Search Results - "Fujiuchi, Nobuko"

BRCA1 Phosphorylation by Aurora-A in the Regulation of G2 to M Transition by Ouchi, Mutsuko, Fujiuchi, Nobuko, Sasai, Kaori, Katayama, Hiroshi, Minamishima, Yohji A, Ongusaha, Pat P, Deng, Chuxia, Sen, Subrata, Lee, Sam W, Ouchi, Toru

“…Aurora-A/BTAK/STK15 localizes to the centrosome in the G 2 -M phase, and its kinase activity regulates the G 2 to M transition of the cell cycle. Previous…”
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Neoadjuvant chemotherapy with trastuzumab, docetaxel, and carboplatin administered every 3 weeks for Japanese women with HER2-positive primary breast cancer: efficacy and safety by Sugitani, Ikuko, Ueda, Shigeto, Sakurai, Takashi, Shigekawa, Takashi, Hirokawa, Eiko, Shimada, Hiroko, Takeuchi, Hideki, Matsuura, Kazuo, Misumi, Misono, Fujiuchi, Nobuko, Takahashi, Takao, Hasebe, Takahiro, Osaki, Akihiko, Saeki, Toshiaki

“…Background This phase II neoadjuvant study evaluated the efficacy and safety of a triweekly regimen of docetaxel and carboplatin in combination with…”
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Axillary ultrasound examination is useful for selecting patients optimally suited for sentinel lymph node biopsy after primary systemic chemotherapy by Shigekawa, Takashi, M.D, Sugitani, Ikuko, M.D, Takeuchi, Hideki, M.D., Ph.D, Misumi, Misono, M.D, Nakamiya, Noriko, M.D, Sugiyama, Michiko, M.D, Sano, Hiroshi, M.D, Matsuura, Kazuo, M.D., Ph.D, Takahashi, Takao, M.D., Ph.D, Fujiuchi, Nobuko, M.D., Ph.D, Osaki, Akihiko, M.D., Ph.D, Saeki, Toshiaki, M.D., Ph.D

“…Abstract Background Controversy surrounds the reliability of sentinel lymph node biopsy after primary systemic chemotherapy. In this study, we assessed…”
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A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway by AGLIPAY, Jason A, LEE, Sam W, OUCHI, Toru, OKADA, Shinya, FUJIUCHI, Nobuko, OHTSUKA, Takao, KWAK, Jennifer C, YI WANG, JOHNSTONE, Ricky W, CHUXIA DENG, JUN QIN

“…We identified IFI16 as a BRCA1-associated protein involved in p53-mediated apoptosis. IFI16 contains the Pyrin/PAAD/DAPIN domain, commonly found in cell…”
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Choice of Adjuvant Chemotherapy Based on Breast Cancer Subtype by Shimada, Hiroko, Fujiuchi, Nobuko, Saeki, Toshiaki

“…Adjuvant chemotherapy targets micrometastases. If micrometastases are destroyed, patients with breast cancer will be cured. Currently, in Japan, standard…”
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Requirement of IFI16 for the Maximal Activation of p53 Induced by Ionizing Radiation by Fujiuchi, Nobuko, Aglipay, Jason A, Ohtsuka, Takao, Maehara, Naoki, Sahin, Fikret, Su, Gloria H, Lee, Sam W, Ouchi, Toru

“…IFI16 is a member of the PYRIN superfamily that has been implicated in BRCA1-mediated apoptosis and inflammation signaling pathways. Here we report that most…”
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Successful treatment of leptomeningeal metastases from breast cancer using the combination of trastuzumab and capecitabine: a case report by Shigekawa, Takashi, Takeuchi, Hideki, Misumi, Misono, Matsuura, Kazuo, Sano, Hiroshi, Fujiuchi, Nobuko, Okubo, Katsuhiko, Osaki, Akihiko, Aogi, Kenjiro, Saeki, Toshiaki

“…We report a case of metastatic breast cancer with leptomeninges and multiple bone metastases that showed an excellent response to the combination of…”
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BiClamp forceps significantly shorten the operation time for breast surgery by Takeuchi, Hideki, Saeki, Toshiaki, Shigekawa, Takashi, Sano, Hiroshi, Nakamiya, Noriko, Matsuura, Kazuo, Misumi, Misono, Takahashi, Takao, Fujiuchi, Nobuko, Okubo, Katsuhiko, Osaki, Akihiko, Sakurai, Takaki, Koyama, Isamu

