journal Article -
7
Effects of nitric oxide on neutrophil influx depends on the tissue: role of leukotriene B4 and adhesion molecules
Published in British journal of pharmacology (01-03-2009)“…Background and purpose: We investigated the effect of nitric oxide synthase (NOS) inhibition on polymorphonuclear cell (PMN) influx in zymosan or…”
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Journal Article -
8
Gender‐specific vascular effects elicited by chronic ethanol consumption in rats: a role for inducible nitric oxide synthase
Published in British journal of pharmacology (01-02-2008)“…Background and purpose: Epidemiological data suggest that the risk of ethanol‐associated cardiovascular disease is greater in men than in women. This study…”
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Journal Article -
9
Short-chain fatty acids and FFAR2 as suppressors of bone resorption
Published in Bone (New York, N.Y.) (01-08-2019)“…Short-chain fatty acids (SCFAs) exert a variety of immune and metabolic functions by binding to G-protein-coupled receptors, mainly free fatty acid receptor 2…”
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Journal Article -
10
IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy
Published in Annals of the rheumatic diseases (01-09-2010)“…Interleukin 33 (IL-33) is a new member of the IL-1 family of cytokines which signals via its receptor, ST2 (IL-33R), and has an important role in Th2 and mast…”
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Journal Article -
11
Fructose 1,6-bisphosphate inhibits osteoclastogenesis by attenuating RANKL-induced NF-κB/NFATc-1
Published in Inflammation research (01-05-2019)“…Background Although some glycolytic intermediates have been shown to modulate several cell type formation and activation, the functional role of fructose…”
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Journal Article -
12
Fibroblast growth factor receptor 2 expression in apical periodontitis in mice
Published in International endodontic journal (01-08-2020)“…Aim To investigate the presence, localization and the possible correlation of the fibroblast growth factor receptor‐2 (FGFR2) with inflammatory resorption of…”
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13
Effect of intercellular adhesion molecule 1 deficiency on the development of apical periodontitis
Published in International endodontic journal (01-03-2020)“…Aim To evaluate the specific role of ICAM‐1 in host responses against endodontic infection. Methods Apical periodontitis was experimentally induced in the…”
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14
Interface-driven Sr-morin complexation at Langmuir monolayers for bioactive coating design
Published in Colloids and surfaces, B, Biointerfaces (01-09-2019)“…[Display omitted] •Sr-morin complex spontaneously forms at Langmuir monolayers.•Sr-morin complex formation change the lipid organization at the air-liquid…”
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15
Absence of interleukin 22 affects the oral microbiota and the progression of induced periapical lesions in murine teeth
Published in International endodontic journal (01-01-2015)“…Aim To evaluate the absence of IL‐22 on the progression of periapical lesions in wild‐type (WT) and IL‐22 knockout (IL‐22 KO) mice. Methodology The evaluation…”
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16
Intracerebroventricular effects of angiotensin II on a step-through passive avoidance task in rats
Published in Neurobiology of learning and memory (2004)“…A wealth of evidence indicates that angiotensin II (Ang II) is involved in learning and memory. However, the precise role of this peptide in these cognitive…”
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17
Protective effects of the angiotensin type 1 receptor antagonist losartan in infection-induced and arthritis-associated alveolar bone loss
Published in Journal of periodontal research (01-12-2015)“…Background and Objective The angiotensin type 1 (AT1) receptor has been implicated in the pathogenesis of inflammatory bone disorders. This study aimed to…”
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Journal Article -
18
Factors involved in the T helper type 1 and type 2 cell commitment and osteoclast regulation in inflammatory apical diseases
Published in Oral microbiology and immunology (01-02-2009)“…Introduction: Periapical chronic lesion formation involves activation of the immune response and alveolar bone resorption around the tooth apex. However, the…”
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Journal Article -
19
Effects of nitric oxide on neutrophil influx depends on the tissue: role of leukotriene B 4 and adhesion molecules
Published in British journal of pharmacology (01-03-2009)“…Background and purpose: We investigated the effect of nitric oxide synthase (NOS) inhibition on polymorphonuclear cell (PMN) influx in zymosan or…”
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Journal Article -
20
Dual role of CCL3/CCR1 in oral squamous cell carcinoma : Implications in tumor metastasis and local host defense
Published in Oncology reports (01-11-2007)“…Chemokines are small chemotactic cytokines that can induce the migration of leukocytes, activate inflammatory/immune responses and have recently been…”
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