“…Purpose A novel approach was introduced for breast surgery using the BiClamp, a new bipolar thermal energy device, to avoid complications and to shorten the…”
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18F-Fluorodeoxyglucose positron emission tomography optimizes neoadjuvant chemotherapy for primary breast cancer to achieve pathological complete response by Ueda, Shigeto, Saeki, Toshiaki, Shigekawa, Takashi, Omata, Jiro, Moriya, Tomoyuki, Yamamoto, Junji, Osaki, Akihiko, Fujiuchi, Nobuko, Misumi, Misono, Takeuchi, Hideki, Sakurai, Takaki, Tsuda, Hitoshi, Tamura, Katsumi, Ishida, Jiro, Abe, Yoshiyuki, Imabayashi, Etsuko, Kuji, Ichiei, Matsuda, Hiroshi

“…Background To assess the usefulness of positron emission tomography combined with computed tomography using 18 F-fluorodeoxyglucose (FDG PET/CT) for optimizing…”
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Successful treatment of trastuzumab-resistant HER2-positive breast cancer with extensive liver metastases using the combination of trastuzumab and capecitabine - a case report by Shigekawa, Takashi, Takeuchi, Hideki, Misumi, Misono, Nakamiya, Noriko, Sugiyama, Michiko, Sugitani, Ikuko, Fujiuchi, Nobuko, Osaki, Akihiko, Saeki, Toshiaki

“…We report a case of a trastuzumab-resistant human epidermal growth factor receptor-2(HER2)-positive breast cancer patient with extensive liver metastases and…”
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A false positive for metastatic lymph nodes in the axillary region of a breast cancer patient following mastectomy by Fujiuchi, Nobuko, Saeki, Toshiaki, Takeuchi, Hideki, Sano, Hiroshi, Takahashi, Takao, Matsuura, Kazuo, Shigekawa, Takashi, Misumi, Misono, Nakamiya, Noriko, Okubo, Katsuhiko, Osaki, Akihiko, Sakurai, Takaki, Matsuda, Hiroshi

“…Recent advanced imaging modalities such as positron emission tomography (PET) detect malignancies using 2-[18F]-fluoro-2-deoxy- d -glucose (18-FDG) with high…”
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The incidence and management of bone metastasis from breast cancer by Saeki, Toshiaki, Ookubo, Katsuhiko, Takeuchi, Hideki, Fujiuchi, Nobuko

“…Mammary cancer is one of the solid malignancies, which easily metastasizes to bone. The frequency of bone metastases of breast cancer has been reported to be…”
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Current status of adjuvant chemotherapy for breast cancer by Takeuchi, Hideki, Okubo, Katsuhiko, Fujiuchi, Nobuko, Saeki, Toshiaki

“…Breast cancer is one of the most common malignancies among Japanese women. Approximately 40,000 new patients are diagnosed annually. In the USA, however,the…”
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Recent perspectives second-line chemotherapy for breast cancer by Fujiuchi, Nobuko, Ohokubo, Katsuhiko, Saeki, Toshiaki, Sasaki, Yasutsuna

“…The recent development of chemotherapeutic agents for breast cancer will be reviewed. The paradigm shift from CMF to anthracycline containg regimens +/-…”
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BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition by Ouchi, Mutsuko, Fujiuchi, Nobuko, Sasai, Kaori, Katayama, Hiroshi, Minamishima, Yohji A., Ongusaha, Pat P., Deng, Chuxia, Sen, Subrata, Lee, Sam W., Ouchi, Toru

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sup 18^F-Fluorodeoxyglucose positron emission tomography optimizes neoadjuvant chemotherapy for primary breast cancer to achieve pathological complete response by Ueda, Shigeto, Saeki, Toshiaki, Shigekawa, Takashi, Omata, Jiro, Moriya, Tomoyuki, Yamamoto, Junji, Osaki, Akihiko, Fujiuchi, Nobuko, Misumi, Misono, Takeuchi, Hideki, Sakurai, Takaki, Tsuda, Hitoshi, Tamura, Katsumi, Ishida, Jiro, Abe, Yoshiyuki, Imabayashi, Etsuko, Kuji, Ichiei, Matsuda, Hiroshi

“…To assess the usefulness of positron emission tomography combined with computed tomography using ^sup 18^F-fluorodeoxyglucose (FDG PET/CT) for optimizing…”
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Loss of p53-regulatory protein IFI16 induces NBS1 leading to activation of p53-mediated checkpint by phosphorylation of p53 SER37 by Tawara, Hideyuki

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Loss of p53-regulatory protein IFI16 induces NBS1 leading to activation of p53-mediated checkpoint by phosphorylation of p53 SER37 by Tawara, Hideyuki, Fujiuchi, Nobuko, Sironi, Juan, Martin, Sarah, Aglipay, Jason, Ouchi, Mutsuko, Taga, Makoto, Chen, Phang-Lang, Ouchi, Toru

“…Our previous results that IFI16 is involved in p53 transcription activity under conditions of ionizing radiation (IR), and that the protein is frequently lost…”
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